All eyes will be on Estadio de la Cartuja as Real Betis host Atletico Madrid in the 10th round of La Liga on Monday, 27 October 2025.
View our free Real Betis vs Atletico Madrid predictions below.
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Real Betis vs Atletico Madrid predictions: Both teams to get on the scoresheet
Key stats
- Seven of Atletico Madrid's last nine matches produced goals at both ends.
- Real Betis are currently on an eight-match unbeaten run across all competitions.
- Atletico Madrid opened the scoring in seven of their last eight games.
Correct score prediction: Real Betis 1-1 Atletico Madrid
Real Betis are coming off back-to-back draws, while Atletico Madrid have drawn their last three away league games by the same 1-1 scoreline.
Pre-game odds and win probability: Real Betis are up against it
- HOME: 11/5 (3.20) – 31.2%
- DRAW: 27/10 (3.70) – 27%
- AWAY: 23/20 (2.15) – 46.5%
*Odds from Ladbrokes, subject to change
Atletico Madrid's seven-game unbeaten run across all competitions ended with a humiliating 4-0 defeat against Arsenal in the UEFA Champions League last week. Diego Simeone's men have struggled on the road and are still hunting for their first away win of the season.
On the other hand, Real Betis have been a tough team to beat, stringing together an eight-game unbeaten run (W4, D4). They have been one of La Liga's best home teams, having won three of four league matches at Estadio de la Cartuja this season.
Ahead of this encounter, Atletico Madrid and Real Betis have the same 4-4-1 win-draw-loss record and are fifth and sixth in La Liga, respectively.
Despite their struggles on the road, Atletico Madrid are the expected winners at 23/20 (2.15). Teams with these odds generally have a 46.5% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Real Betis vs Atletico Madrid predictions.
Also, bearing in mind that both teams found the net in seven of Atletico Madrid's last nine games, BTTS – Yes has an appealing look at 7/10 (1.70). That one has a 58.8% chance of landing.
Most recent H2Hs: Atletico’s dominance to continue?
Atletico Madrid cruised to a comfortable 4-1 victory the last time these teams clashed. They have a solid track record against Betis, having won nine of their last 12 skirmishes (D2, L1).
Spain La Liga 18/05/25
Atletico Madrid
Real Betis
Spain La Liga 27/10/24
Real Betis
Atletico Madrid
Spain La Liga 03/03/24
Atletico Madrid
Real Betis
Spain La Liga 20/08/23
Real Betis
Atletico Madrid
Spain La Liga 02/04/23
Atletico Madrid
Real Betis
Real Betis preview: Looking to extend their unbeaten run
Real Betis will look to return to scoring ways as their run of 37 games with at least one goal ended on Thursday in their Europa League encounter against Genk. Interestingly, the last two occasions the Andalusian side blanked were both against Belgian opponents, with Gent keeping them at bay during a Conference League playoff clash on 20 February.
Without playmaking maestro Isco Alarcon in the middle of the pack, coach Manuel Pellegrini has continued to tweak a couple of things in the starting XI to compensate for his long ankle injury absence, making Pablo Fornals rise to the occasion to create and dictate the tempo of the game deep from the middle.
Betis were not at their best last week, playing out a goalless draw with Genk as key players like Fornals, Cucho Hernandez, and Abdessamad Ezzalzouli featured off the bench. However, all three of them are expected to return to the starting XI for this La Liga fixture.
Predicted lineup: Lopez (GK), Firpo, Natan, Bartra, Bellerin, Amrabat, Fornals, Ezzalzouli, Lo Celso, Antony & Hernandez.
Last five matches
- Genk 0-0 Real Betis
- Villarreal 2-2 Real Betis
- Espanyol 1-2 Real Betis
- Ludogorets 0-2 Real Betis
- Real Betis 2-0 Osasuna
Atletico Madrid preview: Eyeing their first away win
Atletico Madrid have been terrible on the road this season, showcasing limited hunger to win, create, and attack efficiently in all six trips made across all competitions (D3, L3), with the recent embarrassing Champions League defeat to Arsenal at the Emirates putting them in bad shape ahead of this contest.
But while Diego Simeone and his troops are working to change their fortunes on the road, there is no shortage of options in the squad should the boss choose to shake things up here, as midfielders Johnny Cardoso and Matteo Ruggeri are his only fitness doubts heading into this Estadio de la Cartuja trip, a venue from which they left empty-handed last time.
Predicted lineup: Oblak (GK), Hancko, Gimenez, Le Normand, Llorente, Gonzalez, Koke, Barrios, Simeone, Griezmann & Alvarez.
Last five matches
- Arsenal 4-0 Atletico Madrid
- Atletico Madrid 1-0 Osasuna
- Atletico Madrid 1-1 Inter Milan (4-2 AP)
- Celta Vigo 1-1 Atletico Madrid
- Atletico Madrid 5-1 Eintracht Frankfurt
Player to watch: Julian Alvarez
Julian Alvarez has been impressive so far, scoring six goals and providing an assist in nine La Liga assignments this season.
However, the Argentine forward has drawn blanks in his last four doors for club and country. He will fancy his chances against Betis once again after scoring two goals and providing an assist in the last encounter between these sides.