Tottenham will welcome Villarreal to the Tottenham Hotspur Stadium for their UEFA Champions League encounter on Tuesday, 16 September 2025.
View our free Tottenham vs Villarreal predictions below.
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Tottenham vs Villarreal predictions: One team to blank
Key stats
- At least one team failed to score in four of Villarreal's last five matches.
- Tottenham have kept three clean sheets in their last four games.
- Four of Villarreal's last five games went below the 2.5-goal threshold.
Correct score prediction: Tottenham 1-0 Villarreal
Tottenham have had a great start to their Premier League campaign, winning three of their four league games by at least a two-goal margin. Thomas Frank's men have been solid defensively, conceding only once in those four matches.
On the other hand, Villarreal's recent away results do not inspire much confidence. They have managed one win in their last eight away games across all competitions, failing to score in three of their last six.
Taking everything into account, we are leaning toward Spurs for the win.
Pre-game odds and win probability: Spurs are clear favourites
- HOME: 9/10 (1.90) – 52.6%
- DRAW: 13/5 (3.60) – 27.8%
- AWAY: 29/10 (3.90) – 25.6%
*Odds from Ladbrokes, subject to change
Ahead of this skirmish, Tottenham Hotspur are the expected winners at 9/10 (1.90). Teams with these odds generally have a 52.6% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Tottenham vs Villarreal predictions, as well as our Coral signup offer for this month.
Also, bearing in mind that fewer than three goals were scored in four of Villarreal's last five matches, under 2.5 total goals has an appealing look at 1/1 (2.00). That one has a 50% chance of landing.
Most recent H2Hs: First competitive encounter
Tottenham Hotspur's only meeting with Villarreal came in a friendly in July 2010, where Spurs suffered a humiliating 4-1 defeat. This will be the first competitive clash between these sides.
Tottenham Hotspur preview: Plagued by injuries
Coach Frank has several long-term injury absentees, including Radu Dragusin (ACL), James Maddison (ACL), and Dejan Kulusevski (knee).
In addition, Dane Scarlett (groin) and Kota Katai (foot) are ruled out of this meeting, while there is positive news around Dominic Solanke, as the former Liverpool forward could be fit enough to feature on Tuesday night.
Following an impressive debut last weekend, Xavi Simons is expected to start once again in the final third alongside Mathys Tel and Mohammed Kudus.
Predicted lineup: Vicario (GK), Spence, Van de Ven, Romero, Porro, Bergvall, Palhinha, Sarr, Simons, Tel & Kudus.
Last five matches
- West Ham 0-3 Tottenham
- Tottenham 0-1 Bournemouth
- Man City 0-2 Tottenham
- Tottenham 3-0 Burnley
- PSG 2-2 Tottenham (4-3 AP)
Villarreal preview: Eyeing their first away win of the season
Villarreal, on the other hand, will be without Willy Kambwala, Logan Costa and Pau La Torre due to injury, while veteran forward Gerard Moreno remains a doubt for the trip to London.
Also, former Leicester City man Ayoze Perez is yet to feature this season for the visitors due to an adductor injury, and he remains doubtful for this match.
Predicted lineup: Junior (GK), Mourino, Foyth, Veiga, Cardona, Buchanan, Partey, Gueye, Moleiro, Pepe & Mikautadze.
Last five matches
- Atletico Madrid 2-0 Villarreal
- Celta Vigo 1-1 Villarreal
- Villarreal 5-0 Girona
- Villarreal 2-0 Real Oviedo
- Villarreal 0-2 Aston Villa
Player to watch: Lucas Bergvall
Lucas Bergvall put in a man-of-the-match performance last weekend, registering a goal and an assist in Tottenham's 3-0 victory at West Ham United. The former Djurgardens midfielder will look to score in back-to-back games for the first time in his career.