Lyon vs Lille prediction
Lyon's 4-2 defeat at Strasbourg ended a four-game winning run - Photo by IMAGO
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Both teams have scored in three of the last four H2Hs.

In this article, we have given our Lyon vs Lille prediction, odds & betting tips ahead of their Ligue 1 clash on Saturday night.

At the time of writing, the hosts are in seventh place on 45 points from 27 games played, while the visitors are in fifth spot on 47 points from the same number of matches.

Lyon vs Lille prediction: Lyon to leapfrog Lille?

Key stats

  • Lyon's 4-2 defeat away to Strasbourg last time out ended a four-game winning streak.
  • Lille have only scored four goals in their previous five matches.
  • Lyon are unbeaten in four H2Hs.

Correct score prediction: Lyon 2-1 Lille

Lyon come into this match in better form, and with home advantage, we fancy them to beat Lille. The visitors have been largely toothless in front of goal of late, and so may not possess enough firepower to get a positive result.

Pre-game odds and win probability: Lyon favoured by bookmakers

  • HOME: 6/5 (2.20) – 45.5%
  • DRAW: 13/5 (3.60) – 27.8%
  • AWAY: 2/1 (3.00) – 33.3%

*Odds from Ladbrokes, subject to change

As shown by the implied probabilities, Lyon are favourites to take home all three points. A Lille victory away from home is the next fancied result, followed by a draw.

Do not forget to check out more of our best betting tips and predictions after you have dissected our Lyon vs Lille predictions.

Most recent H2Hs: Lyon unbeaten in four

Lyon are unbeaten in the previous four H2Hs, with Lille last winning in 2023. Three of the last four encounters have also seen both teams score, which come into play as they prepare to face off against each other once again.

France Ligue 1 01/11/24

Lille

Lille

1
Lyon

Lyon

1

France Ligue 1 06/05/24

Lille

Lille

3
Lyon

Lyon

4

France Ligue 1 03/05/24

Lille

Lille

0
Lyon

Lyon

0

France Cup 07/02/24

Lyon

Lyon

2
Lille

Lille

1

France Ligue 1 26/11/23

Lyon

Lyon

0
Lille

Lille

2

Lyon preview: Lacazette to lose out again?

Alexandre Lacazette could miss out again given the form of fellow striker Georges Mikautadze. Nicolas Tagliafico and Thiago Almada could start though after being left on the bench against Strasbourg following late international duty with Argentina.

Predicted lineup: Perri (GK), Maitland-Niles, Mata, Niakhate, Tagliafico, Tolisso, Veretout, Nuamah, Cherki, Almada & Mikautadze

France Ligue 1 10/05/25

L

Monaco

Monaco

2

Lyon

Lyon

0

France Ligue 1 04/05/25

L

Lens

Lens

2

Lyon

Lyon

1

France Ligue 1 26/04/25

W

Rennes

Rennes

1

Lyon

Lyon

4

France Ligue 1 20/04/25

L

St Etienne

St Etienne

2

Lyon

Lyon

1

UEFA Europa League 17/04/25

L

Man Utd

Man Utd

5

Lyon

Lyon

4

Lille preview: Alexsandro available again

Alexsandro is available again after serving a ban in their victory over Lens last time out, but fellow defenders Samuel Umtiti and Tiago Santos remain injured. Winger Edon Zhegrova also remains out with a groin problem.

Predicted lineup: Chevalier (GK), Meunier, Diakite, Alexsandro, Ismaily, Andre, Gomes, Mukau, Fernandez-Pardo, David & Haraldsson

France Ligue 1 10/05/25

L

Brest

Brest

2

Lille

Lille

0

France Ligue 1 04/05/25

D

Marseille

Marseille

1

Lille

Lille

1

France Ligue 1 27/04/25

W

Angers

Angers

0

Lille

Lille

2

France Ligue 1 20/04/25

W

Auxerre

Auxerre

1

Lille

Lille

3

France Ligue 1 12/04/25

W

Toulouse

Toulouse

1

Lille

Lille

2

Player to watch: Georges Mikautadze

Lyon's summer signing Georges Mikautadze
Georges Mikautadze is in great form for Lyon – Photo by Imago

Georges Mikautadze is keeping Alexandre Lacazette out of the team at the moment, and is easy to see why. His goal against Strasbourg was his eighth for club and country in just five games, while the Georgia international striker has also made a further five assists heading into Lyon's clash with Lille.


Adam is a lead writer on Football Whispers. He is a big Arsenal fan, and also follows his local club Wealdstone, made famous by The Wealdstone Raider, who he has interviewed. Adam also follows darts, boxing, cricket and tennis, among many other sports.