All eyes will be on Snapdragon Stadium as San Diego FC and Los Angeles Galaxy battle for three valuable points on Saturday, 24 May 2025.
View our free San Diego vs LA Galaxy predictions below.
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San Diego vs LA Galaxy predictions: Goals expected to flow
Key stats
- At least four goals were scored in four of LA Galaxy’s last five matches.
- Galaxy are still in the hunt for their first win of the season.
- While San Diego drew first blood in four of their last five games, LA Galaxy conceded first in seven of their last nine matches.
Correct score prediction: San Diego 3-1 LA Galaxy
Not only are LA Galaxy on a 13-match winless streak across all competitions, but they have also suffered five defeats in their last six games, conceding 18 goals in the process.
San Diego, on the other hand, are currently on a four-match unbeaten run (W3, D1). They won the reverse fixture on the road and should be able to complete the sweep this weekend.
Pre-game odds and win probability: San Diego are clear favourites
- HOME: 11/20 (1.55) – 64.5%
- DRAW: 3/1 (4.00) – 25%
- AWAY: 18/5 (4.60) – 21.7%
*Odds from Ladbrokes, subject to change
San Diego FC’s three-match winning run ended with a goalless draw with Sporting KC last weekend.
Mikey Varas’ men have been able to rely on their solid defence, keeping three clean sheets in their last four games.
Unlike their opponents, Los Angeles Galaxy have not had too much trouble conceding goals, as they saw their defence breached 17 times in their last five games.
Greg Vanney’s troops are last in the Western Conference ahead of their encounter with third-placed San Diego FC.
Bearing that in mind, San Diego are the expected winners at 11/20 (1.55). Teams with these odds usually have a 64.5% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our San Diego vs LA Galaxy predictions.
We have also pointed out that four of Galaxy's last five games went above the 3.5-goal mark. For this reason, over 3.5 total goals has an appealing look at 7/5 (2.40). That one has a 41.7% chance of landing.
Most recent H2Hs: Galaxy to avoid the sweep?
It is important to note that this is San Diego's first season in the MLS, and these teams have only ever met once, when San Diego defeated Galaxy in the reverse fixture, 2-0.
USA MLS 24/02/25
LA Galaxy
San Diego FC
San Diego preview: Looking to extend their unbeaten run
Coach Varas could still be without injured Danish forward Marcus Ingvartsen for this contest, while defenders Hamady Diop and Andres Reyes are expected to be back after injury layoffs.
Predicted lineup: Santos (GK), Verhoeven, McVey, McNair, Bombino, Godoy, Tverskov, Torre, Mighten, Dreyer & Lozano.
USA MLS 18/05/25
D
Sporting Kansas City
0
San Diego FC
0
USA MLS 15/05/25
W
Colorado Rapids
0
San Diego FC
2
USA MLS 11/05/25
W
St. Louis City SC
1
San Diego FC
2
USA MLS 04/05/25
W
FC Dallas
0
San Diego FC
5
USA MLS 26/04/25
L
Real Salt Lake
3
San Diego FC
1
Los Angeles Galaxy preview: Eyeing their first win of the season
Former Barcelona man Riqui Puig remains sidelined with a cruciate ligament injury, while Joseph Paintsil has regained match fitness and will likely start.
Predicted lineup: McCarthy (GK), Yamane, Garces, Yoshida, Nelson, Cerrillo, Sanabria, Pec, Reus, Fagundez & Paintsil.
USA MLS 10/05/25
L
New York Red Bulls
7
LA Galaxy
0
USA MLS 04/05/25
L
Sporting Kansas City
1
LA Galaxy
0
USA MLS 28/04/25
L
Portland Timbers
4
LA Galaxy
2
USA MLS 19/04/25
L
Austin FC
1
LA Galaxy
0
USA MLS 13/04/25
D
Houston Dynamo
1
LA Galaxy
1
Player to watch: Anders Dreyer

Anders Dreyer has been impressive since he joined San Diego FC from Anderlecht in January. In 15 appearances across all competitions, the Danish forward has registered eight goals and five assists.
Moreover, Dreyer scored a brace in the reverse fixture and will fancy his chances against LA Galaxy once again.