Cruzeiro will kick off their Copa Sudamericana campaign with a trip to Estadio 15 de Abril for their encounter with Union Santa Fe on Tuesday, 1 April 2025.
View our free Union Santa Fe vs Cruzeiro predictions below.
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Union Santa Fe vs Cruzeiro predictions: A low-scoring affair
Key stats
- Fewer than three goals were scored in five of Cruzeiro’s last seven matches.
- Eight of Union Santa Fe’s last 11 games went below the 2.5-goal threshold.
- Cruzeiro's last five games featured goals at both ends.
Correct score prediction: Union Santa Fe 1-1 Cruzeiro
Three of Cruzeiro's last four games ended in 1-1 draws after regulation time.
Pre-game odds and win probability: Cruzeiro are expected winners
- HOME: 15/8 (2.88) – 34.8%
- DRAW: 19/10 (2.90) – 34.5%
- AWAY: 11/8 (2.38) – 42.1%
*Odds from Ladbrokes, subject to change
Union Santa Fe have been going through a rough patch, as they are coming off back-to-back defeats and have lost three of their last four matches.
This is the Argentine team's third appearance in this competition. They were knocked out in the Round of 16 in their previous two outings (2020 & 2022).
On the other hand, Cruzeiro kicked off their Brasileiro Serie A campaign with a 2-1 victory over Mirassol last weekend. They advanced to the final of the CONMEBOL Sudamericana last season but lost to Racing Club.
Despite being on the road, Cruzeiro are the expected winners at 11/8 (2.38). Teams with these odds usually have a 42.1% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Union Santa Fe vs Cruzeiro predictions.
It is also worth mentioning that both teams were on the scoresheet in nine of Cruzeiro's last 10 games. On that note, BTTS – Yes has an appealing look at 5/4 (2.25). That one has a 44.4% chance of landing.
Most recent H2Hs: First clash in history
These sides will meet for the first time on Tuesday night.
It is worth mentioning that Union Santa Fe have a 1-3-2 win-draw-loss record in six previous encounters with Brazilian teams, while Cruzeiro have a 31-10-22 record in 63 clashes with Argentine opponents.
Union Santa Fe preview: Looking to turn their fortunes around
There are injury concerns for the hosts going into this contest, with up to three players expected to be ruled out, including centre-forward Jose Angulo (meniscus tear), left-back Bruno Pitton (knock), and centre-forward Marcelo Estigarribia (muscular problems).
Predicted lineup: Cardozo (GK), Blanco, Corvalan, Pardo, Paz, Vargas, M. Pitton, Profini, Fragapane, Colazo & Domina.
Copa Sudamericana 14/05/25
L
Mushuc Runa
1
Union Santa Fe
0
Copa Sudamericana 07/05/25
L
Palestino
2
Union Santa Fe
1
Argentina Liga Profesional 02/05/25
D
Belgrano
1
Union Santa Fe
1
Argentina Liga Profesional 28/04/25
L
Barracas Central
2
Union Santa Fe
1
Copa Sudamericana 24/04/25
L
Mushuc Runa
3
Union Santa Fe
0
Cruzeiro preview: No new absentees
Coach Leonardo Jardim will not be able to call upon the services of Juan Dinenno (ACL), and Joao Marcelo (knee) for this clash.
Predicted lineup: Cassio (GK), William, Bruno, Gamarra, Kaiki, Henrique, Wallace, Wanderson, Dudu, Jorge & Barbosa.
Brazil Serie A 11/05/25
W
Sport Recife
0
Cruzeiro
4
Copa Sudamericana 08/05/25
D
Mushuc Runa
1
Cruzeiro
1
Brazil Serie A 04/05/25
W
Flamengo
1
Cruzeiro
2
Copa do Brasil 02/05/25
W
Vila Nova
0
Cruzeiro
2
Brazil Serie A 27/04/25
W
Vasco da Gama
0
Cruzeiro
1
Player to watch: Gabriel Barbosa
Gabriel Barbosa has been in sensational form in recent months, scoring seven goals in his last eight appearances across all competitions. The former Inter Milan forward has scored in back-to-back games and will look to extend that run on Tuesday night.