Liverpool will take on Southampton at Anfield on Saturday, 8 March in an ideal fixture for the Reds ahead of a crunch Champions League Round of 16 second leg with PSG next week.
With a 13-point lead established at the top of the Premier League table, Arne Slot is expected to shuffle the pack significantly this weekend which should mean opportunities for Liverpool's fringe players.
Southampton, meanwhile, are playing for nothing other than professional pride with the gap between themselves and safety now standing at 13 points.
As part of this weekend's round of Premier League betting tips, check out our Liverpool vs Southampton prediction below.
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Liverpool vs Southampton prediction: Elliott to star on Merseyside
Key stats
- Harvey Elliott scored in his last start against Southampton back in December.
- Elliott has scored three goals in his last 264 minutes of football (one goal every 88 minutes).
- Southampton haven't scored in three of their last four matches.
Correct score prediction: Liverpool 4-0 Southampton
Southampton are very familiar with this scoreline having lost their two most recent PL matches 4-0 and another one is on the cards this weekend. While Liverpool are expected to play a weakened team, it should still have far to much for Southampton who are already preparing for life back in the Championship.
Pre-game odds and win probability: Liverpool start as huge favourites
- HOME: 1/8 (1.13) – 88.9%
- DRAW: 9/1 (10.00) – 10%
- AWAY: 16/1 (17.00) – 5.9%
*Odds from Ladbrokes, subject to change
The Liverpool vs Southampton odds are a perfect illustration as to just how big the gap in quality is between both teams. Ladbrokes have priced Liverpool as the overwhelming favourites and have given them an 88.9% chance of victory. Meanwhile, Southampton have been given just a 5.9% chance of claiming all three points.
For more of the best picks, today’s free football betting tips look at the upcoming action in Europe and beyond.
Most recent H2Hs: Advantage Liverpool
Not only have Liverpool frequently raided Southampton for some of their best players over the years, they also regularly take them to the cleaners on the pitch. The Reds have won six of their last eight matches against the Saints and they have already beaten them twice this season. Southampton's last win over Liverpool came in January 2021.
England EFL Cup 18/12/24

Southampton

Liverpool
England Premier League 24/11/24

Southampton

Liverpool
England FA Cup 28/02/24

Liverpool

Southampton
England Premier League 28/05/23

Southampton

Liverpool
England Premier League 12/11/22

Liverpool

Southampton
Liverpool preview: Expect changes
PSG played Liverpool off the park on Wednesday night and it's a miracle that the Reds hold a 1-0 advantage ahead of the second leg. Liverpool aren't out of the woods yet and PSG will come to Anfield more determined than ever to topple Arne Slot's men so the star men are expected to be given the weekend off.
Predicted lineup: Alisson (GK), Alexander-Arnold, Quansah, Konate, Tsimikas, Jones, Endo, Elliott, Diaz, Chiesa, Nunez
England Premier League 13/04/25
W

West Ham
1

Liverpool
2
England Premier League 06/04/25
L

Fulham
3

Liverpool
2
England Premier League 02/04/25
W

Everton
0

Liverpool
1
England EFL Cup 16/03/25
L

Newcastle
2

Liverpool
1
UEFA Champions League 11/03/25
L

PSG
1

Liverpool
0
Southampton preview: Playing for pride
Southampton may well be as good as down with 11 games to go but they still have a duty to their fans to keep on trying week in, week out. If nothing else, the club will be desperate to avoid “beating” Derby County's record-low point tally of 11 points and one more win would save them the embarrassment of that.
Predicted lineup: Ramsdale (GK), Sugawara, Harwood-Bellis, Bednarek, Bella-Kotchap, Walker-Peters, Fernandes, Smallbone, Ugochukwu, Sulemana, Onuachu
England Premier League 12/04/25
L

Aston Villa
3

Southampton
0
England Premier League 06/04/25
L

Tottenham
3

Southampton
1
England Premier League 02/04/25
D

Crystal Palace
1

Southampton
1
England Premier League 15/03/25
L

Wolverhampton
2

Southampton
1
England Premier League 08/03/25
L

Liverpool
3

Southampton
1
Player to watch: Darwin Nunez

The enigma that is Darwin Nunez continues to offer Liverpool fans some hope that he may well turn out to be a good player for them one day. Off the bench in Paris, his determination and hold-up play from a long punt up the field played a huge role in the winner and he will likely get a chance from the off on Saturday. Can he capitalise with a goal or two?