Liverpool will be looking to extend their 100% record in this season's Champions League when they make the tricky trip to Germany to face RB Leipzig on Wednesday night.
The hosts have lost both of their games so far but striker Benjamin Sesko has been in good form and should cause the Liverpool defence a few headaches.
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RB Leipzig vs Liverpool prediction: Goals at both ends of the pitch?
Key Stats
- RB Leipzig have only failed to score in one of their last six outings.
- Liverpool have won each of their three competitive and non-competitive previous meetings with RB Leipzig.
- Benjamin Sesko has scored three goals in two Champions League appearances this season.
Correct score prediction: RB Leipzig 1-2 Liverpool
Liverpool have scored at least two goals in five of their last six matches across all competitions and have won their last two Champions League games against RB Leipzig, while the hosts have lost their opening two games in this competition but have scored in five of their last six matches in league and cup.
Pre-game odds and win probability: Liverpool the bookmaker's pick
- HOME: 14/5 (3.80) – 26.3%
- DRAW: 16/5 (4.20) – 23.8%
- AWAY: 10/11 (1.91) – 52.4%
*odds from Ladbrokes, subject to change
Liverpool are the expected winner of this game with a probability of 52.4% but we are expecting a close and competitive 90 minutes between the two sides.
You can find all our predictions for today's games on our football betting tips page.
Most recent H2Hs: Met three times before
Liverpool have won each of their three competitive and non-competitive games against RB Leipzig with the pair meeting twice in the Champions League in 2021 and once for a pre-season friendly in 2022.
Elite Club Friendlies 21/07/22
RB Leipzig
Liverpool
UEFA Champions League 10/03/21
Liverpool
RB Leipzig
UEFA Champions League 16/02/21
RB Leipzig
Liverpool
RB Leipzig preview: Lost opening two Champions League games
RB Leipzig might sit joint-top of the Bundesliga table after seven games but they are yet to pick up a point in the Champions League.
Marco Rose's side started out with a tricky trip to Atletico Madrid which ended in a 2-1 defeat and then lost at home 3-2 against Juventus.
Amadou Haidara and Lois Openda should be back in contention for the home side but Nicolas Seiwald, David Raum, Assan Ouédraogo and Xaver Schlager will miss the Liverpool game through injury.
Predicted lineup: Gulacsi (GK), Orban, Klostermann, Geertruida, Lukeba, Haidara, Simons, Nusa, Vermeeren, Openda & Sesko
Germany Bundesliga I 10/05/25
D
Werder Bremen
0
RB Leipzig
0
Germany Bundesliga I 03/05/25
D
Bayern Munich
3
RB Leipzig
3
Germany Bundesliga I 26/04/25
L
Eintracht Frankfurt
4
RB Leipzig
0
Germany Bundesliga I 19/04/25
D
Holstein Kiel
1
RB Leipzig
1
Germany Bundesliga I 11/04/25
W
Wolfsburg
2
RB Leipzig
3
Liverpool preview: Sit top of the Premier League table
Liverpool moved back to the top of the Premier League table on Sunday thanks to a 2-1 win over Chelsea at Anfield.
Arne Slot's team followed up their 3-1 win against AC Milan with a 2-0 home win over another Italian side in the form of Bologne to maintain their 100% start to this season's Champions League.
Federico Chiesa is a doubt for the trip to Germany but Harvey Elliot and Alisson are unavailable due to injury.
Predicted lineup: Kelleher (GK), van Dijk, Robertson, Alexander-Arnold, Konate, Jones, Szoboszlai, Gravenberch, Salah, Jota & Gakpo
England Premier League 11/05/25
D
Arsenal
2
Liverpool
2
England Premier League 04/05/25
L
Chelsea
3
Liverpool
1
England Premier League 27/04/25
W
Tottenham
1
Liverpool
5
England Premier League 20/04/25
W
Leicester
0
Liverpool
1
England Premier League 13/04/25
W
West Ham
1
Liverpool
2
Player to watch: Benjamin Sesko
Despite backing Liverpool to edge out their hosts, we've highlighted RB Leipzig striker Benjamin Sesko as our player to watch on Wednesday night.

Sesko, who has often been linked to Erling Haaland due to the pair both being strikers with lots of potential who developed at RB Salzburg before making the move to Germany, has scored three goals in Leipzig's opening two Champions League games this season.
Sesko has three goals in the Champions League already
The 21-year-old scored 14 league goals in his debut season with Leipzig and has netted twice in seven starts of the 2024/25 campaign. We're backing Sesko to score against Liverpool this week which will only enhance his growing reputation in England and we expect to see the talented striker ply his trade in the Premier League before long.