This weekend, Sassuolo will take on Roma at the Mapei Stadium in Reggio Emilia on Sunday in the Serie A as both teams look to bounce back from their disappointing results last weekend.
The Neroverdi have started the season on a good note, with the team dominant at home entering this game. Despite their form, they failed to build on their two-game winning streak and were held to a 0-0 draw against Lecce.
The Giallorossi have had a good run of wins in their last five games. However, they lost 1-0 to Inter Milan last weekend, which has seen them drop to fourth place in the league table. They also lost 2-1 at home in their UEFA Europa League game on Thursday night.
Read our Sassuolo vs Roma predictions and preview to find out, but remember to also check our other Serie A predictions.
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Sassuolo vs Roma prediction: Visitors to win by narrow margin
Key statistics
- Roma defeated Sassuolo at their home ground in their last meeting.
- The Giallorossi won by a 2-1 scoreline in their last trip to the Neroverdi.
- Four of their last five games have seen over 2.5 goals being scored.
Correct score prediction: Sassuolo 1-2 Roma
Both teams have held their own this season, Sassuolo currently having four wins in their last five home games and Roma with five straight away wins in all competitions.
Given the visitors' performance this season, we expect them to edge this encounter by a narrow margin, which is why we are predicting a 1-2 victory for them. Although the home side has often caused problems for the visitors, Roma's attacking options will provide the necessary edge.
Pre-match odds and win probability: AS Roma are the favourites
- Home: 16/5 (4.20) – 23.8%
- Draw: 5/2 (3.50) – 28.6%
- Away: 5/6 (1.83) – 54.6%
*Odds provided by Ladbrokes. Subject to change.*
The Giallorossi have been given favourable odds by the bookmakers in this clash. They have a 54.6% chance of victory at 1.83 odds. The Neroverdi, priced at 4.20, hold a 23.8% chance to win, while a draw at 3.50 represents a 28.6% probability. The odds suggest Roma are expected to dominate, though Sassuolo could still pose a challenge on home turf.
Most recent head-to-head: Roma edges previous meetings
The last five Serie A fixtures between Sassuolo and Roma show a clear advantage for the away team. Roma have secured two back-to-back victories against Sassuolo in their last meetings and the Neroverdi have only one win with two draws between them. The most recent league match between the two sides was a narrow 1-0 victory for Roma in March 2024.
Italy Serie A 17/03/24
Roma
Sassuolo
Italy Serie A 03/12/23
Sassuolo
Roma
Italy Serie A 12/03/23
Roma
Sassuolo
Italy Serie A 09/11/22
Sassuolo
Roma
Italy Serie A 13/02/22
Sassuolo
Roma
After reviewing our key Sassuolo vs Roma predictions, be sure to visit our website for the remaining football betting tips today.
Sassuolo preview: Few players set to miss clash
Fabio Grosso’s team will be monitoring Daniel Boloca and Tarik Muharemovic, who are both dealing with physical discomfort. Edoardo Pieragnolo is also a doubt for the upcoming fixture as he recovers from a similar issue.
Predicted lineup: Muric (GK), Walukiewicz, Romagna, Idzes, Doig, Vranckx, Matic, Thorstvedt, Berardi, Lauriente & Pinamonti
Last five fixtures
- 18.10.25 – Lecce 0 – 0 Sassuolo
- 03.10.25 – Verona 0 – 1 Sassuolo
- 28.09.25 – Sassuolo 3 – 1 Udinese
- 24.09.25 – Como 3 – 0 Sassuolo
- 21.09.25 – Inter 2 – 1 Sassuolo
Roma preview: Multiple injury trouble in the team
Roma manager Gian Piero Gasperini will have to set his team without Edoardo Bove, who is sidelined due to heart problems. Angelino is also unavailable as he recovers from a virus, with his return expected in November. Meanwhile, Jan Ziolkowski and Kouadio Kone are both doubtful for the upcoming fixture as they continue to deal with knee and muscle injuries, respectively.
Predicted lineup: Svilar (GK), Ghilardi, Mancini, Hermoso, Celik, El Aynaoui, Pisilli, Wesley, Dybala, Soule & Dovbyk
Last five fixtures
- 23.10.25 – AS Roma 1 – 2 Plzen
- 18.10.25 – AS Roma 0 – 1 Inter
- 05.10.25 – Fiorentina 1 – 2 AS Roma
- 02.10.25 – AS Roma 0 – 1 Lille
- 28.09.25 – AS Roma 2 – 0 Verona
Player to watch: Matias Soule
One player who could cause major problems for Sassuolo is Matias Soule. The Argentine has been in impressive form this season, registering three goals and two assists in all competitions.
His sharp movement and eye for goal make him a constant danger inside the box and the Neroverdi’s defence will need to stay alert to prevent him from finding space or latching onto loose balls in dangerous areas.