Real Betis will welcome Osasuna to Estadio de la Cartuja for their La Liga encounter on Sunday, 28 September 2025.
View our free Real Betis vs Osasuna predictions below.
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Real Betis vs Osasuna predictions: A card fest
Key stats
- At least five cards were awarded in five of Real Betis' last six matches across all competitions.
- Four of Osasuna's last five games went above the 4.5-card line.
- Real Betis’ last five games produced goals at both ends.
Correct score prediction: Real Betis 2-1 Osasuna
Real Betis are unbeaten in their last four clashes with Osasuna (W3, D1). They scored exactly two goals in each victory, two of which ended 2-1.
Keeping in mind that Osasuna have lost three of three away games in La Liga this season, we are confident that Real Betis will emerge victorious after all is said and done.
Pre-game odds and win probability: Betis are clear favourites
- HOME: 3/4 (1.75) – 57.1%
- DRAW: 27/10 (3.70) – 27%
- AWAY: 7/2 (4.50) – 22.2%
*Odds from Ladbrokes, subject to change
Real Betis have struggled to find their best form this season, with only two wins in seven games across all competitions (D4, L1).
Manuel Pellegrini’s men have earned nine points from a possible 18 and are eighth in La Liga. They are up against 13th-placed Osasuna, who have a 2-1-3 win-draw-loss record.
Ahead of this encounter, Real Betis are the expected winners at 3/4 (1.75). Teams with these odds usually have a 57.1% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Real Betis vs Osasuna predictions.
We have also pointed out that Real Betis' last five matches featured goals at both ends. Keeping in mind that both teams found the net in five of the last six meetings between these teams, BTTS – Yes has an appealing look at 4/5 (1.80). That one has a 55.6% chance of landing.
Most recent H2Hs: Betis’ dominance to continue?
Osasuna suffered three defeats in the last four clashes between these teams and have not beaten Real Betis at this stadium in La Liga in 11 years (D1, L6).
Spain La Liga 11/05/25
Real Betis
Osasuna
Spain La Liga 19/10/24
Osasuna
Real Betis
Spain La Liga 05/05/24
Osasuna
Real Betis
Spain La Liga 29/10/23
Real Betis
Osasuna
Spain La Liga 22/04/23
Osasuna
Real Betis
Real Betis preview: Looking to extend their unbeaten run
With just one defeat after six La Liga games, Real Betis have managed things just fine in the absence of key playmaker Isco, who is yet to play any minutes this season for Los Verdiblancos.
Betis will still miss Isco’s services this weekend, alongside those of Nelson Deossa, Marc Bartra, and Diego Llorente, who are all ruled out with injuries, while former Arsenal man Hector Bellerin, who was doubtful for this game, could start at right-back.
Giovanni Lo Celso will be tasked to provide creativity from the middle once again, while Antony continues his trademark disturbance from the right side of the attacking third, as the hosts eye back-to-back wins in La Liga for the first time this season.
Predicted lineup: Lopez (GK), Bellerin, Natan, Gomez, Firpo, Fornals, Altimira, Lo Celso, Antony, Ezzalzouli & Hernandez.
Last five matches
- Real Betis 2-2 Nottingham Forest
- Real Betis 3-1 Real Sociedad
- Levante 2-2 Real Betis
- Real Betis 1-2 Athletic Bilbao
- Celta Vigo 1-1 Real Betis
Osasuna preview: Eyeing their first away win
Osasuna are in fine shape ahead of this trip to Seville, although Aimar Oroz remains ruled out due to a foot injury.
Head coach Alessio Lisci has deployed a three-man backline in every league game so far this season. While it has yielded two wins, a draw, and three losses, it can be said that this strategy leaves the team vulnerable at the back, having conceded five times in six outings.
The Italian gaffer does not seem to want to change his style at the moment, with Juan Cruz, Alejandro Catena and Flavien Boyomo set to start on Sunday night.
Predicted lineup: Herrera (GK), Cruz, Catena, Boyomo, Rosier, Torro, Moncayola, Bretones, Garcia, Budimir & Munoz.
Last five matches
- Osasuna 1-1 Elche
- Villarreal 2-1 Osasuna
- Osasuna 2-0 Rayo Vallecano
- Athletic Bilbao 0-1 Osasuna
- Espanyol 1-0 Osasuna
Player to watch: Antony
Antony put in a solid performance earlier this week, scoring once and providing an assist in Real Betis' 2-2 draw with Nottingham Forest in the UEFA Europa League. With no goal contributions in two La Liga assignments this season, it will be interesting to see how the former Manchester United player will perform on Sunday night.