Real Madrid travel to the Benito Villamarin this weekend in the Spanish top flight. Our Real Betis vs Real Madrid prediction and La Liga betting tips consider whether the improving hosts can spring a surprise.
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Real Betis vs Real Madrid prediction: Antony to score in surprise home win
Key stats
- Our Real Betis vs Real Madrid betting tips take into account that 67% of Betis home games in La Liga have seen both teams score.
- They’ve avoided defeat in all four matches at home to top-six opponents so far.
- Real Madrid have only won two of their eight league games against top-eight opponents this season.
Correct score prediction: Real Betis 2-1 Real Madrid
Real Madrid have been struggling all season in the tougher league fixtures, whilst frequently dominating against the weaker teams.
With half an eye on next Tuesday’s Champions League Madrid derby, Carlo Ancelotti could rest a few regulars here. There’s every chance a much-improved Betis side, that has been strengthened by a couple of major January additions, could cause an upset.
Pre-game odds and win probability: Los Blancos the clear favourites
- HOME: 10/3 (4.33) – 23.1%
- DRAW: 29/10 (3.90) – 25.6%
- AWAY: 8/11 (1.73) – 57.9%
*odds from Ladbrokes, subject to change
The visitors are the favourites according to the Real Betis vs Real Madrid odds, with an implied probability of 57.9% that they win this match.
They head into the game following a 1-0 win at Real Sociedad in the Copa del Rey, with Endrick making a rare start and scoring the only goal.
As for Real Betis, their improvement continued with a 2-1 win at Getafe last time out, with Isco grabbing both goals.
For more from the upcoming matches in Europe, today’s free betting tips look at some of the best picks.
Most recent H2Hs: Four draws in the last six
Our Real Betis vs Real Madrid prediction suggests this could be another difficult game for Los Blancos who have struggled to kill off Betis in recent years.
The last two meetings in Seville have finished level, with the last Betis victory coming via a 2-1 margin in 2020.
Spain La Liga 01/03/25
Real Betis
Real Madrid
Spain La Liga 01/09/24
Real Madrid
Real Betis
Spain La Liga 25/05/24
Real Madrid
Real Betis
Spain La Liga 09/12/23
Real Betis
Real Madrid
Spain La Liga 05/03/23
Real Betis
Real Madrid
Real Betis preview: Antony available after red card rescinded
The hosts have Antony available after his red card at Getafe last weekend was rescinded. William Carvalho, Giovani Lo Celso, Marc Roca and Angel Ortiz are out injured.
Predicted Lineup: Adrian (GK), Perraud, Bartra, Llorente, Sabaly, Cardoso, Altimira, J. Rodriguez, Isco, Antony & C. Hernandez
Spain La Liga 11/05/25
D Osasuna 1 Real Betis 1 UEFA Conference League 08/05/25
D Fiorentina 2 Real Betis 2 Spain La Liga 04/05/25
W Espanyol 1 Real Betis 2 UEFA Conference League 01/05/25
W Fiorentina 1 Real Betis 2 Spain La Liga 24/04/25
W Valladolid 1 Real Betis 5
Real Madrid preview: Bellingham suspended again
The visitors are missing the suspended Jude Bellingham. Ancelotti is also missing Dani Carvajal and Eder Militao to injuries, while he may rotate in some areas ahead of the Champions League round-of-16.
Predicted Lineup: Courtois (GK), Mendy, Alaba, Asencio, Vazquez, Rodrygo, Modric, Valverde, B. Diaz, Vinicius & Mbappe
Spain La Liga 11/05/25
L Barcelona 4 Real Madrid 3 Spain La Liga 04/05/25
W Celta Vigo 2 Real Madrid 3 Spain Copa del Rey 26/04/25
L Barcelona 3 Real Madrid 2 Spain La Liga 23/04/25
W Getafe 0 Real Madrid 1 Spain La Liga 20/04/25
W Athletic Bilbao 0 Real Madrid 1
Player to watch – Antony
Since leaving Manchester, Antony has looked a much more confident and capable player. The 25-year-old has two goals and two assists from his four appearances so far in La Liga.

Antony’s big impact in Spain
The Brazilian’s overall numbers are also really impressive since moving to the Spanish top flight. He’s averaging 2.5 shots and 2.3 key passes per game so far.