Greek giants Olympiacos and Cypriot side Pafos will kick off the UEFA Champions League phase next Wednesday at the Georgios Karaiskakis Stadium in Piraeus, Greece.
The Reds enter this match in good domestic form, having won their first three league games, with the most recent being a 5-0 victory over Panserraikos in the Greek Super League. The Paphosians, on the other hand, failed to build on their previous win, having lost 1-0 at home to Apollon.
Read our Olympiacos vs Pafos predictions and preview to find out, but remember to also check our other UEFA Champions League predictions.
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Olympiacos vs Pafos prediction: The Reds are favourites to win
Key statistics
- Olympiacos have gone into halftime level in each of their last two league matches.
- The Reds have scored over 2.5 goals in three of their last five games at home.
- Olympiacos have won their last five home games in all competitions.
Correct score prediction: Olympiacos 3-0 Pafos
Olympiacos will face Pafos for the first time in a competitive game and we see the home side coming out on top. We are predicting a 3-0 win for Olympiacos.
The Greek giants have huge experience in European competitions and are very reliable when playing at home, which gives them a big advantage.
The Paphosians deserve credit for their determination and strong qualifying run, but facing Olympiacos is a much tougher challenge. The Reds should be able to secure a comfortable victory.
Pre-match odds and win probability: Winning odds given to Olympiacos
- Home: 10/21 (1.48) – 67.7%
- Draw: 10/3 (4.33) – 23.1%
- Away: 11/2 (6.50) – 15.4%
*Odds provided by Ladbrokes. Subject to change.*
The odds clearly show the Red-and-Whites as strong favourites, with a 67.7% chance of winning. This reflects their proven strength at home and their long history in European competitions.
A draw is less likely at 23.1%, suggesting that while the game could be competitive, Olympiacos are still expected to take control.
The Lions, on the other hand, are seen as big underdogs with just a 15.4% chance, meaning it would take a major upset for them to get a result against such an experienced opponent.
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Most recent head-to-head: No record of previous meetings
Olympiacos and Pafos have no recent head-to-head history in competitive matches. This will mark the very first meeting between the two sides in the UEFA Champions League. Despite both teams not meeting each other in the past, we expect Jose Luis Mendilibar’s side to come out of the game with a comfortable win.
After reviewing our key Olympiacos vs Pafos predictions, be sure to visit our website for the remaining football betting tips today.
Olympiacos preview: Full squad available
Mendilibar’s team are going into this match with a healthy squad, with only a few minor injury concerns. However, none of the players are expected to be sidelined for a long period, which means the manager will have a full team to pick from for this match.
Predicted lineup: Tzolakis (GK), Rodinei, Pirola, Ortega, Retsos, Costinha, Chiquinho, Podence, Garcia, Hezze & Martins
Last five fixtures
- 13.09.25 – Olympiacos Piraeus 5 – 0 Panserraikos
- 30.08.25 – Volos 0 – 2 Olympiacos Piraeus
- 23.08.25 – Olympiacos Piraeus 2 – 0 Asteras Tripolis
- 16.08.25 – Inter 2 – 0 Olympiacos Piraeus
- 14.08.25 – Napoli 2 – 1 Olympiacos Piraeus
Pafos preview: Clean bill of health
Juan Carlos Carcedo’s team has a relatively healthy squad heading into this fixture. The team has been performing well recently and has no major injuries to report. The manager will be able to field a full-strength side, which is a significant advantage as they look to cause an upset against a stronger opponent.
Predicted lineup: Michael (GK), Goldar, Luckassen, Pileas, Correia, Sunjic, Dragomir, Pepe, Bruno, Orsic & Anderson
Last five fixtures
- 13.09.25 – Pafos 0 – 1 Apollon
- 31.08.25 – APOEL 0 – 1 Pafos
- 26.08.25 – Pafos 1 – 1 Crvena zvezda
- 19.08.25 – Crvena zvezda 1 – 2 Pafos
- 12.08.25 – Pafos 2 – 0 Dynamo Kyiv
Player to watch: Ayoub El Kaabi
A key player to watch in this match is Ayoub El Kaabi from Olympiacos. The striker has made a strong start to the season, scoring a goal in his first two games.
El Kaabi has a habit of scoring important goals and his presence in the box makes him the main attacking threat for Olympiacos. Pafos’ defence will need to stay organised and disciplined, as any loss of concentration could allow him to make the difference in this game.