Bayer Leverkusen vs PSG prediction, odds & betting tips – 21/10/2025
Bayer Leverkusen star Malik Tillman pictured in action - Photo by Imago
🔥 Our Hot tip

BTTS & Over 2.5

Bayer Leverkusen have found the net and conceded in eight of their last nine matches across all competitions, six of which produced more than 2.5 goals.

Current holders Paris Saint-Germain travel to Germany in search of their third straight win in this season’s Champions League as they face Bayer Leverkusen at the BayArena on Tuesday.

Luis Enrique’s side have begun their continental campaign in strong fashion, sweeping aside Atalanta on matchday one before coming from behind to secure a 2-1 triumph at Barcelona. Meanwhile, Die Werkself are still chasing their first win of the competition after opening with successive draws against Copenhagen and PSV Eindhoven.

The Parisians enter Tuesday’s encounter on the back of a pulsating 3-3 draw with Strasbourg in Ligue 1, extending their domestic run of stalemates after a 1-1 result against Lille. Leverkusen, on the other hand, will be buoyed by their 4-3 victory at Mainz over the weekend.

Read our Bayer Leverkusen vs PSG predictions and preview below, and remember to check our other Champions League betting tips for further insights.

Bayer Leverkusen vs PSG predictions: Expect fireworks at the BayArena

Key stats:

  • PSG have won both previous meetings with Leverkusen.
  • The French giants are on a five-match winning streak in the Champions League.
  • PSG have won at least one half in nine of their 11 competitive outings this season.
  • Leverkusen have lost three of their last six European outings (W1, D2).

Correct score prediction: Bayer Leverkusen 1-2 PSG

Both sides come into this contest on the back of thrilling performances, and while Leverkusen have displayed promising momentum in recent weeks, PSG’s pedigree in Europe could once again make the difference. The Parisians have won both previous meetings between the teams, each featuring at least three goals, and Tuesday’s clash promises to deliver another lively affair under the lights in Leverkusen.

Pre-match analysis: Visitors three times more likely to win

  • HOME: 18/5 (4.60) – 21.7%
  • DRAW: 16/5 (4.20) – 23.8%
  • AWAY: 13/20 (1.65) – 60.6%

*Odds courtesy of Ladbrokes; subject to change*

The bookmakers have placed PSG as strong favourites for this clash, giving them nearly triple the win probability of their hosts. The reigning champions have been handed a 60.6% chance of victory, while Leverkusen’s odds stand at 21.7%, with a draw priced at 23.8%.

Our hot tip of “both teams to score and over 2.5 goals” at 1.91 odds offers solid value considering the attacking nature of both sides. 

Most recent H2H: Visitors aim to extend their dominance

The last time these two sides met was in the 2014-15 Champions League round of 16, where PSG secured a 2-1 home win after cruising to a 4-0 victory in the first leg at the BayArena. 

Bayer Leverkusen preview: Kasper Hjulmand battles injury setbacks

Kasper Hjulmand continues to deal with a lengthy injury list as his side navigates a busy schedule. Exequiel Palacios remains sidelined with a groin issue, while Nathan Tella and Jarell Quansah are still recovering from knee problems. Axel Tape-Kobrissa, who was forced off in the game against PSV, has missed consecutive matches with a hamstring injury, making him doubtful for Tuesday’s tie.

Meanwhile, forward Patrik Schick is set to miss a fourth consecutive outing with a thigh strain, while Martin Terrier continues his rehabilitation from an Achilles tendon rupture. 

Predicted XI: Flekken, Andrich, Bade, Belocian, Arthur, Garcia, Fernandez, Grimaldo, Maza, Poku & Kofane

Leverkusen’s last five results:

  • 18/10/25: Mainz 3-4 Bayer Leverkusen (W)
  • 04/10/25: Bayer Leverkusen 2-0 Union Berlin (W)
  • 01/10/25: Bayer Leverkusen 1-1 PSV (D)
  • 27/09/25: St. Pauli 1-2 Bayer Leverkusen (W)
  • 21/09/25: Bayer Leverkusen 1-1 B. Monchengladbach (D)

PSG preview: Ousmane Dembele edges closer to return

PSG could once again be without captain Marquinhos as he continues to recover from a thigh problem, while Ousmane Dembele nears a long-awaited return from a hamstring strain. The French winger is expected to rejoin the squad later this week, as is Joao Neves, who has missed the last five games across all competitions. Fabian Ruiz also remains a doubt with a hip concern and may not feature in Germany.

Predicted XI: Chevalier, Hakimi, Zabarnyi, Pacho, Mendes, Kang-in, Vitinha, Doue, Kvaratskhelia, Ramos & Barcola

PSG’s last five results:

  • 17/10/25: PSG 3-3 Strasbourg (D)
  • 05/10/25: Lille 1-1 PSG (D)
  • 01/10/25: Barcelona 1-2 PSG (W)
  • 27/09/25: PSG 2-0 Auxerre (W)
  • 22/09/25: Marseille 1-0 PSG (L)

Player to watch: Christian Kofane

Christian Kofane (Photo credit – IMAGO/RHR-Foto)

Much of Leverkusen’s attacking responsibility will once again fall on the shoulders of 19-year-old Christian Kofane, who has impressed since stepping into the number nine role in the absence of Patrik Schick.

Kofane has now found the net in three consecutive matches, including the encounter against PSV on matchday two, and will be eager to continue his fine run in what could be the club’s toughest test of the season. 

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Adeyeye Oluwapelumi is a writer with over four years of experience covering football and a range of global sports. A passionate Arsenal fan since 2004, he brings sharp insight and a genuine love for the game to every piece.