Canada finished second in Group B after a 2-1 defeat to Switzerland in their final group game, though their campaign had already been defined by a historic 6-0 thrashing of Qatar that included a Jonathan David hat-trick.
South Africa, priced at 12/5 to qualify, arrive having scraped through Group A on the back of a solitary open-play goal across three games, with a 1-0 win over South Korea enough to see them through as runners-up behind Mexico.
Canada are clear favourites to advance at 1/3 (1.33), with the draw at 13/5 (3.60) also carrying little appeal given the gulf in attacking quality between the two sides.
The player specials are where the real interest lies, and David stands out with some strong value options in those markets.
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Jonathan David to score anytime against South Africa
David endured a frustrating opener against Bosnia, registering three shots and seven touches in the opposition box in just 61 minutes before being withdrawn, yet the response against Qatar was emphatic.
The Juventus striker took eight shots, hit five on target, and posted an xG of 2.96 across 90 minutes. Across his two World Cup appearances, David leads the entire tournament for touches in the opposition box with 15, underlining just how central he is to everything Canada do in the final third.
South Africa scored only once from open play in the group stage and had less than 32 per cent of possession against South Korea, a setup that invites sustained pressure.
At 7/4 (2.75) with bet365, backing David to score anytime is the standout selection.
Other Jonathan David bets worth considering
David attempting four or more shots carries plenty of appeal at 6/5 (2.20), given he managed three attempts in just 61 minutes against a well-organised Bosnia side and eight against Qatar across a full 90.
Between the 2024 Copa America and the 2025 Gold Cup, David had either a goal or an assist in eight of nine games for Canada, highlighting his consistent involvement when the stakes are highest.
David converted 103 goals from an xG of just 63.5 during his time at Lille — finishing roughly 40 goals above expectation — and his two-footedness means defenders cannot simply shepherd him onto a weaker side.
With Alphonso Davies expected to start his first game of the tournament and stretch South Africa's backline from the left, David should find even more space to operate through the middle.
David to score or assist is also available at 21/20 (2.05) with bet365, rounding off the three selections, and is the most forgiving of the bunch for a forward who, when Canada scores, tends to have a hand in it.