In the UEFA Europa League fifth-round games, Italian giants Roma welcome Danish side Midtjylland to the Stadio Olimpico on Thursday evening, aiming to build on their recent win in the competition.
Entering this fixture, the home team are in excellent form, boasting a record of four wins and just one loss. They are also currently on a three-game winning streak, which includes their most recent 3-1 victory against Cremonese last weekend. They also secured a crucial 2-0 away win against Rangers in Europe.
The visitors, meanwhile, travel to Rome in good form, sitting top of the Europa League standings with a flawless record and securing a dominant 3-1 win over Celtic in their previous European game. However, in their recent league outing, they suffered a 2-1 away defeat to Sonderjyske, ending their unbeaten streak in their last five games.
Read our Roma vs Midtjylland predictions and preview to find out, but remember to also check our other Europa League predictions.
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Roma vs Midtjylland prediction: The Giallorossi to win
Key statistics
- The Giallorossi have secured a first-half win in three of their last five games.
- Roma have won back-to-back home games in the Serie A.
- The home team have won by a 2-0 scoreline in their last two games.
Correct score prediction: Roma 2-0 Midtjylland
We expect a tight encounter at the Stadio Olimpico, given the form the two teams are currently having, but we are backing the home side to edge it.
Roma have been formidable at home recently and will want to use their home advantage in their favour, while Midtjylland have been the surprise package of the tournament so far, winning all their games and will be a big threat to the host.
However, we believe Roma's individual quality and home advantage will prove the difference, and we are predicting the Giallorossi will end the Wolves’ European unbeaten run by securing a 2-0 victory.
Pre-match odds and win probability: Roma are clear favourites
- Home: 4/9 (1.44) – 69.2%
- Draw: 18/5 (4.60) – 21.7%
- Away: 5/1 (6.00) – 16.7%
*Odds provided by Ladbrokes. Subject to change.*
Based on the odds given, Roma are clear favourites to win the game, with odds of 1.44, giving them a 69.2% implied chance of victory. Midtjylland are priced at 6.00 (16.7%), making them underdogs, while the draw at 4.60 (21.7%) suggests Roma are widely expected to control the game and secure all three points.
Most recent head-to-head: No previous history
These two sides have never met in a European game, meaning there is no official head-to-head record for this clash. However, despite this, Roma's vast experience in European competitions compared to their Danish counterparts gives them an edge. Both teams will be eager to get the first win in their first-ever encounter.
After reviewing our key Roma vs Midtjylland predictions, be sure to visit our website for the remaining football betting tips today.
Roma preview: Some injury concerns
Roma have several injury concerns ahead of this clash. Edoardo Bove is sidelined due to heart problems, while Angelino is currently out with a virus.
Mario Hermoso and Leon Bailey are both dealing with muscle injuries and will remain unavailable for the time being. Paulo Dybala is also ruled out as he continues his recovery from a thigh injury. Artem Dovbyk remains sidelined with a hip injury and is not expected to return just yet.
Predicted lineup: Svilar (GK), Mancini, N'Dicka, Ziolkowski, Celik, Cristante, Kone, Wesley, Soule, Pellegrini & Baldanzi
Last five fixtures
- 23.11.25 – Cremonese 1–3 AS Roma
- 09.11.25 – AS Roma 2–0 Udinese
- 06.11.25 – Rangers 0–2 AS Roma
- 02.11.25 – AC Milan 1–0 AS Roma
- 29.10.25 – AS Roma 2–1 Parma
Midtjylland preview: Some key players out of the clash
Heading into the game, Midtjylland have some injury worries, with Ovie Ejeheri currently injured and doubtful to feature. Adam Gabriel is sidelined with a foot injury and will not be available for the time being. Edward Chilufya is also ruled out as he continues recovering from a knee issue.
Predicted lineup: Olafsson (GK), Mbabu, Lee, Bech, Erlic, Billing, Castillo, Simsir, Cho, Franculino Dju & Osorio
Last five fixtures
- 23.11.25 – Sonderjyske 2–1 Midtjylland
- 09.11.25 – Randers FC 0–2 Midtjylland
- 06.11.25 – Midtjylland 3–1 Celtic
- 03.11.25 – Midtjylland 1–1 Aarhus
- 30.10.25 – Midtjylland 4–0 Silkeborg
Player to watch: Dju Franculino
Midtjylland star Dju Franculino is a huge threat that Roma need to be wary of in this game. The forward is in the form of his life and he is currently the top scorer in the Europa League.
The striker has three goals and one assist to his name in the competition and he has scored in eight consecutive games and has a total of 14 goals and three assists in all competitions this season. His presence will be a big issue for the Giallorossi and they will need to find a way to stop him.