A place in the quarterfinal of the EFL Cup will be at stake when Grimsby Town host Brentford at Blundell Park on Tuesday, 28 October 2025.
View our free Grimsby vs Brentford predictions below.
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Grimsby vs Brentford predictions: Visitors to reign supreme
Key stats
- Grimsby suffered three defeats in their last four matches across all competitions.
- Brentford won three of their last four games.
- Six of Brentford's last eight matches produced goals at both ends.
Correct score prediction: Grimsby 1-3 Brentford
Brentford have been on an impressive run, defeating Liverpool, Manchester United and West Ham United in their last four games. While the Bees ply their trade in the English top flight, they are up against Grimsby, a League Two side.
To be fair, Grimsby have been impressive in the EFL Cup, as they knocked out Manchester United and Sheffield Wednesday in the previous two rounds of this competition.
However, the hosts’ recent run of results (W1, L3) does not inspire much confidence, and on that note, we are confident that Brentford will advance to the last eight.
Pre-game odds and win probability: Brentford are overwhelming favourites
- HOME: 7/1 (8.00) – 12.5%
- DRAW: 4/1 (5.00) – 20%
- AWAY: 1/3 (1.33) – 75%
*Odds from Ladbrokes, subject to change
Ahead of this EFL Cup Round of 16 clash, Brentford are the expected winners at 1/3 (1.33). Teams with these odds usually have a 75% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Grimsby vs Brentford predictions.
It is also worth mentioning that both teams were amongst the goals in six of Grimsby's last nine home games. Bearing in mind that six of Brentford's last eight matches produced goals at both ends, BTTS – Yes has an appealing look at 4/5 (1.80). That one has a 55.6% chance of landing.
Most recent H2Hs: First encounter in 16 years
While there have been 27 previous clashes between these sides since their first encounter in 1933, this will be their first meeting since March 2009.
Grimsby preview: Eyeing their first quarterfinal appearance in 40 years
Grimsby will set their sights on their first EFL Cup quarterfinal appearance since the 1984/85 season as they aim to give another Premier League side a run for their money following their shocking dismissal of Manchester United in Round 2.
Coach David Artell will not be able to call on the services of midfielder Zak Gilsenan and defender Douglas Tharme as both players are sidelined with injuries.
Predicted lineup: Pym (GK), Sweeney, McJannett, Warren, Rodgers, McEachran, Vernam, Walker, Green, Amaluzor & Kabia.
Last five matches
- Crewe 3-2 Grimsby
- Grimsby 1-0 Gillingham
- Grimsby 1-2 Colchester
- Grimsby 0-3 Doncaster
- Salford 0-2 Grimsby
Brentford preview: Eyeing three consecutive wins for the first time this season
Head coach Keith Andrews is expected to name a strong XI for this game, likely one that resembles the side that picked up maximum points off Liverpool last Saturday, except that holding midfielder Yehor Yarmolyuk picked up a new injury in that clash and will be unavailable.
Also sidelined with injuries for the visitors ahead of this matchup are Antoni Milambo, Aaron Hickey, and Joshua Dasilva.
Predicted lineup: Kelleher (GK), Kayode, Collins, Van den Berg, Ajer, Henderson Janelt, Ouattara, Damsgaard, Schade & Thiago.
Last five matches
- Brentford 3-2 Liverpool
- West Ham 0-2 Brentford
- Brentford 0-1 Man City
- Brentford 3-1 Man United
- Fulham 3-1 Brentford
Player to watch: Igor Thiago

Igor Thiago has been in sensational form, scoring four goals in his last four appearances for Brentford. The former Club Brugge forward found the net in his last two games and will look to extend his scoring run to three matches on Tuesday night.