Three points will be at stake when Sassuolo host Pisa at Mapei Stadium in the 12th round of Serie A on Monday, 24 November 2025.
View our free Sassuolo vs Pisa predictions below.
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Sassuolo vs Pisa predictions: Goals at both ends
Key stats
- Both teams were on the scoresheet in four of Pisa's last six away games across all competitions.
- Pisa are still hunting for their first away win of the season.
- Sassuolo were victorious in Pisa's previous two trips to this stadium.
Correct score prediction: Sassuolo 2-1 Pisa
Although Pisa defeated Cremonese before the international break, that was their first win in 12 matches across all competitions this season. Sassuolo have fared much better than their hosts, winning five of 11 Serie A games so far.
Keeping in mind that Pisa have lost two of two previous trips to this stadium, we are confident that Sassuolo will claim all the spoils after all is said and done.
Pre-game odds and win probability: Pisa up against it
- HOME: 11/10 (2.10) – 47.6%
- DRAW: 11/5 (3.20) – 31.2%
- AWAY: 27/10 (3.70) – 27%
*Odds from Ladbrokes, subject to change
Despite being the clear underdogs, Sassuolo secured a comfortable 3-0 victory away at Atalanta in their previous outing. With a 5-1-5 win-draw-loss record, Fabio Grosso’s men are eighth in Serie A.
On the other hand, 16th-placed Pisa earned their first win of the season last time out, halting a run of four consecutive draws and 11 straight matches without a win. They will now set their sights on their first away win of this campaign.
Ahead of this skirmish, Sassuolo are the expected winners at 11/10 (2.10). Teams with these odds generally have a 47.6% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Sassuolo vs Pisa predictions.
Also, Pisa have played five away games in Serie A this season, and both teams scored in four of them. For this reason, BTTS – Yes has an appealing look at 19/20 (1.95). That one has a 51.3% chance of landing.
Most recent H2Hs: Sassuolo to keep perfect home record intact?
There have been four previous meetings between these teams, and Sassuolo narrowly lead the H2H with a 2-1-1 win-draw-loss record. It is important to note, however, that they have won two of two home games against Pisa.
Italy Serie B 01/03/25
Sassuolo
Pisa
Italy Serie B 26/12/24
Pisa
Sassuolo
Sassuolo preview: Plagued by injuries
Head coach Fabio Grosso will not be able to rely on five players for this game due to injury, including Filippo Romagna, Daniel Boloca, Laurs Skjellerup, Edoardo Pieragnolo, and Cristian Volpato.
Predicted lineup: Muric (GK), Walukiewicz, Idzes, Muharemovic, Doig, Vranckx, Matic, Kone, Berardi, Pinamonti & Lauriente.
Last five matches
- Atalanta 0-3 Sassuolo
- Sassuolo 0-0 Genoa
- Cagliari 1-2 Sassuolo
- Sassuolo 0-1 AS Roma
- Lecce 0-0 Sassuolo
Pisa preview: Eyeing their first away win
In like manner, Pisa are suffering injury tribulations ahead of this clash, as four key members of the squad are ruled out due to various health problems, including summer signing Calvin Stengs, Tomas Esteves, Mateus Lusuardi, and Nigerian youngster Ebenezer Akinsanmiro, while Juventus great Juan Cuadrado is deemed touch and go.
Predicted lineup: Semper (GK), Canestrelli, Albiol, Caracciolo, Toure, Marin, Aebischer, Tramoni, Leris, Moreo & Nzola.
Last five matches
- Pisa 1-0 Cremonese
- Torino 2-2 Pisa
- Pisa 0-0 Lazio
- AC Milan 2-2 Pisa
- Pisa 0-0 Verona
Player to watch: Domenico Berardi
Sassuolo have scored seven goals in Serie A this season, and Domenico Berardi was directly involved in seven of them. The former Juventus midfielder, who leads the team in both goals and assists, will be called upon to provide goals on Monday night.