Southampton vs Man City prediction, odds & betting tips – 10/05/2025

Relegated Southampton host top-four chasers Man City at St. Mary’s Stadium in England’s Premier League on Saturday, 10 May. Read our Premier League predictions for the match below.

Southampton vs Man City prediction: Don’t expect fireworks on the south coast

Key Stats

• Southampton have lost 11 of their last 12 Premier League home games.
• Man City have won five of their last six fixtures in the Premier League.
• Southampton have failed to score in 14 different Premier League matches this season.
• Only two clubs have collected more cards than Southampton (89) in the Premier League this term.

Correct score prediction: Southampton 0-1 Man City

Man City ground out a 1-0 win over Southampton when the teams last met in October and a similar result could be worth backing here. City have scored only four goals in their last five away games combined, so expect margins to be slim.

Pre-game odds and win probability: Saints given little chance

• HOME: 10/1 (11.00) – 9.1%
• DRAW: 6/1 (7.00) – 14.3%
• AWAY: 2/9 (1.22) – 81.8%

*odds from Ladbrokes, subject to change

Southampton were beaten 2-0 by fellow bottom-three outfit Leicester last weekend and the sorry Saints have been given just a 9.1% chance of bouncing back to beat City here.

Man City’s 1-0 win over Wolves last time out has put them in the driving seat for a top-four finish and they have an 81.8% chance of seeing off a poor Southampton side on the south coast. Read more of our football predictions and Premier League analysis on our dedicated page.

Most recent H2Hs: Man City have been dominant

Man City have won four of their last five meetings with Southampton in league and cup. They eased to a 4-1 win when they last visited St. Mary’s Stadium back in April 2023.

England Premier League 26/10/24

Man City

1

Southampton

0

England Premier League 08/04/23

Southampton

1

Man City

4

England EFL Cup 11/01/23

Southampton

2

Man City

0

England Premier League 08/10/22

Man City

4

Southampton

0

England FA Cup 20/03/22

Southampton

1

Man City

4

Southampton preview: Saints at close to full strength

Southampton have few injury issues to contend with ahead of the weekend and interim boss Simon Rusk has the “luxury” of a selection headache in several different positions as a result. Wonderkid Tyler Dibling will be among those hoping to start.

Predicted lineup: Ramsdale (GK), Harwood-Bellis, Bednarek, Stephens, Walker-Peters, Downes, Ugochukwu, Manning, Fernandes, Sulemana, Stewart

England Premier League 10/05/25

D

Man City

0

Southampton

0

England Premier League 03/05/25

L

Leicester

2

Southampton

0

England Premier League 26/04/25

L

Fulham

2

Southampton

1

England Premier League 19/04/25

D

West Ham

1

Southampton

1

England Premier League 12/04/25

L

Aston Villa

3

Southampton

0

Man City preview: Haaland could get minutes

Nathan Ake, Rodri and John Stones remain sidelined for City. Erling Haaland was fit enough to earn a place on the bench against Wolves and the Norwegian could get minutes here. Kevin De Bruyne could continue in the false nine position to start with, however.

Predicted lineup: Ederson (GK), Lewis, Dias, Gvardiol, O'Reilly, Kovacic, Gundogan, Foden, McAtee, Doku, De Bruyne

England Premier League 10/05/25

D

Southampton

0

Man City

0

England Premier League 02/05/25

W

Wolverhampton

0

Man City

1

England FA Cup 27/04/25

W

Nottm Forest

0

Man City

2

England Premier League 22/04/25

W

Aston Villa

1

Man City

2

England Premier League 19/04/25

W

Everton

0

Man City

2

Player to watch – Lesley Ugochukwu

Lesley Ugochukwu has been a shining light in what was been a miserable Premier League campaign for bottom club Southampton and the promising midfielder will be out to impress again against Man City.

Ugochukwu is an expert ball carrier

Ugochukwu, who is on loan with the Saints from Chelsea, has a 69.2% take-on success rate in the Premier League this season, which is the best rate of any midfielder in the competition, so it’s easy to see why the 21-year-old has been tipped for a first-team breakthrough at Stamford Bridge next term.