All eyes will be on Estadio de la Ceramica as Villarreal and Manchester City draw swords in the league phase of the UEFA Champions League on Tuesday, 21 October 2025.
View our free Villarreal vs Man City predictions below.
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Villarreal vs Man City predictions: Goals expected
Key stats
- At least three goals were scored in five of Villarreal's last six matches across all competitions.
- Manchester United are currently on an eight-match unbeaten run.
- Villarreal have no wins in their last three games.
Correct score prediction: Villarreal 1-3 Man City
Manchester City have enjoyed some fine form in recent weeks, as they are unbeaten in their last eight matches across all competitions (W6, D2), averaging over two goals in that stretch. They are up against a Villarreal side that failed to win their last three games.
It is worth mentioning that the Cityzens have won two of two previous skirmishes between these sides, and considering Villarreal's recent struggles, we are confident that the visitors will emerge victorious after 90 minutes.
Pre-game odds and win probability: Villarreal are up against it
- HOME: 10/3 (4.33) – 23.1%
- DRAW: 3/1 (4.00) – 25%
- AWAY: 8/11 (1.73) – 57.9%
*Odds from Ladbrokes, subject to change
While Villarreal are still hunting for their first win in the UEFA Champions League this season (D1, L1), Manchester City are unbeaten in two games so far (W1, D1).
Ahead of this clash, Man City are the expected winners at 8/11 (1.73). Teams with these odds generally have a 57.9% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Villarreal vs Man City predictions.
Also, keeping in mind that Villarreal drew first blood in four of their last five games, Villarreal to score first has an appealing look at 7/5 (2.40). That one has a 41.7% chance of landing.
Most recent H2Hs: First clash in almost 14 years
Villarreal and Manchester City have previously squared off against each other on two occasions, both in the group stage of the 2011/12 UEFA Champions League campaign. The Yellow Submarine lost both encounters.
UEFA Champions League 08/03/22
Man City
Villarreal
UEFA Champions League 15/02/22
Villarreal
Man City
Villarreal preview: Plagued by injuries
Things are continuing to look unconvincing on the injury front for Villarreal as up to four players are ruled out of this crucial UEFA Champions League contest, including Juan Foyth, Pau Cabanes (ACL), Willy Kambwala (hamstring) and Logan Costa (ACL).
Coach Marcelino kept out some of his key men from the clash against Real Betis over the weekend, as he looks to unleash them against the Cityzens in a starting XI likely resembling the side that was held by Juventus last time in this competition.
Predicted lineup: Tenas (GK), Mourino, Marin, Veiga, Pedraza, Parejo, Gueye, Comesana, Pepe, Buchanan & Mikautadze.
Last five matches
- Villarreal 2-2 Real Betis
- Real Madrid 3-1 Villarreal
- Villarreal 2-2 Juventus
- Villarreal 1-0 Athletic Bilbao
- Sevilla 1-2 Villarreal
Man City preview: Looking to extend their unbeaten run
As for Man City, there could be minutes for Rayan Cherki and Omar Marmoush on Wednesday as both players are back from injury layoffs and were in the squad that defeated Everton on Saturday. However, Rodri (hamstring), Abdukodir Khusanov (ankle), and Rayan Ait-Nouri are ruled out due to injury.
Star striker Erling Haaland is going through a brilliant scoring streak at the moment and is expected to be joined in the final third by Phil Foden and Jeremy Doku as Pep Guardiola’s men eye their second win of the league phase.
Predicted lineup: Donnarumma (GK), Nunes, Stones, Gvardiol, O'Reilly, Gonzalez, Silva, Reijnders, Foden, Doku & Haaland.
Last five matches
- Man City 2-0 Everton
- Brentford 0-1 Man City
- AS Monaco 2-2 Man City
- Man City 5-1 Burnley
- Huddersfield 0-2 Man City
Player to watch: Erling Haaland
Erling Haaland has put in back-to-back man-of-the-match performances, scoring a whopping five goals in his last two appearances for club and country. The former Borussia Dortmund forward has scored in 11 consecutive matches and will look to extend that streak on Tuesday night.