* Betting odds were correct at the time of publication but are subject to change.
Man United vs Omonia Nicosia: Our top betting tips
Manchester United made hard work of the reverse fixture just last week albeit they did come away with the win. Will they make lighter work of their opponents when the Cypriots visit Old Trafford? Find out with our Man United vs Omonia Nicosia match preview with free tips, predictions and odds mentioned along the way.
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Man United to win -2
We kick off our tips for this game by backing Man United to win and we think they'll do so with ease this time hence we're using a -2 handicap. Last time these two met the match ended in a narrow 3-2 win for United but, in truth, it could have been a much wider margin of victory. Since then, United have won at Everton whilst Omonia Nicosia have lost to AEL Limassol. That Everton win for United will have injected some much needed confidence into the veins – especially into Cristiano Ronaldo – and that together with holding home advantage should see the Red Devils run rampant against an opponent who, let's face it, are seriously inferior.
Going over 3.5 goals
Our next prediction for this match looks at the total goals market and we are backing over 3.5. Last time these two met, which was last week, they shared a total of five goals and whilst the scorline might be different this time round we can see a few goals hitting the net. Two of Man United's last three games have gone over that 3.5 threshold now whilst two of Omonia Nicosia's last four have also gone north of the 3.5 cut off. When you look at the opportunities United created in the last match (they had 27 shots) goals are likely in this game – if they bag early then the floodgates could open too.
Here are the key stats & form guide for Man United vs Omonia Nicosia
Head to Head
06/10/22
UEFA Europa League UEL
Omonia Nicosia
Man Utd
2
3
Last Five - Man Utd
11/05/25
England Premier League EPL
West Ham
Man Utd
2
0
L
08/05/25
UEFA Europa League UEL
Athletic Bilbao
Man Utd
1
4
W
04/05/25
England Premier League EPL
Brentford
Man Utd
4
3
L
01/05/25
UEFA Europa League UEL
Athletic Bilbao
Man Utd
0
3
W
27/04/25
England Premier League EPL
Bournemouth
Man Utd
1
1
D
Last Five - Omonia Nicosia
07/05/25
Cyprus Cup Cyprus
AEK Larnaca
Omonia Nicosia
2
1
L
04/05/25
Cyprus Division 1 Cyprus
Apollon Limassol
Omonia Nicosia
0
1
W
30/04/25
Cyprus Cup Cyprus
AEK Larnaca
Omonia Nicosia
0
0
D
26/04/25
Cyprus Division 1 Cyprus
Pafos FC
Omonia Nicosia
0
3
W
22/04/25
Cyprus Division 1 Cyprus
AEK Larnaca
Omonia Nicosia
1
1
D
Can United put on a show for their home fans?
Man United might have made hard work of their trip to Cyprus last week but they ultimately got the win they needed to boost their qualification chances. They're now three points clear of Sheriff Tiraspol and look good value to make the next round albeit a win here and Sheriff losing to Sociedad would really firm up that prospect. For Omonia, they're winless without having been embarrassed in this group (yet). They are hugely unlikely to go through but a win – or draw – would be a huge result for their history books.
Man United came through the weekend largely unscathed in terms of injuries with Anthony Martial. How serious that injury is we don't yet know but, regardless, he won't be risked here. Harry Maguire and Donny van de Beek remain out.
Man United Predicted lineup – De Gea, Malacia, Martinez, Varane, Dalot, Eriksen, McTominay, Antony, Rashford, Fernandes, Ronaldo
Omonia Nicosia have a couple of injuries ahead of this match with Fouad Bachirou and Ioannis Kousoulos both out. That said, neither of those played United last week either and an unchanged lineup isn't unlikely.
Omonia Nicosia Predicted lineup – Fabiano, Matthews, Miletic, Yuste, Lang, Lecjaks, Diskerud, Barker, Bruno, Charalampous, Ansarifard
A quickfire FAQ on Man United vs Omonia Nicosia

- Where is the match being hosted? – Old Trafford
- Who do the bookmakers have as favourites? – Man United
- What time does the match kick off? 8 PM GMT