Man Utd welcome Lyon to Old Trafford to contest season-defining Europa League quarter-final second-leg clash on Thursday, 17 April. Read our Europa League predictions for the contest below.
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Man Utd vs Lyon prediction: BTTS market appeals again
Key Stats
- Six of Man Utd's last seven Europa League fixtures have produced goals at both ends.
- 12 of Lyon’s last 13 games in all competitions have featured over 2.5 goals.
- Man Utd picked up four yellow cards in last week’s first leg against Lyon in France.
- In-form Lyon have lost only one of their last nine matches in all competitions.
Correct score prediction: Man Utd 1-1 Lyon
Man Utd and Lyon were well-matched in last week’s first leg in France and Thursday’s crucial return fixture could be just as keenly contested. BTTS has landed in six of United’s last seven Europa League matches, so expect similar here.
Pre-game odds and win probability: Lyon priced as underdogs
- HOME: 7/10 (1.70) – 58.8%
- DRAW: 31/10 (4.10) – 24.4%
- AWAY: 7/2 (4.50) – 22.2%
*odds from Ladbrokes, subject to change
A weakened Man Utd XI were hammered 4-1 by Newcastle on Sunday, however, despite that confidence-denting defeat, the Red Devils remain 7/10 favourites to secure victory against Lyon.
In-form Lyon eased to a fine 3-1 win at Auxerre in Ligue 1 at the weekend and they offer plenty of value at 7/2 to upset the odds at Old Trafford. View our free football tips page for more Europa League predictions.
Most recent H2Hs: Fixture has goal-scoring potential
Last week’s first leg featured four goals and 29 attempts combined from the teams and more excitement is anticipated on Thursday evening.
UEFA Europa League 10/04/25
Lyon
Man Utd
Elite Club Friendlies 19/07/23
Man Utd
Lyon
Man Utd preview: Zirkzee a big miss
Man Utd lost Joshua Zirkzee to a hamstring injury on Sunday, impacting their already limited attacking options. Rasmus Hojlund, Patrick Dorgu, Casemiro and Harry Maguire are all expected to return to the starting XI having been benched against Newcastle. Andre Onana should also return between the sticks.
Predicted lineup: Onana (GK), Mazraoui, Maguire, Yoro, Dalot, Ugarte, Casemiro, Dorgu, Garnacho, Fernandes, Hojlund
England Premier League 20/04/25
L
Wolverhampton
1
Man Utd
0
UEFA Europa League 17/04/25
W
Lyon
4
Man Utd
5
England Premier League 13/04/25
L
Newcastle
4
Man Utd
1
UEFA Europa League 10/04/25
D
Lyon
2
Man Utd
2
England Premier League 06/04/25
D
Man City
0
Man Utd
0
Lyon preview: Trio to return
Lyon rested Ashley Maitland-Niles, Jordan Veretout and Nicolas Tagliafico against Auxerre and all three should come back into the team on Thursday. Potent travellers Lyon have won five of their last six away games in all competitions.
Predicted lineup: Perri (GK), Maitland-Niles, Mata, Niakhate, Tagliafico, Veretout, Tolisso, Akoukou, Almada, Cherki, Mikautadze
France Ligue 1 20/04/25
L
St Etienne
2
Lyon
1
UEFA Europa League 17/04/25
L
Man Utd
5
Lyon
4
France Ligue 1 13/04/25
W
Auxerre
1
Lyon
3
UEFA Europa League 10/04/25
D
Man Utd
2
Lyon
2
France Ligue 1 05/04/25
W
Lille
1
Lyon
2
Player to watch – Georges Mikautadze
Lyon’s Georges Mikautadze troubled Man Utd with his pace and close control in last week’s first leg and the fleet-footed attacker could be a nuisance again with extra space to run into at Old Trafford.
Mikautadze’s running could trouble United
Mikautadze attempted five take-ons and carried the ball for 224 yards in last week’s first leg, and it’s clear that the 24-year-old backs himself to beat his markers. The Georgian international could be a real threat on the counter for Lyon at Old Trafford.