Real Madrid are targeting the win that would effectively guarantee their progress into the knockout phase play-offs on Wednesday. Our Real Madrid vs RB Salzburg prediction and Champions League betting tips consider whether Los Blancos can see off their Austrian opponents.
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Real Madrid vs RB Salzburg prediction: Vinicius to strike last in big home win
Key stats
- Our Real Madrid vs RB Salzburg betting tips take into account that Los Blancos have won seven of their last eight games, scoring 28 times in the process.
- RB Salzburg have lost four of their last eight matches in all competitions.
- They’ve averaged 3.00 goals per game conceded in the league phase of the Champions League, losing all but one of their matches.
Correct score prediction: Real Madrid 5-1 RB Salzburg
Even in their own league, where they are only in fifth place, RB Salzburg are having a miserable season.
They’ve a new manager at the helm who takes charge of his first competitive game here as Salzburg return from their winter break, but judging by a 6-0 friendly defeat to Bayern Munich earlier this month, they’ll struggle to compete with the holders. A big home win looks likely.
Pre-game odds and win probability: Los Blancos the huge favourites
- HOME: 1/12 (1.08) – 92.3%
- DRAW: 11/1 (12.00) – 8.3%
- AWAY: 22/1 (23.00) – 4.3%
*odds from Ladbrokes, subject to change
The hosts are the favourites according to the Real Madrid vs RB Salzburg odds with an implied probability of 92.3% that they win this match.
They head into the game following a 4-1 comeback win against Las Palmas in La Liga, with Kylian Mbappe scoring twice.
As for RB Salzburg, they’ve not played competitively since a 3-0 league win over SK Austria Klagenfurt in December. They lost 3-2 to FC Midtjylland in a friendly last week.
For more from the upcoming action in Europe, today’s football betting tips look at some of the best picks.
Most recent H2Hs: Clubs set for first competitive meeting
Our Real Madrid vs RB Salzburg prediction suggests it’ll be a big win for Carlo Ancelotti’s side in the first ever competitive meeting between the clubs.
Salzburg haven’t won on any of their last seven visits to Spain, with their last win in this country coming by a 1-0 margin against Villarreal in the 2009/10 Europa League.
Elite Club Friendlies 07/08/19

FC Salzburg

Real Madrid
Real Madrid preview: Tchouameni joins injury list
Aurelien Tchouameni has picked up an injury, meaning he joins Eduardo Camavinga, Dani Carvajal and Eder Militao on the sidelines for this one. Lucas Vazquez is suspended.
Predicted Lineup: Courtois (GK), Mendy, Asencio, Rudiger, Valverde, Bellingham, Ceballos, Modric, Vinicius, Mbappe & Rodrygo
Spain La Liga 11/05/25 L Barcelona 4 Real Madrid 3 Spain La Liga 04/05/25 W Celta Vigo 2 Real Madrid 3 Spain Copa del Rey 26/04/25 L Barcelona 3 Real Madrid 2 Spain La Liga 23/04/25 W Getafe 0 Real Madrid 1 Spain La Liga 20/04/25 W Athletic Bilbao 0 Real Madrid 1
RB Salzburg preview: Baptism of fire for Letsch
Thomas Letsch takes charge of Salzburg for the first time in a competitive setting, but he’s missing Maurits Kjaergaard and Karim Konate to injuries.
Predicted Lineup: Blaswich (GK), Terzic, Dedic, Baidoo, Capaldo, Douath, Bidstrup, Diakite, Gloukh, Yeo & Ratkov
Austria Bundesliga 09/05/25 L SK Sturm Graz 4 FC Salzburg 2 Austria Bundesliga 04/05/25 W FK Austria Vienna 0 FC Salzburg 2 Austria Bundesliga 27/04/25 L Wolfsberger AC 2 FC Salzburg 1 Austria Bundesliga 23/04/25 D Wolfsberger AC 1 FC Salzburg 1 Austria Bundesliga 20/04/25 W FK Austria Vienna 1 FC Salzburg 3
Player to watch – Vincius Junior
Given he is currently serving a domestic ban, Vinicius Junior should be fresh and hungry on Wednesday night. The Brazilian has scored five in five Champions League games this term.

Vinicius scoring late
A huge 87% of the goals scored by Vinicius this season in all competitions have come after the break. He has scored after the 76th minute on four occasions.