The UEFA Conference League final takes place in Wroclaw on Wednesday night. Our Real Betis vs Chelsea prediction and Conference League betting tips consider whether the Spanish side can upset Enzo Maresca’s men.
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Real Betis vs Chelsea prediction: Isco to shine in score draw
Key stats
- Our Real Betis vs Chelsea betting tips take into account that the Seville-based side have only failed to score in two of their 16 Conference League fixtures this term.
- Chelsea average 2.93 goals scored per game in this competition this season.
- Five of their last eight matches in the Conference League have seen both teams score.
Correct score prediction: Real Betis 2-2 Chelsea
Chelsea have been the clear favourites to win this competition all season, and it’s no surprise that they’ve reached the final, particularly given their favourable path through the last few rounds.
They will face a real test here though, with Real Betis very impressive in the second half of the season in both domestic and European competition. With Isco and Antony linking up brilliantly, they look capable of pushing the Blues all the way.
Pre-game odds and win probability: Chelsea the odds-on favourites
- REAL BETIS: 16/5 (4.20) – 23.8%
- DRAW: 5/2 (3.50) – 28.6%
- CHELSEA: 5/6 (1.83) – 54.5%
*odds from Ladbrokes, subject to change
The Premier League side are the favourites according to the Real Betis vs Chelsea odds, with an implied probability of 54.5% that they win this match in regulation time.
They head into the game following a vital 1-0 win at Nottingham Forest on Sunday which clinched Champions League qualification.
That match saw them round off their Premier League season with the youngest-ever average age of any club in a single campaign in the competition, at 24 years and 36 days. Winning a trophy would be another huge boost to a youthful squad that has been heavily criticised at times.
As for Real Betis, they signed off for the season in La Liga with a 1-1 draw against Valencia on Friday, in what was a largely meaningless game.
For more from the upcoming matches in Europe, today’s free football betting tips look at some of the best picks.
Most recent H2Hs: First meeting in 20 years
Our Real Betis vs Chelsea prediction suggests we’ll get a competitive clash in the first meeting between the clubs since two Champions League group-stage fixtures in 2005.
Both of those games ended in home wins, while Chelsea defeated Betis 5-2 on aggregate in the 1997/98 UEFA Cup Winners' Cup at the quarter-final stage.
Real Betis preview: Pellegrini missing at least four
Manuel Pellegrini is missing Hector Bellerin, Diego Llorente, Chimy Avila and Marc Roca to injuries. He has an additional doubt over Giovani Lo Celso, but Fran Vietes, his regular keeper in this competition, is fit again and is hoping to get the nod in goal ahead of Adrian.
Predicted Lineup: Vietes (GK), Sabaly, Bartra, Natan, Rodriguez, Cardoso, Fornals, Antony, Isco, Ez & Bakambu
Spain La Liga 11/05/25
D Osasuna 1 Real Betis 1 UEFA Conference League 08/05/25
D Fiorentina 2 Real Betis 2 Spain La Liga 04/05/25
W Espanyol 1 Real Betis 2 UEFA Conference League 01/05/25
W Fiorentina 1 Real Betis 2 Spain La Liga 24/04/25
W Valladolid 1 Real Betis 5
Chelsea preview: Fofana sidelined
There’s no Wesley Fofana for Chelsea due to injury. They also have doubts over Marc Guiu and Christopher Nkunku. Conference League regulars Kiernan Dewsbury-Hall and Filip Jorgensen may come into the side, with a few changes likely from the trip to Nottingham.
Predicted Lineup: Jorgensen (GK), James, Adarabioyo, Badiashile, Cucurella, Caicedo, Dewsbury-Hall, Madueke, Palmer, Sancho & Jackson
England Premier League 11/05/25
L Newcastle 2 Chelsea 0 UEFA Conference League 08/05/25
W Djurgarden 0 Chelsea 1 England Premier League 04/05/25
W Liverpool 1 Chelsea 3 UEFA Conference League 01/05/25
W Djurgarden 1 Chelsea 4 England Premier League 26/04/25
W Everton 0 Chelsea 1
Player to watch – Isco
Isco is playing some of the best football of his career at the age of 33. Despite missing nearly half of the season due to injury, the Spaniard registered nine goals and eight assists in 22 appearances in La Liga 2024/25.
Isco striking late in Europe
The playmaker has also chipped in with two goals in the Conference League. Both came in the 75th minute or later against Vitoria Guimaraes.