FC Twente welcome Belgian side Union St Gilloise on Thursday night, with both sides hoping to record their first Europa League wins of the season. Continue reading for our Twente vs Union St Gilloise predictions and much more.

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Twente vs Union St Gilloise prediction: Three points are a must
- Both Twente and Union St Gilloise come into this game outside the Europa League's knockout playoff spots.
- Despite this, both sides are in decent form, and are unbeaten in their last five respective outings.
- Twente are yet to keep a clean sheet in European competition this season.
Correct score prediction: Twente 2-1 Union St Gilloise
This pair come into this game in similar form, and just a point apart in the league table, pointing to a closely fought encounter.
However, we're backing Twente to edge out the team from south of the border. They have played tougher opponents than their visitors, better players and have home advantage.
Pre-game odds and win probability: Too close to call
HOME: 6/5 (2.20) – 45.5%
DRAW: 21/10 (3.10) – 32.3%
AWAY: 5/2 (3.50) – 28.6%
*Odds from Ladbrokes, subject to change
By a slim margin, the bookmakers' expected winner in this game is Twente. Their odds of 6/5 imply a 45.5% likelihood of victory, a probability that's far from certain.
Feel free to take a look at our football betting tips page to check out our other predictions and tips!
Recent H2Hs: A first meeting
Despite both these clubs' rich histories, they have never met in a competitive fixture. Who will strike the opening blow?
Twente preview: A tough start
Twente have had quite the baptism of fire on their return to the Europa League for the first time in a decade. They have already played Lazio, Manchester United, Fenerbahce and Nice.
They have secured a creditable point in three of those four games, but they will know that they need to start picking up wins to leap up into the playoff spots.
The only major absentee for Twente is right-back Bart van Rooij, who saw red in the 2-2 draw with Nice.
Predicted lineup: Tyton (GK), Kuipers, Lagerbielke, Bruns, Salah-Eddine, Besselink, Steijn, Rots, Regeer, Ltaief, Lammers
Netherlands Eredivisie 11/05/25
W

FC Utrecht
0

FC Twente
2
Netherlands Eredivisie 04/05/25
W

Sparta Rotterdam
0

FC Twente
2
Netherlands Eredivisie 24/04/25
L

PSV
3

FC Twente
1
Netherlands Eredivisie 13/04/25
D

PEC Zwolle
1

FC Twente
1
Netherlands Eredivisie 05/04/25
D

Fortuna Sittard
1

FC Twente
1
Union St Gilloise preview: a must win
After a dark age, Union St Gilloise have become European regulars again, featuring in the Europa or Conference Leagues the last three seasons.
Things have been tougher going for the Brussels club this season, who are currently ninth domestically, and have taken just two points from four Europa League games.
Twente will be another tough assignment. But having beaten the likes of Liverpool and Eintracht Frankfurt in recent seasons, Sebastien Pocognoli's side will be more than up for the challenge.
Predicted lineup: Moris (GK), Sykes, Burgess, Machida, Mac Allister, Khalaili, Vanhoutte, Sadiki, Niang, Ivanovic, Akinpelu
Belgium First Division A 10/05/25
W

Anderlecht
0

Union Saint Gilloise
1
Belgium First Division A 03/05/25
W

Genk
0

Union Saint Gilloise
1
Belgium First Division A 27/04/25
D

Club Brugge
0

Union Saint Gilloise
0
Belgium First Division A 24/04/25
W

Club Brugge
0

Union Saint Gilloise
1
Belgium First Division A 20/04/25
W

Genk
1

Union Saint Gilloise
2

Player to watch: Sofiane Boufal
A player familiar to many Premier League fans from his time at Southampton, Moroccan trickster Sofiane Boufal is yet to make a big impact at Union St Gilloise, with just one start so far.
However, the supremely talented 31-year-old will surely show his quality soon, and we think he could make an impactful cameo from the bench.