Just four days after their dramatic Championship contest, Southampton and Leicester will battle in the FA Cup fourth round at St Mary's on Saturday.
The hosts came from three goals down to win 4-3 in a league contest in midweek, with both sides now battling to crack the FA Cup's final 32.
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Southampton vs Leicester City prediction: Repeat or revenge after Tuesday's comeback win?
Key stats
- Southampton have won their last three games and five of their last seven in all competitions.
- Leicester have lost their last four matches and are winless in their last six Championship games.
- Only basement side Sheffield Wednesday have conceded more Championship goals than Leicester City (51) this season.
Correct score prediction: Southampton 3-1 Leicester City
With momentum from Tuesday's comeback win away at Leicester, trailing 3-0 at the hour mark and winning 4-3, we back Southampton to again get the better of the Foxes with Tuesday's classic only worsening the visitors' struggles.
Pre-game odds and win probability: Saints to beat Foxes twice in a week?
- HOME: 4/5 (1.80) – 55.6%
- DRAW: 29/10 (3.90) – 25.6%
- AWAY: 3/1 (4.00) – 25.0%
*odds from Ladbrokes, subject to change
As shown by the implied probabilities, bookmakers give Southampton a clear edge in Saturday's cup tie with a 57.1% chance to win in regular time.
A 25.6% chance is given to a draw which would see the tie settled in extra time or a penalty shootout, while Leicester are given a 25% chance to avenge Tuesday's loss and win in 90 minutes. Also, feel free to check out our Today’s betting tips page, as well as our FA Cup predictions & betting tips page.
Most recent H2Hs: Historic comeback fresh in the memory
The two teams' prior H2H only came on Tuesday in the Championship – Leicester led 3-0 on the hour mark only for Southampton to snatch a 4-3 away win with the decisive goal coming in the 96th minute.
That completed a league double for Southampton, who won 3-0 in the home H2H against Leicester in November, while the Foxes' most memorable H2H win came in a 9-0 thrashing of the Saints in the Premier League in 2019.
England Championship 10/02/26
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England Championship 25/11/25
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England Premier League 03/05/25
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England Premier League 19/10/24
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England Championship 23/04/24
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Southampton preview: Changes after a successful week?
Southampton remain without Mads Roerslev, Jay Robinson and Oriol Romeu due to ongoing injuries.
Tonda Eckert may opt to rotate his squad after their three straight league wins, with Shea Charles, Ryan Manning, Cyle Larin and Ross Stewart hoping for starts after impacting Saturday's game off the bench.
Predicted lineup: Peretz (GK); Jelert, Wood, Harwood-Bellis, Manning; Charles, Downes; Matsuki, Scienza, Larin & Stewart
Last five results:
- 10/02/26: Leicester 3-4 Southampton (Championship)
- 07/02/26: Southampton 1-0 Watford (Championship)
- 31/01/26: Stoke 0-2 Southampton (Championship)
- 25/01/26: Portsmouth 1-1 Southampton (Championship)
- 21/01/26: Southampton 1-0 Sheffield United (Championship)
Leicester City preview: Injury issues persist
Leicester remain unable to call on Harry Souttar, Jannik Vestergaard, Hamza Choudhury, Jordan James, Joe Aribo, and Aaron Ramsey on Saturday as they remain confined to the treatment room.
Patson Daka, Abdul Fatawu and Divine Mukasa may all continue in attack after their goals on Tuesday as the Foxes hope to get back to form.
Predicted lineup: Begovic (GK); Pereira, Okoli, Lascelles, Kristiansen; Winks, Skipp; Fatawu, Mukasa, Mavididi & Daka
Last five results:
- 10/02/26: Leicester 3-4 Southampton (Championship)
- 07/02/26: Birmingham 2-1 Leicester (Championship)
- 31/01/26: Leicester 0-2 Charlton (Championship)
- 24/01/26: Leicester 1-2 Oxford (Championship)
- 20/01/26: Wrexham 1-1 Leicester (Championship)
Player to watch: Abdul Fatawu

Leicester's disappointing Championship campaign could have looked far worse heading into the run-in if it was not for winger Abdul Fatawu.
While the 21-year-old talent has also arguably not lived up to his quality for the entirety of the term, he moved onto eight Championship goals for the season with the third in last week's eventual defeat, having also contributed eight goals in 32 league appearances.
With Foxes strikers often failing to hit the net at a sufficient rate, they are increasingly reliant on Fatawu to produce match-winning moments from the right wing.