Sassuolo vs Lazio prediction, preview & betting tips – 27/10/2026
Lazio won 2-1 in their last meeting. (Photo by Icon Sport/ActionPlus)
🔥 Our Hot tip

Lazio to win or draw at half-time

Lazio are the only team yet to trail a Serie A match at half-time this season (HT: W4, D4).

As one of the six Serie A sides undefeated at home, Sassuolo welcome Gennaro Gattuso’s unbeaten Lazio outfit to Mapei Stadium – Citta del Tricolore on Tuesday, 27 October.

The Biancocelesti are enjoying one of their best-ever starts to a top-flight campaign, while Sassuolo are on a four-match winless run.

Read our prediction, preview and betting tips – powered by the latest bet365 sign-up offer – for the game below, and make sure to check out our today's betting tips page for more of our expert predictions.

Sassuolo vs Lazio key stats

  • Sassuolo are on a two-match losing streak, conceding six along the way.
  • The Neroverdi have conceded four goals in three home games.
  • Lazio have the best away defence this term, having conceded only one in four outings.
  • The Biancocelesti are on a four-match winning run in Serie A.

Sassuolo vs Lazio preview: Biancocelesti inflict first home defeat for Neroverdi

Sassuolo vs Lazio — Tale of the Tape

Sassuolo vs Lazio
14thPosition2nd
8Points22
12Goals For16
16Goals Against5
0Clean Sheets4
7thHome / Away Rank1st

Since a heroic 3-2 win over Juventus in mid-September, Sassuolo have been bleak at best, losing three and drawing one.

That one draw came against AC Milan, after which back-to-back defeats to Frosinone and Como have seen them sum closer to the relegation zone.

At home, Sassuolo have been impressive this campaign, but haven’t kept a league clean sheet since early May.

Alberto Aquilani has five players sidelined: Daniel Boloca, Jay Idzes, Fedde Leysen, Yeferson Paz and Ismael Kone.

As for Lazio, Gattuso is missing four players. They are Adam Marusic, Nicolo Rovella, Albert Gudmundsson and Alessio Furlanetto.

Lazio have been at their best since the campaign began, with 22 points from eight games their best return at this stage since their 1999/2000 Scudetto-winning season.

Consistent scorers with three goals in two of their last three games, and only five goals conceded so far, Lazio are breathing down the necks of reigning champions Inter Milan.

Away from home, the Biancocelesti are on a four-match winning streak. The last time they tasted a loss on the road was in the Derby della Capitale against Roma on the final day of the previous season.

Sassuolo vs Lazio form guide & betting tips

Sassuolo vs Lazio — Last 5 Form Guide
Sassuolo vs Lazio
WLDLL
Last five
WDWWW
7Goals For11
11Goals Against5
WLDLL
Serie A form
DWWWW

Whispers predicts: Sassuolo 1-2 Lazio

According to Bet365, backing double chance i.e. Lazio or Draw and BTTS – Yes at 21/20 (2.05) offers significant value. Lazio haven’t lost a single game this campaign, while Sassuolo are also unbeaten but on home turf.

BTTS – Yes as a standalone bet at 6/10 (1.60) also carries value. Sassuolo’s all eight top-flight matches this term saw both teams score.

Four of Lazio’s last five away league games produced at least ten corners. Over 9.5 total corners at 5/4 (2.25) is worth keeping tabs on.

Lazio to win or draw at half-time at 1/1 (2.00) is worth the consideration as well, given Lazio are the only team yet to trail a Serie A match at half-time this season (HT: W4, D4).

📈 Sassuolo vs Lazio — Whispers' Tips

> Lazio or Draw and BTTS – Yes at 21/20 (2.05) | Likelihood: Possible

> BTTS – Yes at 6/10 (1.60) | Likelihood: Probable

> Over 9.5 total corners at 5/4 (2.25) | Likelihood: Likely

> Lazio to win or draw at half-time at 1/1 (2.00) | Likelihood: Probable


With a passport full of stories, Akhil has journeyed across Europe and beyond, immersed in the fabric of the beautiful game. From covering thrilling Milan derby nights at San Siro as a live match analyst to uncovering hidden talents in the Benelux region as a scout, his versatile and hybrid background allows him to deliver clear, engaging narratives that capture football's essence.