Lazio vs Roma prediction, odds & betting tips 21/09/2025
Can Roma claim a victory here? - Photo by Imago
🔥 Our Hot tip

Under 3.5 Goals

Four of the last fixtures of both teams produced fewer than three total goals.

Lazio and Rome will resume their rivalry and go head-to-head in the Rome Derby at the Stadio Olimpico on Sunday. The home side have won only one of their three Serie A fixtures, while the away side have fared better with two victories in three league fixtures.

That said, this is a derby, and both sides will fight for the bragging rights this weekend. However, the away side have a lot to prove this weekend.

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Lazio vs Roma prediction: This fixture can go either way.

Key statistics

  • Lazio have won three of their last five matches.
  • Roma have also claimed three victories in their last five fixtures.
  • Four of the last fixtures of both teams produced fewer than three total goals.

Correct score prediction: Lazio 1-1 Roma

Lazio and Roma are eternal rivals, and that rivalry will be renewed when they clash at the Stadio Olimpico on Sunday. The away side have had a better start to the season with two wins in three league fixtures.

Although that is not the case with the hosts, who have managed only a victory in their opening three league fixtures. However, with the nature of this fixture, the outcome is likely to be a 1-1 draw, considering the results both teams have posted so far.

Pre-match odds and win probability: The hosts are underdogs in this encounter

  • Home: 7/4 (2.75) – 36.40%
  • Draw: 21/10 (3.10) – 32.30%
  • Away: 8/5 (2.60) – 38.50%

*Odds provided by Ladbrokes. Subject to change.*

AS Roma will go into this encounter as the favourites, considering they have recorded better results since the start of the season. More so, the bookies have priced them at 8/5 (2.60), which represents a 38.50% chance for the visiting side to claim a win.

That said, the home side also have decent odds, plus they can not be written off in this fixture, given the nature of the encounter. According to bookmakers, 7/4 (2.75), which translates to a 38.50% chance of the hosts winning on Sunday.

Most recent head-to-head: Lazio are looking for their first win in three fixtures

Lazio lost a game and drew another one against Roma in April 2025, meaning they are winless in their last three meetings against Sunday's opponents. When they file out on Sunday, they will be looking to best their city rivals this weekend.

Italy Serie A 13/04/25

Lazio

Lazio

1
Roma

Roma

1

Italy Serie A 05/01/25

Roma

Roma

2
Lazio

Lazio

0

Italy Serie A 06/04/24

Roma

Roma

1
Lazio

Lazio

0

Coppa Italia 10/01/24

Lazio

Lazio

1
Roma

Roma

0

Italy Serie A 12/11/23

Lazio

Lazio

0
Roma

Roma

0

Aside from this tip,we have more  football betting tips today.

Lazio Preview: The hosts will miss a few players

Gigot Samuel is still recuperating from a back injury, and he will not be in action on Sunday, when these two sides clash.

Manuel Lazzari is struggling with a calf injury, and he is not expected to be involved on Sunday at the  Stadio Olimpico. Another player not expected is Matias Vecino, who is sidelined with a muscle injury.

Predicted lineup: Provedel (GK), Tavares, Prostvgaard, Gila, Marusic, Dele-Bashiru, Guendouzi, Zaccagni, Castellanos, Cataldi & Cancellieri.

Last five fixtures

  • 14.09.25 – Sassuolo 1 – 0 Lazio
  • 30.08.25 – Lazio 4 – 0 Verona
  • 24.08.25 – Como 2 – 0 Lazio
  • 16.08.25 – Lazio 2 – 0 Atromitos
  • 09.08.25 – Burnley 0 – 1 Lazio

Roma preview: Paulo Dybala will sit out this contest

Roma are not without problems of their own, with Leon Bailey sidelined with a thigh injury, while Paulo Dybala is a doubt for this fixture as a result of a muscle injury.

Edoardo Bove is a long-term absentee due to heart issues, and he is not expected to be involved any time soon.

Predicted lineup: Svilar (GK), Mancini, Hermoso, Wesley, Cristante, Koney, Angelino, El Shaarawy, Soule & Fergusson

Last five fixtures

  • 14.09.25 – Roma 1 – 0 Torino
  • 30.08.25 – Pisa o – 1 Roma
  • 24.08.25 – Roma 1 – 0 Bologna
  • 16.08.25 – Roma 2 – 2 Neom
  • 09.08.25 – Everton 0 – 1 Roma

Player to watch: Matias Soule

Although Matias Soule has found the back of the net only once this term, he is still a key player for AS Roma. His trickery is a major asset, and he will surely cause some problems for the Lazio defence on Sunday.

Matias Soule – Photo by Imago

 

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Ademola is a passionate sports writer and betting expert with a degree in Plant Science and a Masters degree in Plant Ecology.