Bayer Leverkusen will welcome the in-form Eintracht Frankfurt to the BayArena on September 12 in the third game of the German Bundesliga.
The Factory XI have had a difficult start to the season and will be looking to get back to winning ways after a thrilling 3-3 draw against the Eagles in their last outing, while Frankfurt will be full of confidence after their impressive 3-1 victory over Hoffenheim.
Read our Leverkusen vs Frankfurt predictions and preview to find out, but remember to also check our other Bundesliga predictions.
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Leverkusen vs Frankfurt prediction: The Factory XI to win by a narrow margin
Key statistics
- The Factory XI have defeated Frankfurt in each of their last five encounters.
- Their last meeting ended in a 2-1 correct score.
- Over 2.5 goals have been scored in four of their last five clashes.
Correct score prediction: Leverkusen 2-1 Frankfurt
The Factory XI will be looking to continue their unbeaten run against the Eagles and we are predicting a 2-1 victory for Leverkusen. The home side have an excellent record against Frankfurt, especially on their own ground. On the other hand, Frankfurt have shown good form in recent weeks, and will make it difficult for Leverkusen to run them over as they have always done in previous meetings.
The history between these two clubs also suggests an open game, with plenty of scoring chances on both ends. While Frankfurt are capable of finding the net, Leverkusen’s firepower and home advantage should prove decisive.
Pre-match odds and win probability: No favourite odds from the Bookmakers
- Home: 13/10 (2.30) – 43.48%
- Draw: 27/10 (3.70) – 27.03%
- Away: 9/5 (2.80) – 35.71%
*Odds provided by Ladbrokes. Subject to change.*
Leverkusen at 2.30 means the bookmaker believes they have about a 43% chance of winning. A draw at 3.70 suggests around a 27% chance, while Frankfurt at 2.80 suggests roughly a 36% chance.
Most recent head-to-head: Leverkusen dominate encounters
The head-to-head history between Leverkusen and Frankfurt shows that the Factory XI have had the upper hand in recent years. Out of their last five meetings, Leverkusen have come out on top in all five games.
The most recent clash saw Leverkusen claim a solid 4-1 away win. Frankfurt have also not had a good outing at Leverkusen, but their newfound form should help them in the game. These results show that while Leverkusen have often dominated, Frankfurt should never be counted out.
Germany Bundesliga I 01/03/25
Eintracht Frankfurt
Bayer Leverkusen
Germany Bundesliga I 19/10/24
Bayer Leverkusen
Eintracht Frankfurt
Germany Bundesliga I 05/05/24
Eintracht Frankfurt
Bayer Leverkusen
Germany Bundesliga I 17/12/23
Bayer Leverkusen
Eintracht Frankfurt
Germany Bundesliga I 08/04/23
Bayer Leverkusen
Eintracht Frankfurt
After reviewing our key Leverkusen vs Frankfurt predictions, be sure to visit our website for the remaining football betting tips today.
Leverkusen preview: Injury crisis
Injuries are likely to play a role in shaping the team selections for this match. Jeanuel Belocian is currently sidelined with a knee injury, which keeps the German defender out of action and reduces depth at the back.
Jonas Hofmann is also unavailable as he struggles with a hamstring problem, limiting the French midfielder’s influence in attack and cr eativity. Meanwhile, Martin Terrier faces a longer recovery after suffering an Achilles tendon injury, a serious setback that rules the French forward out for the foreseeable future.
Predicted lineup: Flekken (GK), Grimaldo, Quansah, Tapsoba, Aleix, Tillman, Andrich, Tape, Schick, Tella & Kofane
Last five fixtures
- 30.08.25 – Werder Bremen 3 – 3 Bayer Leverkusen
- 23.08.25 – Bayer Leverkusen 1 – 2 Hoffenheim
- 15.08.25 – Grossaspach 0 – 4 Bayer Leverkusen
- 08.08.25 – Chelsea 2 – 0 Bayer Leverkusen
- 05.08.25 – Bayer Leverkusen 3 – 0 Pisa
Frankfurt preview: Looking to continue good run
There are injury concerns ahead of the upcoming match, with a couple of key players forced to miss out. Kaua Santos is sidelined in Germany with a knee injury, a setback that affects defensive stability and limits squad depth.
Jessic Ngankam is also unavailable due to a leg injury, which reduces attacking options and puts extra pressure on the forwards who are fit to play.
Predicted lineup: Zetterer (GK), Collins, Theate, Koch, Kristensen, Larsson, Uzun, Wahi, Doan, Chaibi & Bahoya
Last five fixtures
- 30.08.25 – Hoffenheim 1 – 3 Eintracht Frankfurt
- 23.08.25 – Eintracht Frankfurt 4 – 1 Werder Bremen
- 17.08.25 – Engers 0 – 5 Eintracht Frankfurt
- 09.08.25 – Fulham 1 – 0 Eintracht Frankfurt
- 02.08.25 – Philadelphia Union 2 – 2 Eintracht Frankfurt
Player to watch: Patrik Schick
Every big game has players who can make the difference and for Leverkusen, the one to watch is their star striker, Patrik Schick. He has started the season strongly, scoring two goals in his previous Bundesliga game.

Schick’s strength lies in his excellent finishing and his instinct to be in the right place at the right time, making him a constant danger inside the penalty area. His form and confidence mean he could play a decisive role in this match and the Frankfurt defence will need to be at their best to keep him quiet.