Bayer Leverkusen vs Cologne prediction, odds & betting tips – 05/02/2025

Bayer Leverkusen welcome second-tier Cologne to the BayArena to contest a German DFB Pokal quarter-final clash on Wednesday, 5 February. Read our German football predictions for the fixture below.

Bayer Leverkusen vs Cologne prediction: Hosts should be comfortable

Key Stats

• Bayer Leverkusen have won nine home games in a row in all competitions.
• Leverkusen notched three times in two of their last three home assignments.
• Cologne failed to score in each of their last two tussles with Bayer Leverkusen.
• Patrik Schick has hit nine goals in his last eight appearances for Die Werkself.

Correct score prediction: Bayer Leverkusen 3-0 Cologne

Bayer Leverkusen rattled the net three times in two of their last three home matches and Die Werkself are targeting a 10^th win on the spin at the BayArena. Back Leverkusen to triumph with ease here.

Pre-game odds and win probability: Bayer Leverkusen are odds-on favourites

• HOME: 1/4 (1.25) – 80%
• DRAW: 5/1 (6.00) – 16.7%
• AWAY: 9/1 (10.00) – 10%

*odds from Ladbrokes, subject to change

Bayer Leverkusen eased to a 3-1 win over Hoffenheim in the Bundesliga at the weekend and Die Werkself should find sailing just as smooth when they host Cologne in the cup in midweek.

Cologne are top of the pile in the 2. Bundesliga and have their eyes on promotion this term, however, they have just a 10% chance of upsetting the odds at Bayer Leverkusen on Wednesday. Read more of our latest football predictions and German football analysis on our dedicated page.

Most recent H2Hs: Leverkusen have been on top

Bayer Leverkusen have won three of their last four meetings with Cologne. Over 2.5 goals has landed in three of the teams’ last four tussles.

Germany Bundesliga I 03/03/24

Cologne

0

Bayer Leverkusen

2

Germany Bundesliga I 08/10/23

Bayer Leverkusen

3

Cologne

0

Germany Bundesliga I 05/05/23

Bayer Leverkusen

1

Cologne

2

Germany Bundesliga I 09/11/22

Cologne

1

Bayer Leverkusen

2

Germany Bundesliga I 13/03/22

Bayer Leverkusen

0

Cologne

1

Bayer Leverkusen preview: Grimaldo suspended

Martin Terrier and Jeanuel Belocian are out injured though Robert Andrich is back from suspension. Alex Grimaldo was sent off at the weekend and will sit Wednesday's game out. Head Coach Xabi Alonso could make changes to his starting XI in midweek.

Predicted lineup: Kovar (GK), Mukiele, Tah, Hincapie, Frimpong, Palacios, Garcia, Hermoso, Buendia, Tella, Schick

Germany Bundesliga I 11/05/25

L

Borussia Dortmund

4

Bayer Leverkusen

2

Germany Bundesliga I 04/05/25

D

SC Freiburg

2

Bayer Leverkusen

2

Germany Bundesliga I 26/04/25

W

Augsburg

0

Bayer Leverkusen

2

Germany Bundesliga I 20/04/25

D

St Pauli

1

Bayer Leverkusen

1

Germany Bundesliga I 12/04/25

D

Union Berlin

0

Bayer Leverkusen

0

Cologne preview: Visitors face tough test

Cologne came from behind to pick up three points at Eintracht Braunschweig at the weekend. Cologne knocked Holstein Kiel and Hertha Berlin out in the previous two rounds of the DFB Pokal, though a test against Bayer Leverkusen is far stiffer.

Predicted lineup: Schwabe (GK), Hubers, Schmied, Heintz, Gazibegovic, Ljubicic, Martel, Paqarada, Kainz, Downs, Tigges

Germany Bundesliga II 09/05/25

W

Nurnberg

1

Cologne

2

Germany Bundesliga II 03/05/25

D

Jahn Regensburg

1

Cologne

1

Germany Bundesliga II 27/04/25

L

Hannover 96

1

Cologne

0

Germany Bundesliga II 20/04/25

W

SC Preussen Munster

1

Cologne

3

Germany Bundesliga II 11/04/25

D

Greuther Furth

1

Cologne

1

Player to watch – Emiliano Buendia

Argentinean midfielder Emiliano Buendia has joined Bayer Leverkusen from English Premier League side Aston Villa on loan for the rest of the campaign and the schemer could be handed a start in midweek.

Buendia will be eager to shine

Buendia is a clever, creative attacking midfielder and the 28-year-old has the quality to make a telling impact if chosen to start against Cologne in the DFB Pokal on Wednesday evening.