An interesting fixture is on the cards as last season's Serie B winners host the reigning Serie A champions at Mapei Stadium on Saturday, 23 August 2025.
View our free Sassuolo vs Napoli predictions below.
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Sassuolo vs Napoli predictions: Visitors to claim all the spoils
Key stats
- Napoli won their last five encounters with Sassuolo.
- Five of the last seven clashes between these teams went above the 2.5-goal threshold.
- Both teams found the net in five of Napoli's last six games.
Correct score prediction: Sassuolo 1-3 Napoli
To be fair, Sassuolo are brimming with confidence after stringing together a five-match unbeaten run. However, the Serie B champions have a poor track record against Napoli, having lost each of the last five skirmishes between these outfits.
Keeping in mind that Napoli are currently on a three-game winning run, we are confident that the Partenopei will kick off their title defence with a victory on the road.
Pre-game odds and win probability: Napoli are overwhelming favourites
- HOME: 5/1 (6.00) – 16.7%
- DRAW: 4/1 (5.00) – 20%
- AWAY: 4/7 (1.57) – 63.6%
*Odds from Ladbrokes, subject to change
Ahead of this encounter, Napoli are the expected winners at 4/7 (1.57). Teams with these odds generally have a 63.6% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Sassuolo vs Napoli predictions.
We have also established that five of Napoli's last six games produced goals at both ends. On that note, BTTS – Yes has an appealing look at 1/1 (2.00). That one has a 50% chance of landing.
Most recent H2Hs: Business as usual for Napoli?
Napoli cruised to a comfortable 6-1 victory in the last encounter between these teams. They have won five consecutive meetings with Sassuolo and are unbeaten in their last seven skirmishes.
Interestingly, the last time Sassuolo beat Napoli at home was on 23 August 2015, exactly 10 years prior to the date of this fixture.
Italy Serie A 28/02/24
Sassuolo
Napoli
Italy Serie A 27/08/23
Napoli
Sassuolo
Italy Serie A 17/02/23
Sassuolo
Napoli
Italy Serie A 29/10/22
Napoli
Sassuolo
Italy Serie A 30/04/22
Napoli
Sassuolo
Sassuolo preview: A couple of absentees
Following their relegation from Serie A in the 2023-24 campaign, Sassuolo made an immediate return to the Italian top flight as they clinched the Serie B title last season.
The Black and Greens will aim to start the campaign on a bright note at home against the reigning champions. With captain Domenico Berardi as the star man in the squad, and other standout players such as Andrea Pinamonti and Armand Lauriente, as well as new signings Alieu Fadera and Ismael Kone, the hosts should pose some threat against Napoli.
On the injury front, Kristian Thorstvedt and Laurs Skjellerup are ruled out this weekend due to injury.
Predicted lineup: Turati (GK), Walukiewicz, Romagna, Muharemovic, Doig, Kone, Boloca, Ghion, Berardi, Lauriente & Fadera.
Italy Serie B 13/05/25
L
Frosinone
1
Sassuolo
0
Italy Serie B 09/05/25
L
Catanzaro
2
Sassuolo
0
Italy Serie B 04/05/25
D
Cremonese
1
Sassuolo
1
Italy Serie B 01/05/25
W
Carrarese
0
Sassuolo
2
Italy Serie B 25/04/25
W
Cesena
0
Sassuolo
2
Napoli preview: Looking to extend their winning streak
With Antonio Conte at the helm, Napoli made the most of their lack of European football last season by clinching their second Scudetto in three years and their fourth in history.
Scott McTominay was the star of the show last campaign, and with the addition of Kevin De Bruyne on a free transfer from Manchester City, as well as Sam Beukema and Lorenzo Lucca, Napoli are highly placed to defend their title this season.
Italian striker Lorenzo Lucca is expected to make his competitive debut this weekend for Napoli, as Romelu Lukaku has been ruled out due to a thigh injury.
Predicted lineup: Meret (GK), Di Lorenzo, Rrahmani, Buongiorno, Mathias Olivera, De Bruyne, Lobotka, McTominay, Politano, Lucca & Neres.
Italy Serie A 11/05/25
D
Genoa
2
Napoli
2
Italy Serie A 03/05/25
W
Lecce
0
Napoli
1
Italy Serie A 27/04/25
W
Torino
0
Napoli
2
Italy Serie A 19/04/25
W
Monza
0
Napoli
1
Italy Serie A 14/04/25
W
Empoli
0
Napoli
3
Player to watch: Scott McTominay
Scott McTominay has put in some impressive performances for Napoli in recent months, scoring seven goals and providing three assists in his last 11 appearances. The former Manchester United player will be called upon to provide goals this weekend.