The UEFA Conference League group stage continues this Thursday, with German side Mainz 05 hosting Italian opponents Fiorentina at the MEWA ARENA.
Die Nullfunfer come into this fixture with poor domestic form but recent success in Europe. Their last outing saw them avoid a defeat after back-to-back losses, with a 1-1 draw against Werder Bremen in the Bundesliga.
Despite struggling in their domestic campaign, they have had a good start in the European competition this season, winning their first two games and securing a 1-0 victory over Zrinjski last time out.
La Viola have faced a challenging run of results in Serie A and are still without a win in the league this season. They have suffered two defeats in a row, with a 1-0 loss to Lecce last weekend being the latest defeat.
However, despite these domestic struggles, Fiorentina secured a confidence-boosting 3-0 victory over Rapid Wien in their last Conference League match and have maintained a good start in the competition.
Read our Mainz 05 vs Fiorentina predictions and preview to find out, but remember to also check our other UEFA Conference League predictions.
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Mainz 05 vs Fiorentina prediction: Expect a full-time draw
Key statistics
- Both teams have scored at least one goal in three of their last five games.
- Their last meeting ended in a full-time draw.
- Both teams played a first-half draw in their last meeting.
Correct score prediction: Mainz 05 1-1 Fiorentina
Considering Fiorentina and Mainz's strong performance in Europe thus far, we believe the game will end in a tie. Mainz 05 will undoubtedly provide a challenge, benefiting from their home support at the MEWA ARENA, but we predict a final 1-1 scoreline.
However, with their domestic league form, both teams might not be able to find a way around each other in this game, which could end in a draw.
Pre-match odds and win probability: Mainz narrowly favoured
- Home: 13/10 (2.30) – 43.5%
- Draw: 12/5 (3.40) – 29.4%
- Away: 2/1 (3.00) – 33.3%
*Odds provided by Ladbrokes. Subject to change.*
Ahead of this clash, Mainz are seen as the slight favourites at 2.30 odds, giving them a 43.5% chance of victory. The draw is priced at 3.40, reflecting a 29.4% probability.
Fiorentina, on the other hand, are valued at 3.00, offering a 33.3% chance of success. The odds indicate a tight game, with the hosts holding a narrow advantage.
Most recent head-to-head: Record favours Fiorentina
The previous meetings between these two clubs are limited, with their history showing only a single encounter. Their previous match was a club friendly played in 2018, which ended in a 0-0 draw.
Due to the lack of history, we must focus on the current six-game form across all competitions, with Die Nullfunfer having won one, drawn one and lost three of their last five matches, while La Viola have won one and lost two of their last six matches.
After reviewing our key Mainz 05 vs Fiorentina predictions, be sure to visit our website for the remaining football betting tips today.
Mainz 05 preview: No new injury concern
Bo Henriksen’s team heads into this clash without any recent injury aside from the players out on long-term injury. Maxim Dal remains sidelined with a cruciate ligament injury and is expected to return next year, while Anthony Caci is also out until the same period as he continues recovery from a tendon injury.
Predicted lineup: Zentner (GK), Hanche-Olsen, Maloney, Kohr, Mwene, Sano, Amiri, Widmer, Nebel, Hollerbach & Lee
Last five fixtures
- 01.11.25 – Mainz 1 – 1 Werder Bremen
- 29.10.25 – Mainz 0 – 2 Stuttgart
- 26.10.25 – Stuttgart 2 – 1 Mainz
- 23.10.25 – Mainz 1 – 0 Zrinjski
- 18.10.25 – Mainz 3 – 4 Bayer Leverkusen
Fiorentina preview: No new injuries in the team
Stefano Pioli’s team will have to face Mainz without Tariq Lamptey, who remains sidelined with a knee injury and is expected to return in November, while Christian Kouame is doubtful as he continues his recovery from a cruciate ligament injury and also, Robin Gosens is a doubt after sustaining an injury.
Predicted lineup: De Gea (GK), Pongracic, Comuzzo, Ranieri, Dodo, Ndour, Caviglia, Fagioli, Fortini, Dzeko & Kean
Last five fixtures
- 02.11.25 – Fiorentina 0 – 1 Lecce
- 29.10.25 – Inter 3 – 0 Fiorentina
- 26.10.25 – Fiorentina 2 – 2 Bologna
- 23.10.25 – SK Rapid 0 – 3 Fiorentina
- 19.10.25 – AC Milan 2 – 1 Fiorentina
Player to watch: Nelson Weiper

Nelson Weiper will play a big role in Mainz 05's game against Fiorentina. The forward has been impressive in his three games in the Europa League, scoring two goals in his first three games in the competition. He will be looking to help his team extend their win on Thursday.