St Pauli vs Bayer Leverkusen prediction, odds & betting tips 27/09/25
Kasper Hjulmand giving instructions to Malik Tillman - photo by Imago
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Bayer Leverkusen to win

Leverkusen are undefeated in their last six matches against St Pauli

Bayer Leverkusen will be looking to pick up their first win away from home when they face St Pauli in the Bundesliga clash on Saturday, 27 September at Millerntor-Stadion.

Die Werkself find themselves 11th in the league table with just five points, whereas St Pauli are fifth in the league with seven points from four games.

Check out our St Pauli vs Bayer Leverkusen prediction below.

St Pauli vs Bayer Leverkusen prediction: Will Die Schwarzroten pick up their second win?

Key stats

  • Leverkusen are undefeated in their last games in all competitions.
  • St Pauli have not lost at home this season.
  • The visitors have yet to win a game in 2025-26 away from home.

Correct score prediction: St Pauli 1-2 Bayer Leverkusen

The home side are heading into this game on the back of a 2-0 defeat against Stuttgart. St Pauli have scored in all their home games, including a 3-3 thriller against Borussia Dortmund in the opening league match.

Leverkusen have shown signs of revival under Kasper Hjulmand since the sacking of Erik ten Hag, and might grab a win after an encouraging 2-2 draw against FC Copenhagen in the Champions League last week.

Pre-game odds and win probability: Leverkusen favourite with the bookmakers

  • HOME: 21/10 (3.1) – 32.3%
  • DRAW: 5/2 (3.5) – 28.6%
  • AWAY: 6/5 (2.2) – 45.5%

*Odds from Ladbrokes, subject to change 

As shown by the implied probabilities, Leverkusen are slight favourites to pick up all three points from this fixture.

Leverkusen finished second in the Bundesliga last season and lifted the league trophy for the first time in their history in the 2023-24 season under Xabi Alonso. Despite losing some key players, they have a strong squad capable of finishing within the top three this season.

Don’t forget to check out more of our best betting tips if you enjoyed our tips for this match.

Most recent H2Hs: Bayer Leverkusen have upper hand

Leverkusen are undefeated against St Pauli in their last six meetings, which should give them a psychological boost ahead of this fixture.

Last season, Xabi Alonso's side drew 1-1 at the Millerntor-Stadion and earned a 2-1 victory at their home turf in this fixture.

Germany Bundesliga I 20/04/25

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Germany Bundesliga I 07/12/24

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Club Friendly List 04/09/14

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St Pauli preview: Can they bounce back?

Kiezkicker finished 14th in the league last season with 32 points, and they will aim to do better than that this term.

Under Alexander Blessin, they have made a strong start to the season, winning back-to-back games against Hamburg and Augsburg before losing to Stuttgart in their previous game.

Predicted lineup: Vasilj, Dzwigala, Smith, Wahl, Oppie, Fujita, Sands, Saliakas, Sinani, Lage & Hountondji

Last five matches 

  • Stuttgart 2-0 St Pauli
  • St Pauli 2-1 Augsburg
  • Hamburg 0-2 St Pauli
  • St Pauli 3-3 Borussia Dortmund
  • Eintracht Norderstedt 0-0 St Pauli (St Pauli won 3-2 on penalties)

Bayer Leverkusen preview: Search for second league win

Leverkusen sporting director Simon Rolfes admitted that hiring Ten Hag was a mistake, and the club made an even bigger error by allowing him to continue. The Dutchman was sacked after just two league games, which has never happened in the club's history before.

Hjulmand guided Denmark to the European Championship semi-finals in 2021, and Leverkusen have shown signs of revival under him.

Robert Andrich and Ezequiel Fernandez should be back in the squad after serving a one-match suspension.

Predicted lineup: Flekken, Tapsoba, Bade, Quansah, Grimaldo, Garcia, Andrich, Vazquez, Tillman, Maza & Schick

Last five matches 

  • Leverkusen 1-1 Monchengladbach
  • Copenhagen 2-2 Leverkusen
  • Leverkusen 3-1 Frankfurt
  • Bremen 3-3 Leverkusen
  • Leverkusen 1-2 Hoffenheim

Player to watch: Alejandro Grimaldo

The 30-year-old has been brilliant this season for Leverkusen, having already scored three goals in all competitions.

The Spaniard scored a brace in the 3-1 win over Frankfurt and has registered one assist against Hoffenheim.

St Pauli vs Bayer Leverkusen prediction
Alejandro Grimaldo in action for Bayer Leverkusen – photo by Imago
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Saikat is a freelance Sports Journalist with over ten years of experience covering football (and other sports) for various publications including GRV Media, Rocket Sports Network, Breaking Media, and Football Whispers. Saikat also has a keen interest in F1, cricket, and tennis and has taken face to face interviews of footballers such as Emile Heskey and Robbie Fowler.