Lyon women will take on Roma women on Wednesday, 20 November in a huge match at the top of Group A in the Women's Champions League.
The hosts are currently in first position in the group after winning all three of their opening matches but Roma have the chance to close the current three-point gap this week should they pick up the win in France.
As part of our latest round of Women's Champions League betting tips, here is our Lyon vs Roma Women prediction.
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Lyon vs RomaWomen prediction: A comfortable night ahead for the hosts
Key Stats
- Lyon are unbeaten in all competitions this season (ten wins, one draw).
- Roma have already tasted defeat twice this season.
- Lyon are yet to concede a goal in Group A of the Champions League.
- Lyon have kept a clean sheet in each of their last ten matches in all competitions.
Correct score prediction: Lyon 3-0 Roma
Winning to nil has become a habit for Lyon this season and it's difficult to imagine Roma bucking that trend considering they failed to score on home soil against them last weekend. The French side have been rampant recently and have scored 22 goals in their last three outings so backing them to just score three on Wednesday is perhaps a little harsh.
Pre-game odds and win probability: Chelsea are the huge favourites
- HOME: 1/9 (1.11) – 90%
- DRAW: 7/1 (8.00) – 12.5%
- AWAY: 16/1 (17.00) – 5.9%
*odds from Ladbrokes, subject to change
The Lyon vs Roma women odds back up our theory that this should be a routine night for the hosts as they look to secure top spot in Group A. Ladbrokes have given Lyon women a 90% chance of getting the job done on the night while Roma women have been given just a 5.9% chance of coming away with the three points.
Check out our betting tips today page for more Women's Champions League predictions this week.
Most recent H2Hs: A second-ever meeting
This will only be the second time that Lyon women and Roma women have gone head to head with each other with the only previous meeting coming last week in Italy. After running out as 2-0 winners in Rome, Lyon will be confident of going 2/2 against the Italian giants.
UEFA Women's Champions League 13/11/24
Roma Women
Lyon Women
Lyon women preview: The perfect team?
There is a reason why Lyon women have been so dominant in Europe over the past decade, competing in six of the last nine Champions League finals. They have a team that can score goals in abundance, as proven by their 11-0 win over St Ettiene at the weekend, as well as keep things rock solid at the back, as proven by their ten consecutive clean sheets.
Predicted lineup: Endler (GK), Carpenter, Gilles, Renard, Svava, Egurrola, Marozsan, Horan, Diani, Chawinga, Dumornay
UEFA Women's Champions League 27/04/25
L
Arsenal Women
4
Lyon Women
1
France Division 1 Women 23/04/25
W
Nantes Women
0
Lyon Women
2
UEFA Women's Champions League 19/04/25
W
Arsenal Women
1
Lyon Women
2
France Division 1 Women 12/04/25
D
Paris FC Women
2
Lyon Women
2
France Division 1 Women 30/03/25
W
FC Fleury 91 Women
0
Lyon Women
4
Roma women preview: A case of damage limitation?
Roma barely managed to lay a glove on Lyon last week when the two sides met in Italy so they won't be overly confident ahead of this one. If they can keep the scoreline respectable and take some positives from the match, then they will be pleased.
Predicted lineup: Ceasar (GK), Thogersen, Cissoko, Minami, Di Guglielmo, Kumagai, Greggi, Giugliano, Haavi, Glionna, Giacinti
UEFA Women's Champions League 17/12/24
W
Galatasaray Women
0
Roma Women
3
Italy Serie A Women 14/12/24
W
Napoli Women
1
Roma Women
2
UEFA Women's Champions League 11/12/24
L
Wolfsburg Women
6
Roma Women
1
Italy Serie A Women 06/12/24
W
Como Women
1
Roma Women
2
Italy Serie A Women 24/11/24
D
Sassuolo Women
1
Roma Women
1
Player to watch: Lindsey Horan

Lindsey Horan is excelling for Lyon once again this season and is showing why she is considered as one of the best goalscoring midfielders in the world. The USA international has scored nine goals in just six league appearances so far this season and will now be looking to make her mark in the Women's Champions League.