With their top-three hopes on the line, Lyon welcome mid-table Brest to Parc Olympique Lyonnais, a venue where the Pirates are winless this century, on Sunday, 18 January.
Keep close tabs on French Ligue 1 predictions after viewing our key Lyon vs Brest tips below.
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Lyon vs Brest prediction: Hosts to keep Pirates at bay
Key stats
- Lyon are on a five-match winning streak across all competitions.
- Les Gones have won four straight competitive matches at home.
- Brest have been awarded the most penalties this league season (7).
- The Pirates have lost five of their eight away league games this term (W2, D1).
Correct score prediction: Lyon 3-1 Brest
Lyon progressed to the Coupe de France last 16 by beating Lille 2-1, marking their fifth successive win across all competitions. Paulo Fonseca has successfully steered the Lyon ship in the right direction in recent weeks, with their 1-0 defeat to Lorient in early December their only loss in nine outings.
Meanwhile, Brest enter this round following a comfortable 2-0 victory over relegation contenders Auxerre – their only win in three recent outings. The Pirates occupy 11th position, and look set for another dismal finish to the season after their historic European appearance last campaign.
Lyon are clearly in superior form, and possess the individual quality to rob Brest of all three points in this midseason encounter.
Pre-game odds and win probability: OL all the way
- HOME: 8/13 (1.61) – 62.1%
- DRAW: 16/5 (4.20) – 23.8%
- AWAY: 19/5 (4.80) – 20.8%
*odds from Ladbrokes, subject to change
Racking up victories with regular strikes and an impressive backline, Lyon are the clear favourites in the eyes of bookmakers. The hosts are backed to win comfortably, with odds of 8/13 (1.61) suggesting a 62.1% chance of triumph.
Brest are in poor form away from home, losing four of their last six trips across all competitions (W1, D1). They are assigned odds of 19/5 (4.80), which indicates a 20.8% win probability rate.
Don’t forget to check out more of our football betting tips page after analysing our Lyon vs Brest predictions.
Most recent H2Hs: Who will claim bragging rights this time?
Across their last six meetings, Brest and Lyon have two wins apiece, while the rest two have been goalless stalemates. Brest have never recorded an away victory at Parc Olympique Lyonnais.
France Ligue 1 02/11/25
Brest
Lyon
France Ligue 1 02/03/25
Lyon
Brest
France Ligue 1 11/01/25
Brest
Lyon
France Ligue 1 14/04/24
Lyon
Brest
France Ligue 1 23/09/23
Brest
Lyon
Lyon preview: Three men missing
Corentin Tolisso is suspended for this clash due to a red card, while Moussa Niakhate will be playing at the AFCON final against Morocco. Malick Fofana remains the only injured absentee.
Predicted lineup: Greif (GK), Maitland-Niles, Mata, Kluivert, Tagliafico, Abner, Morton, Mangala, Merah, Sulc & Moreira
Last five matches:
- Lille 1-2 Lyon (Coupe de France)
- Monaco 1-3 Lyon (Ligue 1)
- Lyon 3-0 Saint-Cry Collonges (Coupe de France)
- Lyon 1-0 Le Havre (Ligue 1)
- Lyon 2-1 Go Ahead Eagles (UEFA Europa League)
Brest preview: Can they upset the odds?
Like Tolisso, Brest also have a suspension to deal with, as Julien Le Cardinal received a red card last match. Mama Balde and Kenny Lala are sidelined with injuries.
Predicted lineup: Coudert (GK), Zogbe, Chardonnet, Coulibaly, Guindo, Del Castillo, Chotard, Magnetti, Lascary, Mboup & Ajorque
Last five matches:
- Brest 2-0 Auxerre (Ligue 1)
- Avranches 1-1 Brest (5-4 on penalties) (Coupe de France)
- Rennes 3-1 Brest (Ligue 1)
- Brest 1-0 Monaco (Ligue 1)
- Strasbourg 1-2 Brest (Ligue 1)
Player to watch: Pavel Sulc

Lyon midfielder Sulc has been in stunning form in Ligue 1 and beyond, proving ever so significant across their recent run of victories. With match-winning braces across two of his last three appearances, the Czech talisman is expected to put in another 90 minutes worth applauding.