Sassuolo will host the league leaders, Inter Milan, at the MAPEI Stadium – Citta del Tricolore this Sunday, with the home side hoping to disrupt the momentum of the current table toppers.
Sassuolo closed out January with a 3–1 victory over Pisa, securing back-to-back wins and reinforcing their comfortable mid-table standing in their first season back in Serie A.
Fabio Grosso’s side will be aiming for a third straight league win for the first time since March 2023, a run that would also mark their first set of three consecutive victories across all competitions this season.
However, achieving that on home soil may prove challenging, as the Neroverdi have claimed only two wins in their last eight league matches at Mapei Stadium, following a strong start to the campaign that saw three victories from their opening four home fixtures.
Conversely, Inter continued their impressive season with a hard-fought 2–1 win over Torino in the Coppa Italia on Wednesday, booking a place in the semi-finals for the sixth time in seven seasons.
The Nerazzurri sit five points clear at the top of Serie A, having won 10 of their last 11 league games, and they could extend that advantage with another victory this weekend.
Their dominance is particularly striking on the road, where Inter have now secured seven consecutive away wins in the league, the third-longest such run in the club’s top-flight history.
Read our Sassuolo vs Inter Milan predictions and preview to find out, but remember to also check our other Serie A predictions.
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Sassuolo vs Inter Milan prediction: Away team to get a narrow win
Key statistics
- Inter Milan have scored two or more goals in three of their last five away games.
- Inter have won all their last five away games in all competitions.
- Three of their last five encounters have had BTTS being scored.
Correct score prediction: Sassuolo 1-2 Inter Milan
We expect a very competitive encounter at the MAPEI Stadium, where the home side often delivers their best performances against the elite clubs of the division. We predict a 2-1 victory for the visitors because of their form in the 2025/26 season.
Although the hosts have a consistent habit of scoring against the top sides, the tactical depth and quality of the visitors should allow them to secure a narrow win. We believe the superior quality of Inter’s team will prove decisive in the final stages of the game.
Pre-match odds and win probability: Inter Milan strongly favoured
- Home: 11/2 (6.50) – 15.4%
- Draw: 7/2 (4.50) – 22.2%
- Away: 10/21 (1.48) – 67.7%
*Odds provided by Ladbrokes. Subject to change.*
The odds point clearly in Inter Milan’s direction ahead of this clash, with the visitors priced at just 1.48, implying a dominant 67.7% chance of victory. That reflects Inter’s superior form and overall quality, even away from home.
Sassuolo are seen as outsiders, with odds of 6.50 translating to only a 15.4% probability of a home win, highlighting the scale of the task facing them.
The draw sits in between at 4.50 (22.2%), suggesting it’s considered more likely than a Sassuolo upset but still far from the most expected outcome.
Overall, the odds suggest a one-sided contest on paper, with Inter expected to control proceedings unless Sassuolo can significantly outperform expectations.
Most recent head-to-head: Inter with slight advantage
Our records show that in the last five competitive meetings between these two clubs, Inter have managed to have a slight edge against Sassuolo. They have secured three wins, while Sassuolo have managed two victories.
The most recent clash took place in September 2025, when the Nerazzurri claimed a 2-1 home win to avenge a 1-0 loss at the MAPEI Stadium in May 2024.
In late 2023, the Neroverdi produced a surprising 2-1 victory at San Siro, but Inter Milan responded with a 4-2 win earlier that year and a 2-1 success in late 2022.
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After reviewing our key Sassuolo vs Inter Milan predictions, be sure to visit our website for the remaining football betting tips today.
Sassuolo preview: Rotation over, but absentees remain
Once again, long-term absentees Edoardo Pieragnolo and Fali Cande will miss out through injury, while Daniel Boloca remains a doubt as he continues to recover from a knee problem.
Predicted lineup: Muric (GK), Walukiewicz, Idzes, Muharemovic, Doig, Thorstvedt, Matic, Kone, Berardi, Pinamonti & Lauriente
Last five fixtures
- 31.01.26 – Pisa 1–3 Sassuolo
- 25.01.26 – Sassuolo 1–0 Cremonese
- 17.01.26 – Napoli 1–0 Sassuolo
- 10.01.26 – AS Roma 2–0 Sassuolo
- 06.01.26 – Sassuolo 0–3 Juventus
Inter Milan preview: Injury concerns persist
Cristian Chivu is expected to revert to a stronger, more familiar lineup after rotating heavily against Torino in the Coppa Italia. However, Inter will still be without several key starters, as Denzel Dumfries, Hakan Calhanoglu and Nicolo Barella all remain unavailable.
There is some encouragement for the visitors, with Carlos Augusto set to return after missing the last two matches, giving Chivu an added option on the left flank.
Predicted lineup: Sommer (GK), Bisseck, Akanji, Bastoni, Henrique, Sucic, Zielinski, Mkhitaryan, Dimarco, Thuram & Martinez
Last five fixtures
- 04.02.26 – Inter 2–1 Torino
- 01.02.26 – Cremonese 0–2 Inter
- 28.01.26 – Dortmund 0–2 Inter
- 23.01.26 – Inter 6–2 Pisa
- 20.01.26 – Inter 1–3 Arsenal
Player to watch: Domenico Berardi
Domenico Berardi has been a key player for Sassuolo and he is currently their top scorer in Serie A this season. The forward has recorded five goals and three assists during the 2025/2026 campaign and could also get on the scoresheet against Inter.
He has consistently been involved in the final third and was a key presence in the recent victory over Pisa, scoring in the game. We expect him to lead the offensive efforts for the home side as they seek to cause an upset against the title challengers, Inter.