Olympique de Marseille will mark their return to the UEFA Champions League after a three-year absence with a mouthwatering clash against Real Madrid at Santiago Bernabeu on Tuesday, 16 September 2025.
View our free Real Madrid vs Marseille predictions below.
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Real Madrid vs Marseille predictions: Hosts to reign supreme
Key stats
- Marseille have suffered four defeats in as many encounters with Real Madrid.
- Real Madrid are currently on a five-match winning streak.
- Six of Real Madrid's last seven matches featured fewer than 11 corners.
Correct score prediction: Real Madrid 3-0 Marseille
Real Madrid have had a perfect start to their La Liga campaign, winning four out of four league matches. They are up against a Marseille side that lost their two away games without scoring a single goal.
Keeping in mind that Madrid have a perfect four wins from four against Marseille, we believe they will emerge victorious after 90 minutes.
Pre-game odds and win probability: Real Madrid are odds-on favourites
- HOME: 4/11 (1.36) – 73.3%
- DRAW: 9/2 (5.50) – 18.2%
- AWAY: 13/2 (7.50) – 13.3%
*Odds from Ladbrokes, subject to change
Ahead of this encounter, Real Madrid are the expected winners at 4/11 (1.36). Teams with these odds generally have a 73.3% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Real Madrid vs Marseille predictions, as well as our BetMGM signup offer for this month.
Also, keeping in mind that at least one team failed to score in three of Marseille's last four games, BTTS – No has an appealing look at 21/20 (2.05). That one has a 48.8% chance of landing.
Most recent H2Hs: Business as usual for Real Madrid?
These teams have met on four occasions, all in the UEFA Champions League. Interestingly, Real Madrid won all four meetings, averaging three goals per game.
Real Madrid preview: Eyeing their sixth consecutive victory
On the treatment table for Real Madrid, Eduardo Camavinga, Jude Bellingham, Ferland Mendy and Endrick are unavailable for selection, while Antonio Rudiger faces months on the sidelines due to a thigh injury.
Xabi Alonso could name an unchanged side from the one that started against Real Sociedad on Saturday, with Dani Ceballos and Aurelien Tchouameni as double pivots, while Kylian Mbappe plays as the lone striker.
Predicted lineup: Courtois (GK), Alexander-Arnold, Militao, Huijsen, Carreras, Tchouameni, Valverde, Guler, Diaz, Vini & Mbappe.
Last five matches
- Real Sociedad 1-2 Real Madrid
- Real Madrid 2-1 Mallorca
- Real Oviedo 0-3 Real Madrid
- Real Madrid 1-0 Osasuna
- Tirol 0-4 Real Madrid
Marseille preview: Hoping to improve their fortunes on the road
As for Marseille, Amine Gouiri sustained an injury against Lorient on Friday just before the half-time break and now becomes the only possible injury absentee for the visitors ahead of this key UEFA Champions League encounter.
Aside from Gouiri’s likely absence, it is expected that coach Roberto De Zerbi will make some changes from last time’s starting XI, with Pierre-Emerick Aubameyang a likely starter up front after being an unused substitute in the victory over Lorient.
Predicted lineup: De Lange (GK), Murillo, Pavard, Aguerd, Medina, Gomes, Kondogbia, Greenwood, Nadir, Weah & Aubameyang.
Last five matches
- Marseille 4-0 Lorient
- Lyon 1-0 Marseille
- Marseille 5-2 Paris
- Rennes 1-0 Marseille
- Marseille 3-1 Aston Villa
Player to watch: Kylian Mbappe
It was business as usual for Kylian Mbappe last weekend, as was directly involved in both of Madrid's goals in their 2-1 victory at Real Sociedad. The former Paris Saint-Germain forward will look to extend his scoring run across all competitions to four matches.