There’s a big game in the race for Champions League places in La Liga this weekend. Our Real Betis vs Villarreal prediction and La Liga betting tips consider whether either side can claim a big win in the race for fifth place which looks set to be enough for a place in next season’s elite European competition.
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Real Betis vs Villarreal prediction: Ayoze to haunt his old club in draw
Key stats
- Our Real Betis vs Villarreal betting tips take into account that five of the home team’s last six matches in La Liga have seen both teams score.
- 67% of league matches at the Benito Villamarin this term have seen both teams score.
- Villarreal have conceded in 93% of their away games in the Spanish top flight this season.
Correct score prediction: Real Betis 2-2 Villarreal
Betis have been absolutely flying, but they’re at a slight disadvantage here given they were involved in a European quarter-final on Thursday night on this ground.
With Villarreal boasting such a strong away record, Marcelino’s side look capable of getting a good point in what should be a relatively open game between two teams blessed with some skillful attacking talents.
Pre-game odds and win probability: Bookies favour the hosts
- HOME: 13/10 (2.30) – 43.5%
- DRAW: 5/2 (3.50) – 28.6%
- AWAY: 19/10 (2.90) – 34.5%
*odds from Ladbrokes, subject to change
The hosts are the favourites according to the Real Betis vs Villarreal odds, with an implied probability of 43.5% that they win this match.
They head into this game following a comfortable 2-0 win over Jagiellonia Białystok in the Conference League, extending a fine run of results in all competitions for the Seville club.
As for Villarreal, they were involved in a big top-five showdown last weekend, drawing 0-0 at home to Athletic Club, with Pape Gueye becoming the fastest ever player to five red cards in La Liga following his sending off in that match.
For more from the upcoming matches in Europe, today’s free football tips look at some of the best picks.
Most recent H2Hs: Both teams normally score
Our Real Betis vs Villarreal prediction suggests we’ll see both teams get on the scoresheet for the fifth meeting in a row on Sunday.
Villarreal have a decent record at the Benito Villamarin, losing on only one of their last five visits.
Spain La Liga 15/12/24

Villarreal

Real Betis
Spain La Liga 10/03/24

Real Betis

Villarreal
Spain La Liga 13/08/23

Villarreal

Real Betis
Spain La Liga 12/03/23

Villarreal

Real Betis
Spain La Liga 11/09/22

Real Betis

Villarreal
Real Betis preview: Isco not fully fit
Key man Isco is still expected to start the game, although Pellegrini withdrew him at the interval on Thursday due to fitness concerns. We may see light changes from that match, with Abde Ez the only injury concern for the hosts.
Predicted Lineup: Adrian (GK), Perraud, Bartra, Llorente, Ruibal, Altimira, Cardoso, Lo Celso, Isco, Antony & C. Hernandez
Spain La Liga 13/04/25 L Villarreal 2 Real Betis 1 UEFA Conference League 10/04/25 W Jagiellonia Bialystok 0 Real Betis 2 Spain La Liga 05/04/25 D Barcelona 1 Real Betis 1 Spain La Liga 30/03/25 W Sevilla 1 Real Betis 2 Spain La Liga 16/03/25 W Leganes 2 Real Betis 3
Villarreal preview: Gueye serves ban
The visitors are missing the suspended Gueye, while Raul Albiol and Ilias Akhomach are out injured. Tajon Buchanan is rated doubtful.
Predicted Lineup: Junior (GK), Cardona, Costa, Foyth, Femenia, Baena, Parejo, Comesana, Pino, Ayoze & Barry
Spain La Liga 13/04/25 W Real Betis 1 Villarreal 2 Spain La Liga 06/04/25 D Athletic Bilbao 0 Villarreal 0 Spain La Liga 30/03/25 W Getafe 1 Villarreal 2 Spain La Liga 15/03/25 L Real Madrid 2 Villarreal 1 Spain La Liga 08/03/25 L CD Alaves 1 Villarreal 0
Player to watch – Ayoze Perez
Villarreal signed Ayoze Perez from Real Betis last summer, and the 31-year-old won’t be expecting a warm reception here. He could have a big impact on the game though, with a healthy return of 12 goals from 22 appearances in La Liga for his new club so far.

Ayoze having more shots for the Yellow Submarine
The Spain international has posed a bigger goal threat since making the switch. He’s averaging 2.6 shots per game in La Liga this term, compared to 2.2 in his final season at Betis.