All eyes will be on Estadio do Dragao as two of the top 5 teams in the Portuguese Primeira Liga go head-to-head on Sunday, 26 January. View our free Porto vs Santa Clara predictions below.
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Porto vs Santa Clara predictions: Hosts to lead at the break
Key stats
- Porto have a perfect nine wins from nine at home this season.
- Santa Clara trailed at the half-time break in five of their last six clashes with Porto.
- Nine of Santa Clara's last 11 games went below the 2.5-goal threshold.
- At least one team blanked in seven of Porto's last eight matches.
Correct score prediction: Porto 1-0 Santa Clara
To be fair, Porto have lost four consecutive matches in all competitions. However, they have been the best home team in the Portuguese top flight with a perfect nine wins from nine at Estadio do Dragao. Keeping in mind that Porto won 13 of their last 15 meetings with Santa Clara, we are confident that the hosts will get back to winning ways this weekend.
Pre-game odds and win probability: Porto are odds-on favourites
- HOME: 10/21 (1.48) – 67.7%
- DRAW: 16/5 (4.20) – 23.8%
- AWAY: 6/1 (7.00) – 14.3%
*Odds from Ladbrokes, subject to change
Things have not gone swimmingly for Santa Clara in recent weeks. They have suffered four defeats in their last six games, with a win a draw. Vasco Matos’ men have dropped to fifth in the Primeira Liga. They are two spots behind their hosts with 31 points from 18 league games.
At the time of publishing, Porto are the expected winners at 10/21 (1.48). Teams with these odds usually have a 67.7% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Porto vs Santa Clara predictions.
It is worth mentioning that at least one team failed to score in 13 of Santa Clara's last 17 matches, and in seven of Porto's last eight games. On that note, BTTS – No has an appealing look at 3/5 (1.60). That one has a 62.5% chance of landing.
Most recent H2Hs: Business as usual for Porto?
Porto were the victors in their last three meetings with Santa Clara. They also won 13 of the last 15 clashes between these sides (D1, L1).
Portugal Primeira Liga 16/08/24
Santa Clara
FC Porto
Portugal Cup 29/02/24
Santa Clara
FC Porto
Portugal Cup 07/02/24
Santa Clara
FC Porto
Portugal Primeira Liga 15/04/23
FC Porto
Santa Clara
Portugal Primeira Liga 29/10/22
Santa Clara
FC Porto
Porto preview: Looking to avoid a fifth consecutive defeat
Samu Aghehowa and Nico Gonzalez are both suspended for Porto this weekend.
On the injury front, Ivan Marcano, Marko Grujic, Martim Fernandez and Wendell will all be sidelined for the hosts.
Predicted lineup: Costa (GK), Moura, Otavio, Perez, Mario, Eustaquio, Mora, Galeno, Namaso, Vieira & Borges.
Portugal Primeira Liga 11/05/25
W
Boavista
1
FC Porto
2
Portugal Primeira Liga 02/05/25
W
Moreirense
1
FC Porto
3
Portugal Primeira Liga 26/04/25
L
Estrela
2
FC Porto
0
Portugal Primeira Liga 18/04/25
W
Famalicao
1
FC Porto
2
Portugal Primeira Liga 12/04/25
W
Casa Pia
0
FC Porto
1
Santa Clara preview: No new absentees
Defenders Diogo Calila and Pedro Pacheco are both ruled out of this game for Santa Clara.
Predicted lineup: Batista (GK), Lima, Rocha, Venancio, Soares, Ferreira, Firmino, Pereira, Lopes, Safira & Silva.
Portugal Primeira Liga 10/05/25
W
Famalicao
1
Santa Clara
2
Portugal Primeira Liga 03/05/25
D
Braga
1
Santa Clara
1
Portugal Primeira Liga 26/04/25
W
Arouca
0
Santa Clara
2
Portugal Primeira Liga 18/04/25
D
Rio Ave
1
Santa Clara
1
Portugal Primeira Liga 12/04/25
L
Sporting
1
Santa Clara
0
Player to watch: Wenderson Galeno

To be fair, Wenderson Galeno has not scored or registered an assist in his last 10 appearances for Porto. However, the Brazilian midfielder was on the scoresheet in the last two encounters between these teams. With the absence of the team's top scorer, it will be interesting to see if Galeno will get back to scoring ways.