Man Utd vs Southampton prediction, odds & betting tips – 16/01/2025
Casemiro is being urged to join Saudi Arabian club Al-Nassr by former teammate Cristiano Ronaldo - Photo by Imago
🔥 Our Hot tip

Over 2.5 total goals

Man Utd beat Southampton 3-0 in the pair's reverse league meeting back in September.

Manchester United will be buzzing following their penalty shootout victory over Arsenal in the FA Cup but now their focus returns to the Premier League and a game against bottom-of-the-table Southampton at Old Trafford on Thursday.

Man Utd vs Southampton prediction: Goals expected on Thursday

Key Stats

  • Over 2.5 goals have been produced in three of Man Utd's last six matches.
  • Four of Southampton's last six outings have featured at least three goals.
  • Bruno Fernandes joint-top scores in the league for Man Utd this season with four goals.

Correct score prediction: Man Utd 3-1 Southampton

We're backing Man Utd to claim a 3-1 victory on Thursday night against a Saints side that shipped five goals in their last league game against Brentford. The Red Devils haven't kept a single clean sheet in any of their last six matches so you can see why we've backed Southampton to get on the scoresheet at Old Trafford.

Pre-game odds and win probability: Man Utd the overwhelming favourite

  • HOME: 1/3 (1.33) – 75%
  • DRAW: 49/10 (5.90) – 16.9%
  • AWAY: 9/1 (10.00) – 10%

*odds from Ladbrokes, subject to change

Manchester United are the expected winner of this game at 75% and we can only see this game ending in victory for the home side.

You can find all our predictions for today's games on our football betting tips page.

Most recent H2Hs: The Red Devils lead

Manchester United have picked up two wins and three draws from their last five head-to-heads with Southampton but did claim all three points when the pair last met back in September courtesy of a 3-0 scoreline.

England Premier League 14/09/24

Southampton

Southampton

0
Man Utd

Man Utd

3

England Premier League 12/03/23

Man Utd

Man Utd

0
Southampton

Southampton

0

England Premier League 27/08/22

Southampton

Southampton

0
Man Utd

Man Utd

1

England Premier League 12/02/22

Man Utd

Man Utd

1
Southampton

Southampton

1

England Premier League 22/08/21

Southampton

Southampton

1
Man Utd

Man Utd

1

Man Utd preview: Improved in last two

Man Utd followed up their excellent 2-2 draw at Anfield by knocking Arsenal out of the FA Cup in their own backyard.

A goalless first was brought to life when Bruno Fernandes fired United in front in the 52nd minute but the sending off of Diogo Dalot just after the hour mark allowed Arsenal to equalise moments later. The game went to extra time and then penalties where a miss from Kai Havertz proved enough for the ten-men of United to progress into the Fourth Round draw.

Mason Mount, Victor Lindelof, Luke Shaw and Jonny Evans are all expected to miss out on Thursday due to injury.

Predicted lineup: Onana (GK), Maguire, Mazraoui, de Ligt, Dalot, Martínez, Fernandes, Ugarte, Mainoo, Diallo & Hojlund

England Premier League 11/05/25

L

West Ham

West Ham

2

Man Utd

Man Utd

0

UEFA Europa League 08/05/25

W

Athletic Bilbao

Athletic Bilbao

1

Man Utd

Man Utd

4

England Premier League 04/05/25

L

Brentford

Brentford

4

Man Utd

Man Utd

3

UEFA Europa League 01/05/25

W

Athletic Bilbao

Athletic Bilbao

0

Man Utd

Man Utd

3

England Premier League 27/04/25

D

Bournemouth

Bournemouth

1

Man Utd

Man Utd

1

Southampton preview: Lost four of last six

The Saints were well beaten in their last league game at home to Brentford, going down by five goals to nil in the end.

Southampton did at least progress in the FA Cup over the weekend, running out 3-0 winners at home against Championship side Swansea thanks to a goal from Kamal Sulemana and a brace from Tyler Dibling.

Jack Stephens, Ross Stewart and Flynn Downes make up the trio of Southampton players that could miss the trip to Old Trafford through injury.

Predicted lineup: Ramsdale (GK), Bednarek, Bree, Walker-Peters, Wood-Gordon, Harwood-Bellis, Aribo, Ugochukwu, Sulemana, Dibling & Onuachu

England Premier League 10/05/25

D

Man City

Man City

0

Southampton

Southampton

0

England Premier League 03/05/25

L

Leicester

Leicester

2

Southampton

Southampton

0

England Premier League 26/04/25

L

Fulham

Fulham

2

Southampton

Southampton

1

England Premier League 19/04/25

D

West Ham

West Ham

1

Southampton

Southampton

1

England Premier League 12/04/25

L

Aston Villa

Aston Villa

3

Southampton

Southampton

0

Player to watch: Bruno Fernandes

Manchester United captain Bruno Fernandes has played some of his best football of the season under the management of his fellow countryman Ruben Amorim.

bruno fernandes

Fernandes, who joint-top scores for Man Utd in the Premier League this season with four goals, has been one of the key playmakers for his club in the 2024/25 campaign, providing six assists.

Bruno to guide Man Utd to all three points?

We're expecting another big performance from Fernandes in a game that Manchester United should really be winning with relative ease as Southampton have only picked up six points so far this season.


James developed his own blog covering football transfers from across Europe's big leagues before becoming a regular match preview and betting tips writer and now has 10+ years experience covering club and international leagues and competitions across the globe.