Lille are hoping to claim another victory over opposition from the Spanish capital this week. Our Atletico Madrid vs Lille prediction and UEFA Champions League betting tips consider whether they can complete a famous Madrid double.
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Atletico Madrid vs Lille prediction: Griezmann to strike in home win
Key stats
- Our Atletico Madrid vs Lille betting tips take into account that Los Rojiblancos have won their last six Champions League home fixtures.
- Lille have lost three of their last five away games.
- The French side have only failed to score in one of their last five matches.
Correct score prediction: Atletico Madrid 2-1 Lille
Lille showed with their victory over Real Madrid on the previous matchday, that they can mix it with the European elite.
Their away form is considerably less impressive though and with Atleti boasting a 100% home record in this competition since the start of last term, Diego Simeone’s side should come out on top after 90 minutes.
Pre-game odds and win probability: Atleti the clear favourites
- HOME: 10/21 (1.48) – 67.7%
- DRAW: 16/5 (4.20) – 23.8%
- AWAY: 11/2 (6.50) – 15.4%
*odds from Ladbrokes, subject to change
The hosts are the favourites according to the Atletico Madrid vs Lille odds with an implied probability of 67.7% that they win this match.
Simeone’s side head into this match having come from behind to win 3-1 against Leganes on Sunday with Alexander Sorloth scoring twice.
As for Lille, they were involved in a goalless draw against Monaco on Friday night in Ligue 1.
For more of the best picks, today’s football betting tips look at the upcoming action in Europe and beyond.
Most recent H2Hs: Clubs set for first meeting
Our Atletico Madrid vs Lille prediction suggests it’ll be the Spanish side that wins the first ever competitive meeting.
Lille have avoided defeat in each of their last three Champions League games against Spanish sides though, taking four points off Sevilla in the 2021/22 group stage and beating Real Madrid 1-0 three weeks ago.
Atletico Madrid preview: Defensive and midfield issues
Defenders Robin Le Normand and Clement Lenglet are definitely out for the hosts. They also have concerns over Marcos Llorente, Pablo Barrios and Cesar Azpilicueta.
Predicted Lineup: Oblak (GK), Galan, Gimenez, Witsel, Lino, De Paul, Koke, Molina, Griezmann, Sorloth & Alvarez
Spain La Liga 10/05/25
W Real Sociedad 0 Atletico Madrid 4 Spain La Liga 03/05/25
D CD Alaves 0 Atletico Madrid 0 Spain La Liga 24/04/25
W Rayo Vallecano 0 Atletico Madrid 3 Spain La Liga 19/04/25
L Las Palmas 1 Atletico Madrid 0 Spain La Liga 14/04/25
W Valladolid 2 Atletico Madrid 4
Lille preview: Injuries mounting for Genesio
The visitors are expected to be without Samuel Umtiti, Ethan Mbappe, Nabil Bentaleb and Tiago Santos due to injury.
Predicted Lineup: Chevalier (GK), Gudmundsson, Ribeiro, Diakite, Meunier, Andre Gomes, Angel Gomes, Sahraoui, Cabella, Zhegrova & David
France Ligue 1 10/05/25
L Brest 2 Lille 0 France Ligue 1 04/05/25
D Marseille 1 Lille 1 France Ligue 1 27/04/25
W Angers 0 Lille 2 France Ligue 1 20/04/25
W Auxerre 1 Lille 3 France Ligue 1 12/04/25
W Toulouse 1 Lille 2
Player to watch – Antoine Griezmann
Antoine Griezmann is still the player who makes everything tick for Atleti in the final third. He has registered four goals and five assists in all competitions so far this term.
Griezmann impressing in Europe
The Frenchman was outstanding in Atleti’s first home Champions League game against RB Leipzig, scoring and assisting in that one. He averages 2.5 shots per game in the competition so far in the new league phase.