The Stadio Olimpico in Rome will host one of the biggest Serie A clashes of the weekend on Saturday as Roma take on Inter Milan after the 2026 FIFA World Cup qualifiers.
The Giallorossi are currently second on the league table, with four wins in their last five games. They returned to winning ways following a 2-1 away victory against Fiorentina.
The Nerazzurri have also found their groove after an initial stumble, winning their last five games across all competitions. Their last league outing saw them secure a 4-1 home win against Cremonese and they are currently fourth on the table. They recently played a club friendly against Atletico Madrid, during the international break, where they lost 2-1 on penalties.
Read our Roma vs Inter Milan predictions and preview to find out, but remember to also check our other Serie A predictions.
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Roma vs Inter Milan prediction: Visitors to run away with narrow win
Key statistics
- Inter Milan have claimed four victories in their last five meetings with Roma.
- Four of their last five games have ended with no BTTS.
- The Nerazzurri have won by a 1-0 scoreline twice in their last five encounters.
Correct score prediction: Roma 0-1 Inter Milan
The Nerazzurri have been in good form in their previous games and we are predicting a narrow 1-0 victory for them in this encounter. Inter Milan have won by this scoreline twice in their last five meetings. We expect a difficult game based on their form this season, but we believe the visitors will edge it out with a narrow win.
Pre-match odds and win probability: Inter slight favourites
- Home: 11/5 (3.20) – 31.3%
- Draw: 11/5 (3.20) – 31.3%
- Away: 5/4 (2.25) – 44.4%
*Odds provided by Ladbrokes. Subject to change.*
With both teams in form this past few games, the match is expected to be a tight game. The Nerazzurri have been given a slight favourable chance with a 44.4% chance of victory at 2.25 odds. Both a Giallorossi win and a draw are priced at 3.20 (31.3%), suggesting a tight encounter where Inter holds a marginal edge heading into the fixture.
Most recent head-to-head: A history of Nerazzurri dominance
Taking a look at their recent meetings, the last five competitive games between the two sides show that Inter Milan have won more games. The visitors have won four compared to Roma’s one, with no draws. In their most recent Serie A meeting in April 2025, Roma claimed a 1-0 victory, showing that the Giallorossi can also win the match, depending on how good the team is in the game.
Italy Serie A 27/04/25
Inter Milan
Roma
Italy Serie A 20/10/24
Roma
Inter Milan
Italy Serie A 10/02/24
Roma
Inter Milan
Italy Serie A 29/10/23
Inter Milan
Roma
Italy Serie A 06/05/23
Roma
Inter Milan
After reviewing our key Roma vs Inter Milan predictions, be sure to visit our website for the remaining football betting tips today.
Roma preview: Just two players out of the clash
Roma manager Gian Piero Gasperini will be without Edoardo Bove due to heart problems, with no confirmed return date at this stage. Angelino is also ruled out as he recovers from a virus, and he is expected to return in November.
Predicted lineup: Svilar (GK), Celik, Mancini, Ndicka, Wesley, Cristante, Kone, Tsimikas, Soule, Pellegrini & Dovbyk
Last five fixtures
- 05.10.25 – Fiorentina 1 – 2 AS Roma
- 02.10.25 – AS Roma 0 – 1 Lille
- 28.09.25 – AS Roma 2 – 0 Verona
- 24.09.25 – Nice 1 – 2 AS Roma
- 21.09.25 – Lazio 0 – 1 AS Roma
Inter Milan preview: Multiple injury trouble
Cristian Chivu’s team will miss Marcus Thuram, who is sidelined with a thigh injury. Matteo Darmian is also unavailable due to a muscle injury, with a projected return in November.
Meanwhile, Raffaele Di Gennaro remains out after suffering a broken hand and he is not expected to be back until November.
Predicted lineup: Sommer (GK), Akanji, Acerbi, Bastoni, Dumfries, Barella, Calhanoglu, Mkhitaryan, Dimarco, Bonny, Martinez
Last five fixtures
- 10.10.25 – Atl. Madrid 2 – 1 Inter (friendly, lost on penalties 1-1 AET)
- 04.10.25 – Inter 4 – 1 Cremonese
- 30.09.25 – Inter 3 – 0 Slavia Prague
- 27.09.25 – Cagliari 0 – 2 Inter
- 21.09.25 – Inter 2 – 1 Sassuolo
Player to watch: Lautaro Martinez
One player who will cause a problem for Roma is Lautaro Martinez. He has scored six goals and provided one assist in all competitions this season. His presence in the team has made Inter Milan a formidable attacking side. He will be a huge threat in the box and Roma will need to be watchful and avoid him getting on the end of any ball in their box.