Chasing their first Coupe de France title since 2011–12, five-time winners Lyon welcome Lens to the Parc Olympique Lyonnais for Wednesday night’s quarter-final clash.
Meanwhile, the Blood and Gold have lifted the trophy three times, with their most recent triumph coming in 1997–98.
Our Lyon vs Lens prediction provides a clear outlook on the contest alongside additional Coupe de France betting tips.
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Lyon vs Lens: Home advantage to prove decisive?
Key stats
- Each of Lens’ last five matches has featured at least eight corners, a trend also seen in five of Lyon’s most recent six outings.
- Four of Lens’ last five games have produced three or more goals.
- Lyon have won each of their last nine home matches across all competitions.
Correct score prediction: Lyon 2–1 Lens
After winning 13 matches in succession, Lyon have suffered back-to-back defeats, starting with a 3–1 loss at Strasbourg, followed by a dramatic 3–2 setback at Marseille.
Lens have also encountered a slight dip, losing 3–2 at home to Monaco before drawing 1–1 at Strasbourg, despite having won 14 of their previous 15 matches.
While both sides have seen their momentum stall, Lyon’s return to familiar surroundings – where they have been formidable – could prove crucial.
Paulo Fonseca’s men may edge what promises to be a highly competitive encounter, particularly after defeating Lens in their earlier league meeting this season.
Pre-match odds and win probability: Closely matched contest
- HOME: 6/5 (2.20) – 45.5%
- DRAW: 12/5 (3.40) – 29.4%
- AWAY: 7/5 (2.40) – 41.7%
*Odds from Ladbrokes, subject to change
This is a clash between two Ligue 1 heavyweights, with Lyon currently third in the table and Lens sitting second.
Given the competitive balance, it is no surprise the odds are tight. However, Lyon’s home advantage and strong recent cup pedigree — progressing beyond this stage in four of the last six campaigns — make them slight favourites at 45.5%.
Lens, meanwhile, have not reached the Coupe de France semi-finals in the past 15 seasons, which explains their lower 41.7% win probability.
Our hot tip — Lyon over 1.5 goals — offers value at 23/20 (2.15).
Most recent H2H: Lens with recent edge?
Lens hold a slight advantage in the last six meetings, winning three (D1, L2), including their last two visits to the Parc Olympique Lyonnais.
However, Lyon claimed a 1–0 away victory in the league meeting earlier this season, which could provide a psychological boost heading into this tie.
France Ligue 1 16/08/25
Lens
Lyon
France Ligue 1 04/05/25
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Lens
France Ligue 1 15/09/24
Lens
Lyon
France Ligue 1 03/03/24
Lyon
Lens
France Ligue 1 02/12/23
Lens
Lyon
Lyon preview: Defensive concern added to injury list
Defender Nicolas Tagliafico was forced off against Marseille and is now sidelined with a calf issue, adding to an already lengthy injury list.
Pavel Sulc and Afonso Moreira remain doubtful with hamstring problems, while Ruben Kluivert continues to recover from a muscle strain. Malick Fofana is also a doubt due to an ankle complaint.
Ernest Nuamah remains out with a cruciate ligament injury, though Orel Mangala could return after his lay-off.
Predicted XI: Descamps (GK), Abner, Mata, Niakhate, Hateboer, Nartey, Morton, Tessmann, Endrick, Yaremchuk & Karabec
Lyon’s last five results
- 01/03/26: Marseille 3–2 Lyon (Ligue 1)
- 22/02/26: Strasbourg 3–1 Lyon (Ligue 1)
- 15/02/26: Lyon 2–0 Nice (Ligue 1)
- 07/02/26: Nantes 0–1 Lyon (Ligue 1)
- 04/02/26: Lyon 2–0 Laval (Coupe de France)
Lens preview: Injury concerns linger
Lens emerged from their draw at Strasbourg without fresh issues, but Regis Gurtner and Samson Baidoo remain sidelined with hamstring problems, while Jonathan Gradit continues his recovery from a leg injury.
Ruben Aguilar is a doubt with a calf issue, and Kyllian Antonio is also uncertain due to a foot problem.
Predicted XI: Risser (GK), Ganiou, Celik, Udol, Abdulhamid, Bulatovic, Sangare, Sarr, Sotoca, Said & Edouard
Lens’ last five results
- 27/02/26: Strasbourg 1–1 Lens (Ligue 1)
- 21/02/26: Lens 2–3 Monaco (Ligue 1)
- 14/02/26: Paris FC 0–5 Lens (Ligue 1)
- 07/02/26: Lens 3–1 Rennes (Ligue 1)
- 04/02/26: Troyes 2–4 Lens (Coupe de France)
Player to watch: Endrick

Endrick has been influential since joining on loan from Real Madrid in January, registering five goals and four assists, including two in the defeat to Marseille.
The Brazilian scored in the previous round before Maxime Hautbois’ own goal sealed progression, and he could once again play a decisive role as Lyon pursue cup glory.