Manchester United kick-off their Europa League campaign at home to Dutch side Twente where Erik ten Hag will be expected to get off to a winning start.
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Man Utd vs Twente prediction: Home win and a clean sheet?
Key Stats
- Man Utd have won three of their last six matches in all competitions.
- Over 2.5 goals have been scored in four of the hosts' last five outings.
- At least three goals have been produced in three of Twente's last six fixtures.
Correct score prediction: Man Utd 3-0 Twente
Man Utd haven't conceded a single goal in any of their last three fixtures and have scored ten goals during that period, so you can see why we have backed a correct score prediction of 3-0 in the home side's favour.
Pre-game odds and win probability: Odds stacked against the visitors
- HOME: 4/13 (1.31) – 76.5%
- DRAW: 51/10 (6.10) – 16.4%
- AWAY: 9/1 (10.00) – 10%
*odds from Ladbrokes, subject to change
Man Utd are the expected winner of this game with a probability of 76.5% and we tend to agree with the bookmakers on this prediction.
You can find all our predictions for today's games on our football betting tips page.
Most recent H2Hs: First encounter
Man Utd lock horns with Dutch side Twente for the very first time in their history on Wednesday night where the Premier League side will be expected to secure all three points.
Man Utd preview: Improving after a slow start
Man Utd fans will certainly be pleased with their team's recent performances following defeats to Brighton and Liverpool.
Erik ten Hag's side won 3-0 at Southampton in the league before thrashing Barnsley 7/10 in the League Cup and while a goalless draw at Crystal Palace isn't great, it did produce yet another clean sheet for the Red Devils.
Luke Shaw, Victor Lindelof, Leny Yoro and Tyrell Malacia won't be available for selection for the Twente game due to injury.
Predicted lineup: Onana (GK), Mazraoui, de Ligt, Dalot, Martínez, Ugarte, Fernandes, Mainoo, Hojlund, Rashford & Diallo
England Premier League 11/05/25
L
West Ham
2
Man Utd
0
UEFA Europa League 08/05/25
W
Athletic Bilbao
1
Man Utd
4
England Premier League 04/05/25
L
Brentford
4
Man Utd
3
UEFA Europa League 01/05/25
W
Athletic Bilbao
0
Man Utd
3
England Premier League 27/04/25
D
Bournemouth
1
Man Utd
1
Twente preview: Sit fourth in the Eredivisie
Old Trafford's Dutch guests have only lost one of their last six matches across all competitions but haven't come up against an opponent as tough as Man Utd so far this season.
Twente were in great form at the weekend as they beat Almere City 5-0 away, making it three games unbeaten in the Eredivisie.
Midfielders Younes Taha and Michal Sadílek look set to miss the trip to England on Wednesday night through injury.
Predicted lineup: Unnerstall (GK), Salah-Eddine, van Rooij, Hilgers, Eiting, Steijn, Bruns, Regeer, Lammers, van Bergen & Rots
Netherlands Eredivisie 11/05/25
W
FC Utrecht
0
FC Twente
2
Netherlands Eredivisie 04/05/25
W
Sparta Rotterdam
0
FC Twente
2
Netherlands Eredivisie 24/04/25
L
PSV
3
FC Twente
1
Netherlands Eredivisie 13/04/25
D
PEC Zwolle
1
FC Twente
1
Netherlands Eredivisie 05/04/25
D
Fortuna Sittard
1
FC Twente
1
Player to watch: Marcus Rashford
Following a difficult season, Marcus Rashford has made a positive start to the 2024/25 campaign with Manchester United.

The England forward has scored three goals in seven appearances across all competitions so far, which is impressive considering he only managed eight in 43 games last season.
Will Marcus Rashford start against Twente?
Rashford didn't start the 0-0 draw with Crystal Palace but were expecting the 26-year-old to get the nod against Twente on Wednesday and wouldn't be surprised to see him add to his goal tally.