Manchester City vs Southampton – prediction, preview & betting tips – 25/04/2026
Can Pep Guardiola guide Man City to more glory? - Conor Molloy / Photo by IMAGO / Pro Sports Images

Manchester City's attention now turns towards the FA Cup after topping the Premier League table in midweek, as they face Southampton in the semi-final at Wembley Stadium on Saturday evening.

The Cityzens beat Burnley 1-0 at Turf Moor to move above Arsenal into first place in the table by virtue of goals scored, and so the mood will be high as they travel down to London.

Meanwhile, Southampton drew 2-2 at home to Bristol City and are still in the race to finish in at least the Championship play-off places, but Man City provide a much tougher test than they are used to.

Read our prediction, preview and betting tips for the game below, and make sure to check out our Today's betting tips page for more of our expert FA Cup predictions!

Manchester City vs. Southampton key stats

  • Man City are on a five-game winning streak in all competitions.
  • Southampton's recent draw ended their own eight-match winning run across all competitions.
  • Southampton have beaten Man City just once in the last 10 H2Hs (D3, L6).

Manchester City vs. Southampton preview: Cityzens to reach another final?

Man City vs. Southampton Tale of the Tape
Man City vs Southampton
1st (Premier League)Position4th (Championship)
70Points76
66Goals For77
29Goals Against53
14Clean Sheets11

Man City are now favourites for a domestic treble, after not long ago it was Arsenal that were talked about for a potential quadruple.

They beat the Gunners 2-0 in the Carabao Cup final, and have just replaced them in top spot of the Premier League.

The Cityzens are also the most feared team left in the FA Cup semi-finals, and will be huge favourites against Southampton to progress into yet another major final.

Pep Guardiola's side have won five in a row in all competitions, and as usual, are peaking at the business end of the season.

Southampton have also been in a rich vein of form themselves, as their recent draw against Bristol City ended an eight-match winning run across all competitions.

They produced the scalp of the FA cup quarter-finals, beating Arsenal 2-1 at St. Mary's Stadium.

However, at the neutral venue of Wembley, facing Man City is arguably an even bigger test.

Still, given their form, Southampton will feel they can give an almighty upset.

Manchester City vs. Southampton form guide & betting tips

Last 5 Form Guide (all competitions)
Man City vs Southampton
W-W-W-W-W Form W-W-W-W-D
12Goals For14
1Goals Against5
W-W-WFA Cup formW-W-W

Whispers predicts: Manchester City 3-1 Southampton

Man City are 3/13 favourites to win, but while we agree with the bookies, these odds are far too short for us.

Thus, our first pick is BTTS - Yes at 1/1, as Southampton are in great form and could cause the Cityzens problems.

We are also expecting an exciting and open game on the big Wembley pitch, and with both attacks in-form, Over 3.5 goals at 21/20 also catches the eye.

In terms of potential goalscorers, Antoine Semenyo netted against Liverpool in the quarter-final, and has scored three times in the FA Cup for Man City so far.

Semenyo to score anytime at 6/5 is therefore our final pick.

Overall, we are predicting a 3-1 Man City win, which is available at 10/1.

📈 Whispers' Tips

> BTTS - Yes at 1/1 | Likelihood: Probable

> Over 3.5 goals at 21/20 | Likelihood: Possible

> Semenyo to score anytime at 6/5 | Likelihood: Possible


Adam is a lead writer on Football Whispers. He is a big Arsenal fan, and also follows his local club Wealdstone, made famous by The Wealdstone Raider, who he has interviewed. Adam also follows darts, boxing, cricket and tennis, among many other sports.