Monaco vs Tottenham prediction, odds & betting tips 22/10/2025
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Monaco or draw

Monaco have avoided defeat in four of their last five matches.

Monaco will take on Tottenham in the UEFA Champions League on Wednesday, 22 October, in a match that feels particularly significant for the hosts.

Monaco are yet to win a game in the Champions League this season, and another defeat on Wednesday would leave them with a mountain to climb in terms of qualification for the knockout stages.

For Tottenham, a win would take them to a healthy tally of seven points from three matches played in this season's league phase.

As part of this week's round of Champions League betting tips, check out our Monaco vs Tottenham prediction below.

Monaco vs Tottenham prediction: The hosts to take something from the match

Key Stats

  • Tottenham have won just one of their last four matches in all competitions.
  • Monaco have drawn their last three matches in all competitions.
  • More than three goals have been scored in three of the four matches that these two teams have played in the Champions League this season.

Correct score prediction: Monaco 2-2 Tottenham

Monaco dug out a 2-2 draw with Man City last time out in the Champions League, so repeating that feat against a lesser English side in Tottenham is definitely possible.

Pre-game odds and win probability: Not much to split the two teams

  • HOME: 15/8 (2.88) – 34.8%
  • DRAW: 13/5 (3.60) – 27.8%
  • AWAY: 13/10 (2.30) – 43.5%

*odds from Ladbrokes, subject to change

The Monaco vs Tottenham odds suggest that we are in for a tight affair on Tuesday night. Ladbrokes have made Tottenham the narrow favourites, giving them a 43.5% chance of winning the match, while Monaco have been given a 34.8% chance of picking up their first win of the Champions League campaign.

You can find all our predictions for today's games on our football betting tips page.

Most recent H2Hs: A first meeting in nine years

This will be the first time that these two teams have faced each other since the group stages of the 2016/17 Champions League. During that campaign, Monaco won 2-1 at White Hart Lane before winning again in France towards the end of the group stages.

Monaco preview: Dier misses out

Eric Dier won't have the opportunity to face his former club this week as he has been ruled out with a hamstring problem. The central defender joins Lukas Hradecky, Vanderson, Denis Zakaria, Christian Mawissa and Lamine Camara in the treatment room. Paul Pogba still isn't considered match fit.

Predicted lineup: Kohn (GK), Salisu, Kehrer, Henrique, Diatta, Coulibaly, Teze, Ouattara, Akliouche, Fati, Balogun

Last five results

  • Angers 1-1 Monaco
  • Monaco 2-2 Nice
  • Monaco 2-2 Man City
  • Lorient 3-1 Monaco
  • Monaco 5-2 Metz

Tottenham preview: Problems at the back

Tottenham are coming into this one with a bit of a defensive injury crisis after Destiny Udogie and Cristian Romero both picked up injuries in the build-up to the match against Aston Villa at the weekend. Mick van de Ven is available, but a booking would see him miss Spurs' next European fixture.

Predicted lineup: Vicario (GK), Porro, Danso, Van de Ven, Spence, Sarr, Bentancur, Bergvall, Johnson, Richarlison, Simons

Last five results

  • Tottenham 1-2 Aston Villa
  • Leeds 1-2 Tottenham
  • Bodo/Glimt 2-2 Tottenham
  • Tottenham 1-1 Wolves
  • Tottenham 3-0 Doncaster

Player to watch: Folarin Balogun

Folarin Balogun
Folarin Balogun – Photo by IMAGO/Psnewz

Folarin Balogun is still yet to hit his true potential, but he will be a player that Tottenham will be wary of on Wednesday night, not least because of his ties to Arsenal. Balogun would love nothing more than to find the back of the net this week, and get his season up and running.


Andy is a freelance Sports Journalist with ten years of experience covering football in the United Kingdom and abroad for various publications including the Manchester Evening News, UtdReport and Football Whispers. Andy also has a keen interest in basketball, cricket, golf and tennis and has covered major sporting events such as the Masters in Augusta.