An interesting fixture is on the cards as Lecce host Serie A leaders Napoli at Via del Mare on Tuesday, 28 October 2025.
View our free Lecce vs Napoli predictions below.
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Lecce vs Napoli predictions: Visitors to lead at the break
Key stats
- Lecce conceded first in five of their last six encounters with Napoli.
- Napoli led at half-time in their last five trips to this stadium.
- The last three skirmishes between these sides went below the 1.5-goal threshold.
Correct score prediction: Lecce 0-2 Napoli
As things stand, Lecce are still hunting for their first home win of the season. Eusebio Di Francesco's men are up against a Napoli side that won six of eight Serie A games this campaign.
Moreover, Napoli have an excellent track record against Lecce, winning four of the last five meetings between these teams while keeping four clean sheets.
Taking everything into account, we are confident that the Partenopei will win without conceding.
Pre-game odds and win probability: Napoli are overwhelming favourites
- HOME: 11/2 (6.50) – 15.4%
- DRAW: 16/5 (4.20) – 23.8%
- AWAY: 1/2 (1.50) – 66.7%
*Odds from Ladbrokes, subject to change
After suffering back-to-back defeats against Torino and PSV Eindhoven, Napoli returned to winning ways last weekend with an impressive 3-1 victory over Inter Milan.
With 18 points from a possible 24, Antonio Conte’s troops are leading the Serie A standings ahead of their clash with 16th-placed Lecce, who have a 1-3-4 win-draw-loss record.
Considering Lecce's struggles this campaign, it is no surprise that Napoli are the expected winners at 1/2 (1.50). Teams with these odds generally have a 66.7% probability of winning.
Don’t forget to check out more of our best betting tips and predictions after you’ve dissected our Lecce vs Napoli predictions.
Also, keeping in mind that Napoli had the lead at the half-time break in their last five trips to this stadium, HT Napoli to win has an appealing look at 21/20 (2.05). That one has a 48.8% chance of landing.
Most recent H2Hs: Business as usual for Napoli?
Napoli are unbeaten in their last six meetings with Lecce (W4, D2) and did not concede a single goal in their last four encounters.
Italy Serie A 03/05/25
Lecce
Napoli
Italy Serie A 26/10/24
Napoli
Lecce
Italy Serie A 26/05/24
Napoli
Lecce
Italy Serie A 30/09/23
Lecce
Napoli
Italy Serie A 07/04/23
Lecce
Napoli
Lecce preview: Still hunting for their first home win
Lecce finished Saturday’s contest at Bluenergy Stadium with no new injury concern. This means that coach Di Francesco will remain without the usual absentees, who include Matias Per Sepulveda (thigh), Gaby Jean (ACL), Riccardo Sottil, and Filip Marchwinski.
Predicted lineup: Falcone (GK), Gallo, Gabriel, Gaspar, Veiga, Berisha, Ramadani, Morente, Helgason, Pierotti & N’Dri.
Last five matches
- Udinese 3-2 Lecce
- Lecce 0-0 Sassuolo
- Parma 0-1 Lecce
- Lecce 2-2 Bologna
- Milan 3-0 Lecce
Napoli preview: No De Bruyne, no problem?
In the recent 3-1 victory over Inter Milan, Napoli were without Stanislav Lobotka, Amir Rrahmani, Rasmus Hojlund, Alex Meret, and talisman Romelu Lukaku due to injury.
However, the situation has worsened for the Partenopei as midfield maestro Kevin De Bruyne and forward David Neres became the latest casualties in that game, which means Conte is left with fewer options for the clash against Lecce.
Predicted lineup: Milinkovic-Savic (GK), Di Lorenzo, Jesus, Buongiorno, Spinazzola, Gilmour, Politano, Anguissa, Olivera, McTominay & Lang.
Last five matches
- Napoli 3-1 Inter Milan
- PSV 6-2 Napol
- Torino 1-0 Napoli
- Napoli 2-1 Genoa
- Napoli 2-1 Sporting
Player to watch: Frank Anguissa
In the absence of De Bruyne, Napoli will turn to Frank Anguissa to provide the goals. The former Fulham midfielder was on the scoresheet last weekend and has four goal contributions in his last seven Serie A assignments.