Tottenham Hotspur vs Atletico Madrid prediction, preview & betting tips – 18/03/2026
Atletico Madrid won two of two encounters between these teams in the last decade. - Photo by IMAGO/Zuma Press Wire
🔥 Our Hot tip

HT Atletico Madrid to win

Spurs trailed at the half-time break in seven of their last eight matches.

Tottenham Hotspur will have the Herculean task of overturning a massive deficit when they host Atletico Madrid in the second leg of their UEFA Champions League round of 16 tie on Wednesday.

Spurs, who are currently on an eight-match winless streak across all competitions, suffered a 5-2 defeat last week in Madrid.

Atletico, meanwhile, will set their sights on extending their winning streak to four games.

Read our Tottenham Hotspur vs Atletico Madrid prediction, preview and betting tips. You can also check out our Today's betting tips page for more of our expert predictions.

Tottenham Hotspur vs Atletico Madrid key stats

  • Six of Tottenham’s last eight matches produced at least five cards.
  • Spurs conceded first in seven of their last eight games.
  • Atletico Madrid opened the scoring in five of their last six matches.

Tottenham Hotspur vs Atletico Madrid preview: Can depleted Spurs make history?

Tottenham Hotspur vs Atletico Madrid Tale of the Tape
Tottenham Hotspur vs Atletico Madrid
16th (Premier League)Position3rd (La Liga)
30Points57
40Goals For47
47Goals Against25
7Clean Sheets12
20thHome Rank2nd
9thAway Rank6th

It is worth mentioning that Atletico Madrid have never squandered a three-goal advantage in European competition.

The most significant collapse of the Diego Simeone era came in 2019, when they travelled to Turin with a 2-0 lead over Juventus, only to be sent crashing out by a clinical Cristiano Ronaldo hat-trick.

🔍 Whispers Insight

Tottenham lost their last four two-legged ties in UEFA competition.

Interestingly, Tottenham’s greatest-ever European escape came during that same 2018/19 season. While Atletico were crumbling in Turin, Spurs were busy producing the 'Miracle of Amsterdam' to overturn a three-goal aggregate deficit against Ajax.

Coincidentally, that journey ended in a final played at the Wanda Metropolitano - the very same stadium, now known as the Riyadh Air Metropolitano, where they suffered last week’s 5-2 humbling.

Tottenham are struggling with injuries, with most of the team's midfielders on the sidelines at the moment. In midfield, Spurs are currently missing James Maddison, Dejan Kulusevski, Mohammed Kudus, Lucas Bergvall, Joao Palhinha, Yves Bissouma, and Rodrigo Bentancur.

🔍 Whispers Insight

Spurs are unbeaten in their last 24 UEFA home matches (W20 D4), and they have won all four this season without conceding a goal.

In attack, the hosts will have to do without Wilson Odobert due to injury, and Richarlison through suspension, while defenders Destiny Udogie and Cristian Romero are also unavailable with injury problems.

Despite the many injury challenges in the team, Igor Tudor’s available troops are expected to give their all in front of the home supporters on Wednesday night.

Similarly, Atletico Madrid have some injury problems, with first-choice goalkeeper Jan Oblak recently joining Pablo Barrios and Rodrigo Mendoza on the sidelines.

Los Colchoneros did much of the work in the tie last Tuesday, but the visitors are not expected to sit back and watch a highly depleted Tottenham Hotspur dictate the tempo of the game. Atleti will be coming to London to get the job done, with their forwards eager to get their names on the scoresheet.

Tottenham Hotspur vs Atletico Madrid form guide & betting tips

Last 5 Form Guide (all competitions)
Tottenham Hotspur vs Atletico Madrid
L-L-L-L-D Form W-L-W-W-W
6Goals For10
15Goals Against7
L-W-W-W-LChampions League formD-L-D-W-W

Whispers Predicts: Tottenham Hotspur 2-3 Atletico Madrid

At 2.63, Tottenham Hotspur are slightly favoured by the bookies ahead of this clash.

However, Tudor's side have a long list of injuries, and considering their eight-game winless streak, we fancy Atletico Madrid at 2.64.

Also, while Atletico Madrid drew first blood in five of their last six games, Spurs conceded first in seven of their last eight matches.

On that note, Atletico Madrid to score first can be backed at 1.90.

📈 Whispers' Tips

> BTTS - Yes at 1.62 | Likelihood: Probable

> Over 3.5 goals at 2.80 | Likelihood: Possible

> Match result - Atletico Madrid at 2.64 | Likelihood: Possible

> Atletico Madrid & BTTS - Yes at 4.50 | Likelihood: Possible

> Correct score: 1-1 at 27.00 | Likelihood: Outsider


Kelechi is a huge sports fan with over 10 years of betting experience. He has written for a few publications like Afrik-Foot, What Are The Odds, Mighty Tips and Pundit Feed