The Stadio Diego Armando Maradona in Naples is set for an electrifying top-of-the-table clash on Saturday as Napoli host Inter Milan in the Serie A. Gli Azzurri have been in form since the start of the season, taking their form into the international break. However, following the return of league football, they suffered a disappointing 1-0 away loss to Torino and also lost 6-2 to PSV in their UEFA Champions League games.
On the other hand, the Nerazzurri have also built momentum in recent games and continued their form following a 1-0 victory over AS Roma away from home, backing it up with a 4-0 win over Royale Union SG in the Champions League and making it four wins in their last five games.
Read our Napoli vs Inter predictions and preview to find out, but remember to also check Serie A predictions.
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Napoli vs Inter prediction: Tight encounter expected
Key statistics
- First-half draws have been played in two of their last five encounters.
- Their last three meetings have ended in a 1-1 scoreline.
- BTTS has been played in their last three clashes.
Correct score prediction: Napoli 1-1 Inter
Both teams are in good form this season and are currently the top two teams on the league table. We are predicting a 1-1 draw for this encounter based on their previous meetings. They have played a draw in their last three encounters, with those three games ending in a 1-1 draw. We do not expect anything to change in this encounter and we expect both teams to settle for a draw in this game.
Pre-match odds and win probability: Inter slight favourites
- Home: 2/1 (3.00) – 33.3%
- Draw: 11/5 (3.20) – 31.3%
- Away: 7/5 (2.40) – 41.7%
*Odds provided by Ladbrokes. Subject to change.*
The Nerazzurri will face a difficult task against Napoli, but are slight favourites with a 41.7% chance of victory at 2.40 odds. Napoli, priced at 3.00, have a 33.3% chance to win, while a draw at 3.20 (31.3%) remains a strong possibility. The odds show a tight encounter between the two Serie A heavyweights at the Stadio Diego Armando Maradona.
Most recent head-to-head: A tight battle between both teams
Looking at their last five meetings, Napoli and Inter Milan have had a very tight encounter. The Nerazzurri have secured two wins, while Gli Azzurri have no wins, with the remaining three games ending in draws. Their most recent Serie A meeting was a 1 – 1 draw in March 2025, which shows that this fixture has been very competitive.
Italy Serie A 01/03/25
Napoli
Inter Milan
Italy Serie A 10/11/24
Inter Milan
Napoli
Italy Serie A 17/03/24
Inter Milan
Napoli
Italy Super Cup 22/01/24
Napoli
Inter Milan
Italy Serie A 03/12/23
Napoli
Inter Milan
After reviewing our key Napoli vs Inter predictions, be sure to visit our website for the remaining football betting tips today.
Napoli preview: Key players injured
Antonio Conte will be looking to get his team back to winning ways, but will have to do it with several injury concerns ahead of their upcoming clash. Nikita Contini is doubtful with a broken hand, while Amir Rrahmani, Stanislav Lobotka, and Romelu Lukaku are all sidelined with thigh or hamstring injuries, each expected to return in November. Rasmus Hojlund is also a doubt due to a muscle problem and will be assessed closer to kickoff.
Predicted lineup: Milinkovic-Savic (GK), Di Lorenzo, Beukema, Buongiorno, Spinazzola, Gilmour, Politano, Anguissa, De Bruyne, McTominay & Lucca
Last five fixtures
- 21.10.25 – PSV 6 – 2 Napoli
- 18.10.25 – Torino 1 – 0 Napoli
- 05.10.25 – Napoli 2 – 1 Genoa
- 01.10.25 – Napoli 2 – 1 Sporting CP
- 28.09.25 – AC Milan 2 – 1 Napoli
Inter preview: Visitors struggling with injuries
Cristian Chivu’s team will be without Marcus Thuram, who is sidelined with a thigh injury and is expected to return in November. Raffaele Di Gennaro is also unavailable due to a broken hand, with his comeback projected for November. Meanwhile, Matteo Darmian is recovering from a muscle injury and is anticipated to be back in November.
Predicted lineup: Sommer (GK), Bisseck, de Vrij, Bastoni, Dumfries, Frattesi, Calhanoglu, Zielinski, Augusto, Esposito & Martinez
Last five fixtures
- 21.10.25 – Royale Union SG 0 – 4 Inter
- 18.10.25 – AS Roma 0 – 1 Inter
- 10.10.25 – Atl. Madrid 2 – 1 Inter
- 04.10.25 – Inter 4 – 1 Cremonese
- 30.09.25 – Inter 3 – 0 Slavia Prague
Player to watch: Scott McTominay

An important player to watch in this clash is Scott McTominay, Napoli’s star. The midfielder has made a strong impact this season, scoring three goals in all competitions in his last three games. With Napoli set to take on Inter Milan, McTominay will be aiming to build on his impressive form and help his team in the game.