Separated by just four points inside the Ligue 1 top five, Lyon and Lille battle for bragging rights in what is expected to be an encounter bearing major ramifications at Stadium de Lyon on Sunday, 1 February.
Keep close tabs on French Ligue 1 predictions after viewing our key Lyon vs Lille tips below.
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Lyon vs Lille prediction: Hosts to extend the Mastiffs' woes
Key stats
- Lyon are on a nine-match winning streak across all competitions.
- Les Gones have averaged 1.68 goals per game this league season.
- Lille have conceded the highest goals amongst the top six (29).
- Les Dogues have lost five of their last six competitive matches (W1).
Correct score prediction: Lyon 3-1 Lille
Lyon clinched top spot in the UEFA Europa League phase after dispatching four goals past 10-man PAOK on the final matchday, extending their winning streak to nine consecutive games. Paulo Fonseca now turns his focus to Ligue 1, with a top three finish comfortably in sight.
In contrast, Lille’s Ligue 1 campaign shows no signs of relief, although they progressed into the UEL knockout play-off round as a result of their stoppage-time victory over SC Freiburg. The visitors lost five straight gams before the triumph, including three in the French top-flight.
With their home faithful backing them up, Lyon are undoubtedly the favourites to grab maximum points, with Lille expectedly falling out of the top-six contention after matchday 20.
Pre-game odds and win probability: Home advantage
- HOME: 10/11 (1.90) – 52.3%
- DRAW: 27/10 (3.70) – 27%
- AWAY: 14/5 (3.80) – 26.3%
*odds from Ladbrokes, subject to change
Lyon are aiming for a fifth straight Ligue 1 success for the first time in over five years. Their impressive home form is an indicator, backed by odds of 10/11 (1.90), suggesting a 52.3% chance of triumph.
Lille are looking to avoid a fourth consecutive Ligue 1 defeat for the first time since September 2016. Their pride is on the line in this matchup, but bookies view the visitors as underdogs with odds of 14/5 (3.80) – a 26.3% win probability rate.
Don’t forget to check out more of our football betting tips page after analysing our Lyon vs Lille predictions.
Most recent H2Hs: Can Lille turn things around?
Lyon have won five of their last six meetings against Lille, drawing the other one. This includes two of their recent victories in Coupe de France and Ligue 1, both by a single goal margin.
France Cup 11/01/26
Lille
Lyon
France Ligue 1 28/09/25
Lille
Lyon
France Ligue 1 05/04/25
Lyon
Lille
France Ligue 1 01/11/24
Lille
Lyon
France Ligue 1 06/05/24
Lille
Lyon
Lyon preview: Growing absentee list
Several players are sidelined for Lyon, including Malick Fofana, Ernest Nuamah, Orel Mangala, Corentin Tolisso and Nicolas Tagliafico.
Predicted lineup: Greif (GK), Maitland-Niles, Mata, Kluivert, Hateboer, Morton, Tessmann, Merah, Sulc, Moreira & Endrick
Last five matches:
- Lyon 4-2 PAOK (UEFA Europa League)
- Metz 2-5 Lyon (Ligue 1)
- Young Boys 0-1 Lyon (UEFA Europa League)
- Lyon 2-1 Brest (Ligue 1)
- Lille 1-2 Lyon (Coupe de France)
Lille preview: Can they turn the tide?
Hamza Igamane, Thomas Meunier, Osame Sahraoui and Nabil Bentaleb are amongst the ones sidelined for Lille.
Predicted lineup: Ozer (GK), Mandi, Ngoy, Alexsandro, Santos, Perraud, Mbembe, Bouaddi, Mbappe Lottin, Haraldsson & Giroud
Last five matches:
- Lille 1-0 Freiburg (UEFA Europa League)
- Lille 1-4 Strasbourg (Ligue 1)
- Celta Vigo 2-1 Lille (UFA Europa League)
- PSG 3-0 Lille (Ligue 1)
- Lille 1-2 Lyon (Coupe de France)
Player to watch: Endrick
Lyon fared well without the winter newcomer in the Europa League, and will only be boosted and delighted by his return to the starting eleven as Fonseca’s men continue their ascend in Ligue 1. He became the youngest foreign player ever to score a hattrick in Ligue 1 history, with his three goals gifting Lyon all three points in the 5-2 win over Metz.