On Saturday, Lecce will take on Sassuolo at the Stadio Via del Mare in the Serie A, with both teams looking to build on their previous win. Both sides resume their league campaign after the just-concluded 2026 FIFA World Cup qualifiers.
Heading into this game, the home team have struggled with their form in recent games but were able to claim a 1-0 victory against Parma in their last game.
Meanwhile, the Neroverdi have gone on to win back-to-back games in the league, with their last win before the international break being a narrow 1-0 victory against Hellas Verona.
Read our Lecce vs Sassuolo predictions and preview to find out, but remember to also check our other Serie A predictions.
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Lecce vs Sassuolo prediction: Visitors to claim narrow win
Key statistics
- Lecce have lost three times in their last five meetings with Sassuolo.
- There have been no BTTS in four of their last five meetings.
- I Neroverdi have won by a 1-0 margin in two of their last five encounters.
Correct score prediction: Lecce 0-1 Sassuolo
Sassuolo's recent wins have put them in a confident position to win this game, which is why we are predicting a 1-0 victory for the away team.
The Neroverdi have slightly more attacking power, having secured a 1-0 away win against Verona in their last outing. We believe Sassuolo can nick a narrow victory against Lecce in this game.
Pre-match odds and win probability: Sassuolo narrow favourites
- Home: 11/5 (3.20) – 31.3%
- Draw: 11/5 (3.20) – 31.3%
- Away: 29/20 (2.45) – 40.8%
*Odds provided by Ladbrokes. Subject to change.*
The Neroverdi enter the match as slim favourites with a 40.8% chance of victory at 2.45 odds. Lecce and a draw are both priced at 3.20, each reflecting a 31.3% implied probability. This points to a tight fixture where Sassuolo hold a slight edge heading into the encounter.
Most recent head-to-head: A history dominated by Sassuolo
Sassuolo have dominated this encounter in their last five meetings. The visitors have secured three victories against Lecce's one win, with one game ending in a draw. Four of the last six encounters finished with under 2.5 goals, suggesting a tight game. Notably, the most recent meeting between the two sides was a 2-0 victory for Sassuolo in September 2024.
Coppa Italia 24/09/24
Lecce
Sassuolo
Italy Serie A 21/04/24
Sassuolo
Lecce
Italy Serie A 06/10/23
Lecce
Sassuolo
Italy Serie A 25/02/23
Lecce
Sassuolo
Italy Serie A 20/08/22
Sassuolo
Lecce
After reviewing our key Lecce vs Sassuolo predictions, be sure to visit our website for the remaining football betting tips today.
Lecce preview: Key players out injured
The team will be without Balthazar Pierret, who is sidelined due to gastrointestinal discomfort. Filip Marchwinski and Gaby Jean are both ruled out with cruciate ligament injuries, with their returns expected later in October. Meanwhile, Matias Perez is also unavailable after suffering a thigh injury, and he is not expected to be back in action until November.
Predicted lineup: Falcone (GK), Veiga, Gaspar, Gabriel, Gallo, Coulibaly, Ramadani, Berisha, Pierotti, Stulic & Sottil
Last five fixtures
- 04.10.25 – Parma 0 – 1 Lecce
- 28.09.25 – Lecce 2 – 2 Bologna
- 23.09.25 – AC Milan 3 – 0 Lecce
- 19.09.25 – Lecce 1 – 2 Cagliari
- 14.09.25 – Atalanta 4 – 1 Lecce
Sassuolo preview: Two injuries in the squad
Heading into this game, Edoardo Pieragnolo is dealing with physical discomfort and is currently doubtful for the upcoming match, while Yeferson Paz is out with a calf injury. Their availability will depend on late fitness assessments ahead of kickoff.
Predicted lineup: Muric (GK), Walukiewicz, Idzes, Muharemovic, Doi, Vranckx, Matic, Kone, Berardi, Pinamonti & Lauriente
Last five fixtures
- 03.10.25 – Verona 0 – 1 Sassuolo
- 28.09.25 – Sassuolo 3 – 1 Udinese
- 24.09.25 – Como 3 – 0 Sassuolo
- 21.09.25 – Inter 2 – 1 Sassuolo
- 14.09.25 – Sassuolo 1 – 0 Lazio
Player to watch: Andrea Pinamonti
One player to watch out for is Sassuolo forward Andrea Pinamonti. The Italian attacker has been a bright spark in the attack, having scored two goals for his side this season. He is the team’s main goal threat and will play a key role if Sassuolo are to defeat Lecce in this game.