Twente take on Lazio at the De Grolsch Veste in a Europa League Group Stage fixture on Thursday, 24 October. Read our Europa League predictions for the clash below.
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Twente vs Lazio prediction: Goals possible at both ends
Key Stats
- Ten of Twente’s last 13 matches in all competitions featured goals at both ends.
- BTTS also landed in ten of Lazio’s last 12 matches in all competitions.
- Twente scored one goal in four of their last five assignments.
- Twente have yet to lose a single game on home soil this season.
Correct score prediction: Twente 1-1 Lazio
Twente are a tough nut to crack in Enschede and three of their last five matches on home soil finished level at 1-1. Lazio might have to be content with a point when they visit the Netherlands on Thursday evening.
Pre-game odds and win probability: Lazio have a slight edge
- HOME: 17/10 (2.70) – 37%
- DRAW: 23/10 (3.30) – 30.3%
- AWAY: 8/5 (2.60) – 38.5%
*odds from Ladbrokes, subject to change
Twente drew 1-1 in both of their first two UEL matches against Man Utd and Fenerbahce and the Tukkers, who are 17/10 underdogs ahead of Thursday’s game, could be tough to beat again this week.
Lazio meanwhile, have won four of their last five matches, however, they have lost three of their last five tussles on the road, and they aren’t overly attractive at 8/5 in the match result markets. Head over to our football tips page for more of our latest Europa League predictions.
Most recent H2Hs: Clubs have met once before
Twente and Lazio have met on just one previous occasion, though that encounter back in 2021 was a friendly fixture that finished 1-0 in the Italians’ favour.
Europe Friendlies 07/08/21
FC Twente
Lazio
Twente preview: Trio sidelined for hosts
FC Twente will be without the services of Daan Rots, Younes Taha and Michael Sadilek on Thursday. Twente hit an injury-time equalizer in a 2-2 draw at RKC Waalwijk in the Eredivisie at the weekend.
Predicted lineup: Unnerstall (GK), Van Rooij, Hilgers, Bruns, Salah-Eddine, Regeer, Vlap, Van Wolfswinkel, Van Bergen, Steijn, Lammers
Netherlands Eredivisie 11/05/25
W
FC Utrecht
0
FC Twente
2
Netherlands Eredivisie 04/05/25
W
Sparta Rotterdam
0
FC Twente
2
Netherlands Eredivisie 24/04/25
L
PSV
3
FC Twente
1
Netherlands Eredivisie 13/04/25
D
PEC Zwolle
1
FC Twente
1
Netherlands Eredivisie 05/04/25
D
Fortuna Sittard
1
FC Twente
1
Lazio preview: Lazzari in the treatment room
Manuel Lazzari is injured and won't be involved on Thursday. Alessio Romagnoli is suspended domestically, though the defender is free to play in the Europa League this week. Lazio won their first two UEL matches against Dinamo Kiev (3-0) and Nice (4-1).
Predicted lineup: Provedel (GK), Marusic, Gila, Romagnoli, Tavares, Guendouzi, Rovella, Isaksen, Dia, Zaccagni, Castellanos
Italy Serie A 10/05/25
D
Juventus
1
Lazio
1
Italy Serie A 04/05/25
W
Empoli
0
Lazio
1
Italy Serie A 28/04/25
D
Parma
2
Lazio
2
Italy Serie A 23/04/25
W
Genoa
0
Lazio
2
UEFA Europa League 17/04/25
W
Bodo/Glimt
1
Lazio
3
Player to watch – Michel Vlap
Michel Vlap was Twente’s Man-of-the-Match in their 1-1 draw with Fenerbahce on matchday two, when he netted his team’s solitary goal to cap a fine display.

Vlap can be influential again
Vlap is an all-action performer for Twente in midfield and the 27-year-old has been averaging 1.50 tackles and 1.50 shots per game in the Europa League this season. Vlap has also been averaging 2.50 key passes, highlighting his more creative skillset, so expect him to be central to proceedings again against Lazio.